PPARgamma

By Targets:	Cytochrome P450 (2) Leukotriene Receptor (2) PPAR (7) Reference Standards (1) Small Interfering RNA (siRNA) (2)
By Research Areas:	Metabolic Disease (5)
Oligonucleotides:	Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (2)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-101676

RG-12525 NID 525	Leukotriene Receptor PPAR Cytochrome P450	Metabolic Disease
RG-12525 is a a specific, competitive and orally effective antagonist of the peptidoleukotrienes, LTC4, LTD4 and LTE4, inhibiting LTC4-, LTD4- and LTE4-inducd guinea pig parenchymal strips contractions, with IC₅₀s of 2.6 nM, 2.5 nM and 7 nM, respectively; RG-12525 is also a peroxisome proliferator-activated receptor gamma (PPAR-gamma) agonist with IC₅₀ of appr 60 nM and a potent inhibitor of CYP3A4, with a K_i value of 0.5 µM.

HY-139114

20-Carboxyarachidonic acid	PPAR	Metabolic Disease
20-Carboxyarachidonic acid, a relatively stable metabolite of 20-HETE, is an endogenous dual activator of PPARalpha and *PPARgamma* .

HY-RS10926

Pparg Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA) PPAR	Others
Pparg Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pparg gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Pparg Mouse Pre-designed siRNA Set A Pparg Mouse Pre-designed siRNA Set A

HY-RS10925

PPARG Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA) PPAR	Others
PPARG Human Pre-designed siRNA Set A contains three designed siRNAs for PPARG gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

PPARG Human Pre-designed siRNA Set A PPARG Human Pre-designed siRNA Set A

HY-U00259

BM152054	PPAR	Metabolic Disease
BM152054 is a potent *PPARgamma*-activator. BM152054 can promote glucose utilization in peripheral tissues by enhancing insulin action .

HY-117459

E-3030 free acid	PPAR	Metabolic Disease
E-3030 free acid is a potent dual activator of peroxisome proliferator-activated receptor (PPAR) alpha and PPARgamma, exhibiting significant antidiabetic and lipid-modulating effects. E-3030 decreases blood glucose, triglyceride, non-esterified fatty acids, and insulin levels, while increasing blood adiponectin levels. E-3030 improves glucose tolerance and shows remarkable triglyceride- and non-high-density lipoprotein cholesterol-lowering effects in animal models.

HY-101676R

RG-12525 (Standard) NID 525 (Standard)	Leukotriene Receptor Reference Standards PPAR Cytochrome P450	Metabolic Disease
RG-12525 (Standard) is the analytical standard of RG-12525 (HY-101676). This product is intended for research and analytical applications. RG-12525 is a a specific, competitive and orally effective antagonist of the peptidoleukotrienes, LTC4, LTD4 and LTE4, inhibiting LTC4-, LTD4- and LTE4-inducd guinea pig parenchymal strips contractions, with IC50s of 2.6 nM, 2.5 nM and 7 nM, respectively; RG-12525 is also a peroxisome proliferator-activated receptor gamma (PPAR-gamma) agonist with IC50 of appr 60 nM and a potent inhibitor of CYP3A4, with a Ki value of 0.5 μM.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-139114

20-Carboxyarachidonic acid	Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	PPAR
20-Carboxyarachidonic acid, a relatively stable metabolite of 20-HETE, is an endogenous dual activator of PPARalpha and *PPARgamma* .

Recombinant Proteins Recommended:

PPAR gamma

Species:	Human (4) Mouse (1)
Tag:	His (4) Tag Free (1) GST (1)
Source:	P. pastoris (1) Sf9 insect cells (1) E. coli (3)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P701336

	PPAR gamma Protein, Human PPARG; Peroxisome proliferator-activated receptor gamma; PPAR-gamma; Nuclear receptor subfamily 1 group C member 3	Human	E. coli
	The PPAR gamma protein is a nuclear receptor that binds to peroxisome proliferators and is activated upon ligand binding to specific PPREs on DNA. It regulates target gene transcription and controls fatty acid metabolism. PPAR gamma Protein, Human is the recombinant human-derived PPAR gamma protein, expressed by E. coli , with tag free.

HY-P705437

	PPAR gamma Protein, Mouse (His) Pparg; Nr1c3; Peroxisome proliferator-activated receptor gamma; PPAR-gamma; Nuclear receptor subfamily 1 group C member 3	Mouse	E. coli
	PPAR gamma is a regulator of adipocyte differentiation and glucose homeostasis, belonging to nuclear receptor protein families. PPAR gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. PPAR gamma Protein, Mouse (His) is expressed by E. coli and carries a N-terminal 10*His tag.

HY-P73701

	PPAR gamma Protein, Human (sf9, His-GST) CIMT1; GLM1; NR1C31; PPARG2; PPARG5; PPARgamma; PPARG	Human	Sf9 insect cells
	The PPAR gamma protein is a nuclear receptor that binds to peroxisome proliferators and is activated upon ligand binding to specific PPREs on DNA. It regulates target gene transcription and controls fatty acid metabolism. PPAR gamma Protein, Human (sf9, His-GST) is the recombinant human-derived PPAR gamma protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.

