7540-51-4
Chemical Structure
L-Citronellol
Synonym(s): (S)-3,7-Dimethyloct-6-en-1-ol
- CAS No.: 7540-51-4
- Formula:C10H20O
- Molecular Weight:156.27
IUPAC Name: (S)-3,7-dimethyloct-6-en-1-ol
InChIKey: QMVPMAAFGQKVCJ-JTQLQIEISA-N
SMILES: C/C(C)=C\CC[C@H](C)CCO
Biological Activity: L-Citronellol ((S)-3,7-Dimethyloct-6-en-1-ol) is a natural product with anti-allergic and neuroprotective effects. L-Citronellol inhibits mast cell activation and the release of inflammatory factors by inhibiting the ERK pathway. L-Citronellol inhibits BACE1/PSEN1 and AChE, reduces TNF-α expression and lipid peroxidation, demonstrating the potential of multi-target anti-Alzheimer's disease (AD)[1][2].
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L-Citronellol | 99.84% | L-Citronellol ((S)-3,7-Dimethyloct-6-en-1-ol) is a natural product with anti-allergic and neuroprotective effects. L-Citronellol inhibits mast cell activation and the release of inflammatory factors by inhibiting the ERK pathway. L-Citronellol inhibits BACE1/PSEN1 and AChE, reduces TNF-α expression and lipid peroxidation, demonstrating the potential of multi-target anti-Alzheimer's disease (AD). | ||||||||||||||||||||
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L-Citronellol (Standard) | 99.53% | L-Citronellol ((S)-3,7-Dimethyloct-6-en-1-ol) is an analytical standard for L-Citronellol (HY-W015515). This product is intended for research and analytical applications. L-Citronellol is a natural product with anti-allergic and neuroprotective effects. L-Citronellol inhibits mast cell activation and the release of inflammatory factors by inhibiting the ERK pathway. L-Citronellol inhibits BACE1/PSEN1 and AChE, reduces TNF-α expression and lipid peroxidation, demonstrating the potential of multi-target anti-Alzheimer's disease (AD). | ||||||||||||||||||||
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References
- [1]. Zhou J, et al. Natural compounds for Alzheimer's prevention and treatment: Integrating SELFormer-based computational screening with experimental validation. Comput Biol Med. 2025 Feb;185:109523. [Content Brief]
- [2]. Kobayashi Y, et al. Inhibitory effects of geranium essential oil and its major component, citronellol, on degranulation and cytokine production by mast cells. Biosci Biotechnol Biochem. 2016 Jun;80(6):1172-8. [Content Brief]
