10 Results for "

PGJ2

" in MedChemExpress (MCE) Product Catalog:
Products (10)

10 Results for "PGJ2" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-108568
CAS No.: 87893-55-8
Purity:  97.50%
Synonyms: 15d-PGJ2; 15-Deoxy-Δ12,14-PGJ2
15-Deoxy-Δ-12,14-prostaglandin J2 (15d-PGJ2) is a cyclopentenone prostaglandin and a metabolite of PGD2. 15-Deoxy-Δ-12,14-prostaglandin J2 is a selective PPARγ (EC50 of 2 µM) and a covalent PPARδ agonist. 15-Deoxy-Δ-12,14-prostaglandin J2 promotes efficient differentiation of C3H10T1/2 fibroblasts to adipocytes with an EC50 of 7 μM [2].
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1
1 Cited Publications
Cat. No.: HY-108568S
CAS No.: 1542166-82-4
Purity:  98.10%
Synonyms: 15d-PGJ2-d4; 15-Deoxy-Δ12,14-PGJ2-d4
15-Deoxy-Δ-12,14-prostaglandin J2-d4 is the deuterium labeled 15-Deoxy-Δ-12,14-prostaglandin J2. 15-Deoxy-Δ-12,14-prostaglandin J2 (15d-PGJ2) is a cyclopentenone prostaglandin and a metabolite of PGD2. 15-Deoxy-Δ-12,14-prostaglandin J2 is a selective PPARγ (EC50 of 2 μM) and a covalent PPARδ agonist. 15-Deoxy-Δ-12,14-prostaglandin J2 promotes efficient differentiation of C3H10T1/2 fibroblasts to adipocytes with an EC50 of 7 μM [2].
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Cat. No.: HY-113366
CAS No.: 60203-57-8
Purity:  98.10%
Synonyms: PGJ2
Prostaglandin J2 (PGJ2), an endogenous metabolite of Prostaglandin D2 (PGD2; HY-101988), is a potent PGD2 receptor (DP) agonist with Kis of 0.9 nM and 6.6 nM for hDP and hCRTH2, respectively. Prostaglandin J2 stimulates intracellular cyclic AMP production with an EC50 value of 1.2 nM. Prostaglandin J2 induces oxidative stress and neuronal apoptosis. Prostaglandin J2 induces the accumulation/aggregation of ubiquitinated (Ub) proteins. Prostaglandin J2 is highly neurotoxic and potentially contributes to many neurodegenerative conditions, including Alzheimer's (AD) and Parkinson's diseases (PD) [2] .
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Cat. No.: HY-113505
CAS No.: 87893-54-7
Purity:  ≥99.0%
Synonyms: Δ12-PGJ2
Delta-12-Prostaglandin J2 (Δ12-PGJ2) is a cyclopentenone prostaglandin (PG) with anti-proliferative effect on various tumor cell growth. Delta-12-Prostaglandin J2, a naturally occurring dehydration product of prostaglandin D2, is able to induce apoptosis in HeLa cells via caspase activation [2].
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Cat. No.: HY-125737
Synonyms: 15-Deoxy-Δ12,14-PGJ2 Glutathione
Research Areas:  

Others

15-deoxy-Δ12,14-Prostaglandin J2 glutathione (15-deoxy-Δ12,14-PGJ2 glutathione) is a non-enzymatic adduct formed from 15-deoxy-Δ12,14-PGJ2 and glutathione. The biological properties of this compound have not been characterized.
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Cat. No.: HY-117422
CAS No.: 596104-94-8
Synonyms: 11-Oxo-prosta-5Z,12E,14Z-trien-1-oic acid
Target:  

PPAR

Research Areas:  

Cancer

CAY10410 (11-Oxo-prosta-5Z), a 15d-PGJ2 analog, is a potent PPARγ agonist. CAY10410 has the ability to activate PPARγ in human B cells without killing B lymphocytes .
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Cat. No.: HY-172633
Synonyms: 15-Deoxy-Δ12,14-PGJ2 serinol amide
Target:  

Drug Derivative

Research Areas:  

Others

15-Deoxy-Δ12,14-prostaglandin J2 serinol amide (15-Deoxy-Δ12,14-PGJ2 serinol amide) is a derivative of 15-deoxy-Δ12,14-PGJ2-2-glyceryl ester .
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Cat. No.: HY-N15483
CAS No.: 2230717-14-1
Synonyms: 13,14-Dihydro-15-keto-PGJ2
13,14-Dihydro-15-keto prostaglandin J2 (13,14-Dihydro-15-keto-PGJ2) is the dehydration product of 13,14-dihydro-15-keto PGD2 (HY-118830) .
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Cat. No.: HY-176243
CAS No.: 1947405-90-4
15-Deoxy-Δ12,14-Prostaglandin J2-2-glyceryl ester is a derivate of 15-Deoxy-Δ-12,14-prostaglandin J2 (HY-108568). 15-Deoxy-Δ-12,14-prostaglandin J2 (15d-PGJ2) is a cyclopentenone prostaglandin and a metabolite of PGD2. 15-Deoxy-Δ-12,14-prostaglandin J2 is a selective PPARγ (EC50 of 2 µM) and a covalent PPARδ agonist. 15-Deoxy-Δ-12,14-prostaglandin J2 promotes efficient differentiation of C3H10T1/2 fibroblasts to adipocytes with an EC50 of 7 μM [2] .
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Cat. No.: HY-D3313
Synonyms: 15-Deoxy-Δ12,14-PGJ2-biotin
15-Deoxy-Δ12,14-Prostaglandin J2-biotin is a biotin-labled 15-Deoxy-Δ12,14-Prostaglandin J2 (HY-108568). 15-Deoxy-Δ12,14-Prostaglandin J2-biotin is a biotin can be used as a fluorescent probe.
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