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Plasmin Substrate

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amino Acid Derivatives (1) Factor Xa (1) Fluorescent Dye (11) Kallikrein (1) PAI-1 (4) Ser/Thr Protease (2) Thrombin (1)
By Research Areas:	Cardiovascular Disease (2)

Inhibitors & Agonists

Fluorescent Dyes

Peptides

Targets Recommended: Plasminogen/Plasmin MARCKS

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P2373

Kinase, Natto fermentation 4 Publications Verification	PAI-1	Cardiovascular Disease
Kinase, Natto fermentation is a potent fibrinolytic enzyme. Kinase, Natto fermentation can break down blood clots by directly hydrolyzing fibrin and plasmin substrate. Kinase, Natto fermentation can be used for the research of cardiovascular diseases .

HY-131409

D-Val-Leu-Lys-pNA dihydrochloride D-Val-Leu-Lys-p-itoailide dihydrochloride; D-VLK-pNA dihydrochloride; S 2251 dihydrochloride	Fluorescent Dye	Others
D-Val-Leu-Lys-pNA (D-Val-Leu-Lys-p-nitroanilide) dihydrochloride is a chromogenic peptide substrate that serves as a characteristic substrate for *plasmin* and plasminogen. D-Val-Leu-Lys-pNA dihydrochloride acts as a sensitive substrate for the DFE27 serine protease derived from Bacillus subtilis DC27. Catalyzed by plasmin, D-Val-Leu-Lys-pNA dihydrochloride binds and hydrolyzes to release p-nitroaniline (pNA), which can be detected colorimetrically at 405 nm as a measure of fibrinolytic activity .

HY-P4319

Boc-Glu-Lys-Lys-AMC	Fluorescent Dye	Others
Boc-Glu-Lys-Lys-AMC is a sensitive fluorogenic substrate for urokinase-activated plasmin .

HY-P4310

Boc-Val-Leu-Lys-AMC	Ser/Thr Protease	Others
Boc-Val-Leu-Lys-AMC is a sensitive, fluorogenic, and specific substrate of plasmin, as well as acrosin from the ascidian Halocynthia roretzi, porcine calpain isozymes I and II, and papain .

HY-P4341A

D-Val-Leu-Lys-AMC TFA	PAI-1 Fluorescent Dye	Others
D-Val-Leu-Lys-AMC TFA is a selective fluorogenic peptide substrate of *plasmin. D-Val-Leu-Lys-AMC TFA can be used for the quantification of enzymatic activity of plasmin*. Ex: 360-380 nm, Em: 440-460 nm .

HY-P4360

Suc-Ala-Phe-Lys-AMC	Fluorescent Dye	Others
Suc-Ala-Phe-Lys-AMC is a highly sensitive fluorogenic substrate for plasmin. Suc-Ala-Phe-Lys-AMC is also used for assaying gingipain K .

HY-P5027

Cbz-Lys-Arg-pNA	Ser/Thr Protease Kallikrein Factor Xa Thrombin	Cardiovascular Disease
Cbz-Lys-Arg-pNA is a peptide substrate containing pNA as the chromogenic group. Cbz-Lys-Arg-pNA is widely used in enzymatic analysis, including thrombin, *plasmin, factor Xa* and Kallikrein .

HY-P4341

D-Val-Leu-Lys-AMC	PAI-1 Fluorescent Dye	Others
D-Val-Leu-Lys-AMC is a selective fluorogenic peptide substrate of *plasmin. D-Val-Leu-Lys-AMC can be used for the quantification of enzymatic activity of plasmin*. Ex: 360-380 nm, Em: 440-460 nm .

HY-P5356

H-D-Val-Leu-Lys-AFC Plasmin Substrate	Fluorescent Dye	Others
H-D-Val-Leu-Lys-AFC (Plasmin substrate) is a biological active peptide. (This is a fluorescent plasmin substrate, Abs/Em=380/500 nm.Plasmin belongs to the family of serine proteases. It plays a key role in fibrinolysis by dissolving fibrin in blood clots. Besides fibrinolysis, plasmin is also involved in such physiological and pathological processes as wound healing, liver repair, and the maintenance of liver homeostasis.)

HY-137798

Chromozym PL	Fluorescent Dye	Others
Chromozym PL is a chromogenic substrate for plasmin, and the enzymatic reaction can be carried out in 0.1mL Tris-HCl buffer (50 mM, pH 7.8). 100 μM Chromozym PL was dissolved and prepared. After adding the hydrolase, the generation of p-nitroaniline (pNA) at 405 nm was continuously observed, and the hydrolysis products were calculated .

HY-P4347

MeOSuc-Ala-Phe-Lys-AMC TFA	Amino Acid Derivatives	Others
MeOSuc-Ala-Phe-Lys-AMC TFA is a peptide substrate of plasmin .