HY-P790012Y

	PPAR-gamma Protein, Human (271a.a, His, solution) CIMT1; GLM1; NR1C31; PPARG2; PPARG5; PPARgamma; PPARG	Human	E. coli
	The PPAR gamma protein is a nuclear receptor that binds to peroxisome proliferators and is activated upon ligand binding to specific PPREs on DNA. It regulates target gene transcription and controls fatty acid metabolism. PPAR-gamma Protein, Human (271a.a, His, solution) is the recombinant human-derived PPAR-gamma protein, expressed by E. coli , with labeled tag.

HY-P702572

	PPAR gamma Protein, Human (P.pastoris, His) CIMT1, GLM1, NR1C31, PPARG2, PPARG5, PPARgamma, PPARG	Human	P. pastoris
	The PPAR gamma protein is a nuclear receptor that binds to peroxisome proliferators and is activated upon ligand binding to specific PPREs on DNA. It regulates target gene transcription and controls fatty acid metabolism. PPAR gamma Protein, Human (P.pastoris, His) is the recombinant human-derived PPAR gamma protein, expressed by P. pastoris , with N-6*His labeled tag.

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Host:	Mouse (2) Rabbit (5)
Reactivity:	Human (6) Bovine (1) Rat (7) Mouse (6) Rabbit (1) Sheep (1) Goat (1) Dog (1) Pig (1)
Application:	IHC-P (1) ICC/IF (1) IP (1) WB (7)
Isotype:	IgG (5)
Conjugation:	Non-conjugated (7)
Clonality:	Polyclonal (1) Monoclonal (5) Recombinant (3)
Modification:	Unmodified (6)

Cat. No.	Compare	Product Name	Application	Reactivity	Image

HY-P85702

	PPAR gamma Antibody (YA5394) Peroxisome proliferator-activated receptor gamma; PPAR-gamma; Nuclear receptor subfamily 1 group C member 3;	WB, IHC-P, IP	Human, Mouse, Rat
	PPAR gamma Antibody (YA5394) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to PPAR gamma.

HY-P85457

	PPAR gamma Antibody (YA5149) PPARG; NR1C3; Peroxisome proliferator-activated receptor gamma; PPAR-gamma; Nuclear receptor subfamily 1 group C member 3	WB, ICC/IF	Human, Mouse, Rat, Bovine, Dog, Goat, Pig, Rabbit, Sheep
	PPAR gamma Antibody (YA5149) is a Mouse-derived and non-conjugated monoclonal antibody, targeting to PPAR gamma.

HY-P80436

	PPAR gamma Antibody (YA122) 1 Publications Verification	WB	Human, Rat
	PPAR gamma Antibody (YA122) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PPAR gamma.

HY-P80783

	PGC1 alpha Antibody 1 Publications Verification PPARGC1A; LEM6; PGC1; PGC1A; PPARGC1; Peroxisome proliferator-activated receptor gamma coactivator 1-alpha; PGC-1-alpha; PPAR-gamma coactivator 1-alpha; PPARGC-1-alpha; Ligand effect modulator 6	WB	Human, Mouse, Rat
	PGC1 alpha Antibody is a Rabbit-derived and non-conjugated IgG polyclonal antibody, targeting to PGC1 alpha.

HY-P80783A

	PGC1 alpha Antibody (YA7180) 1 Publications Verification PPARGC1A; LEM6; PGC1; PGC1A; PPARGC1; Peroxisome proliferator-activated receptor gamma coactivator 1-alpha; PGC-1-alpha; PPAR-gamma coactivator 1-alpha; PPARGC-1-alpha; Ligand effect modulator 6	WB	Human, Mouse, Rat
	PGC1 alpha Antibody is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PGC1 alpha.

HY-P85326

	PGC1 alpha Antibody (YA5018) PPARGC1A; LEM6; PGC1; PGC1A; PPARGC1; Peroxisome proliferator-activated receptor gamma coactivator 1-alpha; PGC-1-alpha; PPAR-gamma coactivator 1-alpha; PPARGC-1-alpha; Ligand effect modulator 6	WB	Mouse, Rat
	PGC1 alpha Antibody (YA5018) is a Rabbit-derived and non-conjugated monoclonal antibody, targeting to PGC1 alpha.

HY-P80783AA

	PGC1 alpha Antibody (YA7180)(PBS only) PPARGC1A; LEM6; PGC1; PGC1A; PPARGC1; Peroxisome proliferator-activated receptor gamma coactivator 1-alpha; PGC-1-alpha; PPAR-gamma coactivator 1-alpha; PPARGC-1-alpha; Ligand effect modulator 6	WB	Human, Mouse, Rat
	PGC1 alpha Antibody is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PGC1 alpha.

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Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / In-stock - + Add to Cart Get quote

Cat. No.	Product Name		Classification

HY-RS10926

Pparg Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Pparg Mouse Pre-designed siRNA Set A contains three designed siRNAs for Pparg gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS10925

PPARG Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
PPARG Human Pre-designed siRNA Set A contains three designed siRNAs for PPARG gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
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