6 Results for "

Pirfenidone

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "Pirfenidone" in MCE Product Catalog:

92
92 Cited Publications
Cat. No.: HY-B0673
CAS No.: 53179-13-8
Synonyms: AMR69
Target:  

TGF-beta/Smad CCR

Research Areas:  

Inflammation/Immunology Cancer

Pirfenidone (AMR69) is an antifibrotic agent that attenuates CCL2 and CCL12 production in fibrocyte cells. Pirfenidone has growth-inhibitory effect and reduces TGF-β2 protein levels in human glioma cell lines. Pirfenidone also has anti-inflammatory activities .
loading...
    loading...
Cat. No.: HY-B0673R
CAS No.: 53179-13-8
Synonyms: AMR69 (Standard)
Pirfenidone (Standard) is the analytical standard of Pirfenidone. This product is intended for research and analytical applications. Pirfenidone (AMR69) is an antifibrotic agent that attenuates CCL2 and CCL12 production in fibrocyte cells. Pirfenidone has growth-inhibitory effect and reduces TGF-β2 protein levels in human glioma cell lines. Pirfenidone also has anti-inflammatory activities .
loading...
    loading...
Cat. No.: HY-B0673S
CAS No.: 1020719-62-3
Synonyms: AMR69-d5
Pirfenidone-d5 (AMR69-d5) is a deuterium labeled Pirfenidone. Pirfenidone is an antifibrotic agent that attenuates CCL2 and CCL12 production in fibrocyte cells. Pirfenidone has growth-inhibitory effect and reduces TGF-β2 protein levels in human glioma cell lines. Pirfenidone also has anti-inflammatory activities .
loading...
    loading...
Cat. No.: HY-B0673S1
CAS No.: 1093951-85-9
Synonyms: LYT-100; AMR69-d3
Deupirfenidone-d3 is the deuterium labeled Pirfenidone (HY-B0673). Pirfenidone (AMR69) is an antifibrotic agent that attenuates CCL2 and CCL12 production in fibrocyte cells. Pirfenidone has growth-inhibitory effect and reduces TGF-β2 protein levels in human glioma cell lines. Pirfenidone also has anti-inflammatory activities .
loading...
    loading...
Cat. No.: HY-160851
CAS No.: 1590403-33-0
Synonyms: AK3287; AKEX0011
Target:  

ASK1 p38 MAPK

Research Areas:  

Inflammation/Immunology

GDC-3280 (AK3287; AKEX0011) is an orally active compound based on Pirfenidone (HY-B0673)'s phenyl pyridone scaffold. GDC-3280 alleviates the inflammatory and fibrotic reaction of silicosis by inhibiting the ASK1-p38 MAPK pathway and regulating macrophage polarization. GDC-3280 exhibits anti-inflammatory and anti-fibrotic effects .
loading...
    loading...
Cat. No.: HY-144546S
CAS No.: 1020719-52-1
Synonyms: Pirfenidone Impurity 6-d5
5-(Hydroxymethyl)-1-phenylpyridin-2(1H)-one-d5 (Pirfenidone Impurity 6-d5) is the deuterium labeled 5-(Hydroxymethyl)-1-phenylpyridin-2(1H)-one (HY-W349458).
loading...
    loading...