3054220-62-8
3054220-62-8
Chemical Structure
PSEN1-IN-1
- CAS No.: 3054220-62-8
- Formula:C20H19ClF3NO3S
- Molecular Weight:445.88
InChIKey: POFWBCMHDKEJDR-WZGPROSRSA-N
SMILES: FC(F)(C1=CC=C([C@H]([C@@H]2CC3)N(S(C4=CC=C(Cl)C=C4)(=O)=O)[C@@H]3C[C@@H]2O)C=C1)F
Biological Activity: PSEN1-IN-1 (Compound (+)-13b) is a PSEN1 inhibitor. PSEN1-IN-1 inhibits PSEN1-APH1A and PSEN1-APH1B complex with IC50s of 19 and 5.5 nM. PSEN1-IN-1 can be used for Alzheimer's disease research[1].
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PSEN1-IN-1 | PSEN1-IN-1 (Compound (+)-13b) is a PSEN1 inhibitor. PSEN1-IN-1 inhibits PSEN1-APH1A and PSEN1-APH1B complex with IC50s of 19 and 5.5 nM. PSEN1-IN-1 can be used for Alzheimer's disease research. | |||||||||||||||||||||
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