2. Metabolic Enzyme/Protease Apoptosis
  3. Endogenous Metabolite Apoptosis
  4. Delta-12-Prostaglandin J2

Delta-12-Prostaglandin J2  (Synonyms: Δ12-PGJ2)

Cat. No.: HY-113505
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Delta-12-Prostaglandin J2 (Δ12-PGJ2) is a cyclopentenone prostaglandin (PG) with anti-proliferative effect on various tumor cell growth. Delta-12-Prostaglandin J2, a naturally occurring dehydration product of prostaglandin D2, is able to induce apoptosis in HeLa cells via caspase activation.

For research use only. We do not sell to patients.

Delta-12-Prostaglandin J2 Chemical Structure

Delta-12-Prostaglandin J2 Chemical Structure

CAS No. : 87893-54-7

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Based on 1 publication(s) in Google Scholar

Delta-12-Prostaglandin J2 Related Antibodies

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Description

Delta-12-Prostaglandin J2 (Δ12-PGJ2) is a cyclopentenone prostaglandin (PG) with anti-proliferative effect on various tumor cell growth. Delta-12-Prostaglandin J2, a naturally occurring dehydration product of prostaglandin D2, is able to induce apoptosis in HeLa cells via caspase activation[1][2].

IC50 & Target

Human Endogenous Metabolite

 

Molecular Weight

334.45

Formula

C20H30O4
CAS No.
SMILES

CCCCC[C@H](O)C/C=C1[C@H](C=CC\1=O)C/C=C\CCCC(O)=O
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Delta-12-Prostaglandin J2 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Delta-12-Prostaglandin J287893-54-7Δ12-PGJ2Endogenous MetaboliteApoptosisgrowthcyclopentenone prostaglandinprostaglandin D2caspaseanti-neoplasticHeLa cellsInhibitorinhibitorinhibit

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