HY-138152

Z-D-Arg-Gly-Arg-pNA dihydrochloride Benzyl-D-Arg-Gly-Arg-pNA dihydrochloride	Fluorescent Dye	Others
Z-D-Arg-Gly-Arg-pNA dihydrochloride is a hydrolytic chromogenic plasmin substrate .

HY-P4339

Ala-Phe-Lys-AMC	Fluorescent Dye	Others
Ala-Phe-Lys-AMC is a fluorogenic substrate, which can be used for residual plasmin activity assay .

HY-168378

D-Val-Leu-Lys-pNA S-2251	Fluorescent Dye	Others
D-Val-Leu-Lys-pNA (S-2251) is a chromogenic peptide substrate that serves as a characteristic substrate for *plasmin* and plasminogen. D-Val-Leu-Lys-pNA acts as a sensitive substrate for the DFE27 serine protease derived from Bacillus subtilis DC27. Catalyzed by plasmin, D-Val-Leu-Lys-pNA binds and hydrolyzes to release p-nitroaniline (pNA), which can be detected colorimetrically at 405 nm as a measure of fibrinolytic activity .

HY-168378A

D-Val-Leu-Lys-pNA acetate S-2251 acetate	Fluorescent Dye	Others
D-Val-Leu-Lys-pNA acetate (S-2251 acetate) is a chromogenic peptide substrate that serves as a characteristic substrate for *plasmin* and plasminogen. D-Val-Leu-Lys-pNA acetate acts as a sensitive substrate for the DFE27 serine protease derived from Bacillus subtilis DC27. Catalyzed by plasmin, D-Val-Leu-Lys-pNA acetate binds and hydrolyzes to release p-nitroaniline (pNA), which can be detected colorimetrically at 405 nm as a measure of fibrinolytic activity .

HY-114150B

D-Val-Leu-Arg-pNA hydrochloride	PAI-1	Others
D-Val-Leu-Arg-pNA hydrochloride is a substrate for glandular kinin-releasing enzymes. D-Val-Leu-Arg-pNA hydrochloride can be used to determine the activities of plasminogen activator and plasmin. D-Val-Leu-Arg-pNA hydrochloride is also used to study the fibrinolytic activity of various organisms, such as bacteria and worms .

Cat. No.	Product Name	Type

HY-131409

D-Val-Leu-Lys-pNA dihydrochloride D-Val-Leu-Lys-p-itoailide dihydrochloride; D-VLK-pNA dihydrochloride; S 2251 dihydrochloride	Fluorescent Dyes
D-Val-Leu-Lys-pNA (D-Val-Leu-Lys-p-nitroanilide) dihydrochloride is a chromogenic peptide substrate that serves as a characteristic substrate for *plasmin* and plasminogen. D-Val-Leu-Lys-pNA dihydrochloride acts as a sensitive substrate for the DFE27 serine protease derived from Bacillus subtilis DC27. Catalyzed by plasmin, D-Val-Leu-Lys-pNA dihydrochloride binds and hydrolyzes to release p-nitroaniline (pNA), which can be detected colorimetrically at 405 nm as a measure of fibrinolytic activity .

D-Val-Leu-Lys-pNA dihydrochloride

D-Val-Leu-Lys-p-itoailide dihydrochloride; D-VLK-pNA dihydrochloride; S 2251 dihydrochloride

Fluorescent Dyes

D-Val-Leu-Lys-pNA (D-Val-Leu-Lys-p-nitroanilide) dihydrochloride is a chromogenic peptide substrate that serves as a characteristic substrate for plasmin and plasminogen. D-Val-Leu-Lys-pNA dihydrochloride acts as a sensitive substrate for the DFE27 serine protease derived from Bacillus subtilis DC27. Catalyzed by plasmin, D-Val-Leu-Lys-pNA dihydrochloride binds and hydrolyzes to release p-nitroaniline (pNA), which can be detected colorimetrically at 405 nm as a measure of fibrinolytic activity .

Cat. No.	Product Name	Target	Research Area

HY-131409

D-Val-Leu-Lys-pNA dihydrochloride D-Val-Leu-Lys-p-itoailide dihydrochloride; D-VLK-pNA dihydrochloride; S 2251 dihydrochloride	Fluorescent Dye	Others
D-Val-Leu-Lys-pNA (D-Val-Leu-Lys-p-nitroanilide) dihydrochloride is a chromogenic peptide substrate that serves as a characteristic substrate for *plasmin* and plasminogen. D-Val-Leu-Lys-pNA dihydrochloride acts as a sensitive substrate for the DFE27 serine protease derived from Bacillus subtilis DC27. Catalyzed by plasmin, D-Val-Leu-Lys-pNA dihydrochloride binds and hydrolyzes to release p-nitroaniline (pNA), which can be detected colorimetrically at 405 nm as a measure of fibrinolytic activity .

