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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
17 Results for "
PSEN1
" in MedChemExpress (MCE) Product Catalog:
Products (17)
17 Results for "PSEN1" in MCE Product Catalog:
4
4 Cited Publications
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MRK-560, a chemical probe, is an orally active, brain barrier-penetrated γ-Secretase inhibitor, reducing Aβ peptide in rat brain and cerebrospinal fluid. MRK-560 decreases mutant NOTCH1 processing by selectively inhibiting PSEN1. MRK-560 can be used in studies of Alzheimer's disease and T-cell acute lymphoblastic leukaemia (T-ALL) [1] .
Cat. No.: HY-W015515
CAS No.: 7540-51-4
Synonyms: (S)-3,7-Dimethyloct-6-en-1-ol
Cat. No.: HY-W015515R
CAS No.: 7540-51-4
Synonyms: (S)-3,7-Dimethyloct-6-en-1-ol (Standard)
Cat. No.: HY-P1378A
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Cat. No.: HY-RS11276
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PSEN1 Human Pre-designed siRNA Set A contains three designed siRNAs for PSEN1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS18076
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Psen1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Psen1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS24551
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Psen1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Psen1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-156011
CAS No.: 3054220-62-8
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PSEN1-IN-1 (Compound (+)-13b) is a PSEN1 inhibitor. PSEN1-IN-1 inhibits PSEN1-APH1A and PSEN1-APH1B complex with IC50s of 19 and 5.5 nM. PSEN1-IN-1 can be used for Alzheimer's disease research [1].
Cat. No.: HY-156012
CAS No.: 3054220-07-1
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PSEN1-IN-2 (Compound 13K) is a PSEN1 inhibitor. PSEN1-IN-2 inhibits PSEN1-APH1A and PSEN1-APH1B complex with IC50s of 6.9 and 2.4 nM. PSEN1-IN-2 can be used for Alzheimer's disease research [1].
Cat. No.: HY-P1378
CAS No.: 134500-80-4
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Cat. No.: HY-178128
CAS No.: 1093975-58-6
PSEN1-IN-3 is a modulator of Gamma secretase complex.
Cat. No.: HY-P82123A
Synonyms: PSEN1; AD3; PS1; PSNL1; Presenilin-1; PS-1; Protein S182
Cat. No.: HY-180997
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Aβ aggregation-IN-5 is a brain-penetrant amyloid-β aggregation inhibitor. Aβ aggregation-IN-5 inhibits Aβ aggregation/oligomerization, rescues cells from AB/ROS toxicity and reduces microglial activation/NO production. Aβ aggregation-IN-5 reduces amyloid burden, neuroinflammation, microglial activation in APP/PSEN1 mice. Aβ aggregation-IN-5 can be used for the research of Alzheimer's disease [1].
Cat. No.: HY-P1383
CAS No.: 1315378-77-8
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
