PSEN1-IN-1
PSEN1-IN-1 (Compound (+)-13b) is a PSEN1 inhibitor. PSEN1-IN-1 inhibits PSEN1-APH1A and PSEN1-APH1B complex with IC50s of 19 and 5.5 nM. PSEN1-IN-1 can be used for Alzheimer's disease research.
For research use only. We do not sell to patients.
- CAS No.: 3054220-62-8
- Formula: C20H19ClF3NO3S
- Molecular Weight:445.88
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
19 and 5.5 nM for PSEN1-APH1A and PSEN1-APH1B complex[1]
Chemical Information
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CAS No. 3054220-62-8
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Molecular Weight 445.88
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Formula C20H19ClF3NO3S
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SMILES
FC(F)(C1=CC=C([C@H]([C@@H]2CC3)N(S(C4=CC=C(Cl)C=C4)(=O)=O)[C@@H]3C[C@@H]2O)C=C1)F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)