HY-P4319

Boc-Glu-Lys-Lys-AMC	Fluorescent Dye	Others
Boc-Glu-Lys-Lys-AMC is a sensitive fluorogenic substrate for urokinase-activated plasmin .

HY-P4310

Boc-Val-Leu-Lys-AMC	Ser/Thr Protease	Others
Boc-Val-Leu-Lys-AMC is a sensitive, fluorogenic, and specific substrate of plasmin, as well as acrosin from the ascidian Halocynthia roretzi, porcine calpain isozymes I and II, and papain .

HY-P4341A

D-Val-Leu-Lys-AMC TFA	PAI-1 Fluorescent Dye	Others
D-Val-Leu-Lys-AMC TFA is a selective fluorogenic peptide substrate of *plasmin. D-Val-Leu-Lys-AMC TFA can be used for the quantification of enzymatic activity of plasmin*. Ex: 360-380 nm, Em: 440-460 nm .

HY-P4360

Suc-Ala-Phe-Lys-AMC	Fluorescent Dye	Others
Suc-Ala-Phe-Lys-AMC is a highly sensitive fluorogenic substrate for plasmin. Suc-Ala-Phe-Lys-AMC is also used for assaying gingipain K .

HY-P5027

Cbz-Lys-Arg-pNA	Ser/Thr Protease Kallikrein Factor Xa Thrombin	Cardiovascular Disease
Cbz-Lys-Arg-pNA is a peptide substrate containing pNA as the chromogenic group. Cbz-Lys-Arg-pNA is widely used in enzymatic analysis, including thrombin, *plasmin, factor Xa* and Kallikrein .

HY-P4341

D-Val-Leu-Lys-AMC	PAI-1 Fluorescent Dye	Others
D-Val-Leu-Lys-AMC is a selective fluorogenic peptide substrate of *plasmin. D-Val-Leu-Lys-AMC can be used for the quantification of enzymatic activity of plasmin*. Ex: 360-380 nm, Em: 440-460 nm .

HY-P5356

H-D-Val-Leu-Lys-AFC Plasmin Substrate	Fluorescent Dye	Others
H-D-Val-Leu-Lys-AFC (Plasmin substrate) is a biological active peptide. (This is a fluorescent plasmin substrate, Abs/Em=380/500 nm.Plasmin belongs to the family of serine proteases. It plays a key role in fibrinolysis by dissolving fibrin in blood clots. Besides fibrinolysis, plasmin is also involved in such physiological and pathological processes as wound healing, liver repair, and the maintenance of liver homeostasis.)

HY-137798

Chromozym PL	Fluorescent Dye	Others
Chromozym PL is a chromogenic substrate for plasmin, and the enzymatic reaction can be carried out in 0.1mL Tris-HCl buffer (50 mM, pH 7.8). 100 μM Chromozym PL was dissolved and prepared. After adding the hydrolase, the generation of p-nitroaniline (pNA) at 405 nm was continuously observed, and the hydrolysis products were calculated .

HY-P4402

D-Ile-Phe-Lys-pNA	Peptides	Others
D-Ile-Phe-Lys-pNA is a highly specific substrate for human plasmin .

HY-P4347

MeOSuc-Ala-Phe-Lys-AMC TFA	Amino Acid Derivatives	Others
MeOSuc-Ala-Phe-Lys-AMC TFA is a peptide substrate of plasmin .

HY-138152

Z-D-Arg-Gly-Arg-pNA dihydrochloride Benzyl-D-Arg-Gly-Arg-pNA dihydrochloride	Fluorescent Dye	Others
Z-D-Arg-Gly-Arg-pNA dihydrochloride is a hydrolytic chromogenic plasmin substrate .

HY-P4339

Ala-Phe-Lys-AMC	Fluorescent Dye	Others
Ala-Phe-Lys-AMC is a fluorogenic substrate, which can be used for residual plasmin activity assay .

HY-168378A

D-Val-Leu-Lys-pNA acetate S-2251 acetate	Fluorescent Dye	Others
D-Val-Leu-Lys-pNA acetate (S-2251 acetate) is a chromogenic peptide substrate that serves as a characteristic substrate for *plasmin* and plasminogen. D-Val-Leu-Lys-pNA acetate acts as a sensitive substrate for the DFE27 serine protease derived from Bacillus subtilis DC27. Catalyzed by plasmin, D-Val-Leu-Lys-pNA acetate binds and hydrolyzes to release p-nitroaniline (pNA), which can be detected colorimetrically at 405 nm as a measure of fibrinolytic activity .

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