1799506-06-1
Chemical Structure
VH032-PEG5-C6-Cl
Synonym(s): HaloPROTAC 2
- No. CAS: 1799506-06-1
- Formula:C38H59ClN4O9S
- Molecular Weight:783.41
IUPAC Name: (2S,4R)-1-((S)-2-(tert-butyl)-24-chloro-4-oxo-6,9,12,15,18-pentaoxa-3-azatetracosanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
InChIKey: ADYHVGXLTSRLTE-MEEYNGGZSA-N
SMILES: O=C(NCC1=CC=C(C2=C(C)N=CS2)C=C1)[C@H]3N(C([C@H](C(C)(C)C)NC(COCCOCCOCCOCCOCCCCCCCl)=O)=O)C[C@H](O)C3
Biological Activity: VH032-PEG5-C6-Cl (HaloPROTAC 2) is a conjugate of ligands for E3 and 21-atom-length linker. The connector of linker is Halogen group. VH032-PEG5-C6-Cl incorporates the VH032 based VHL ligand and 5-unit PEG linker. VH032-PEG5-C6-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays[1].
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VH032-PEG5-C6-Cl | 99.93% | VH032-PEG5-C6-Cl (HaloPROTAC 2) is a conjugate of ligands for E3 and 21-atom-length linker. The connector of linker is Halogen group. VH032-PEG5-C6-Cl incorporates the VH032 based VHL ligand and 5-unit PEG linker. VH032-PEG5-C6-Cl is capable of inducing the degradation of GFP-HaloTag7 in cell-based assays. | ||||||||||||||||||||
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Keywords
