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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
REV7
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "REV7" in MCE Product Catalog:
4
4 Cited Publications
Target:
Research Areas:
JH-RE-06, a potent REV1-REV7 interface inhibitor (IC50=0.78 μM; Kd=0.42 μM), targets REV1 that interacts with the REV7 subunit of POLζ. JH-RE-06 disrupts mutagenic translesion synthesis (TLS) by preventing recruitment of mutagenic POLζ. JH-RE-06 improves chemotherapy .
1
1 Cited Publications
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Research Areas:
REV7/REV3L-IN-1 is a REV7/REV3L interaction inhibitor with an IC50 of 78 μM. REV7/REV3L-IN-1 binds directly to REV7 and inhibits its interaction with REV3L. REV7/REV3L-IN-1 inhibits interstrand crosslink repair in cells. REV7/REV3L-IN-1 chemosensitizes cancer cells to Cisplatin (HY-17394). REV7/REV3L-IN-1 can be used in cervical cancer research .
1
1 Cited Publications
Cat. No.: HY-P71540
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: MAD2L1; Mitotic Arrest Deficient 2-Like Protein 1; Mitotic Arrest Deficient 2 Like 1; MAD2-Like Protein 1; MAD2; Mitotic Arrest Deficient, Yeast, Homolog-Like 1; HSMAD2; MAD2 Mitotic Arrest Deficient-Like 1; MAD2 (Mitotic Arrest Deficient, Yeast, Homolog)
Species:
Human
Source:
E. coli
Cat. No.: HY-126214S
Purity: 98.04%
Cat. No.: HY-100468R
CAS No.: 1979192-13-6
Target:
Research Areas:
REV7/REV3L-IN-1 (Standard) is the analytical standard of REV7/REV3L-IN-1 (HY-100468). This product is intended for research and analytical applications. REV7/REV3L-IN-1 is a REV7/REV3L interaction inhibitor with an IC50 of 78 μM. REV7/REV3L-IN-1 binds directly to REV7 and inhibits its interaction with REV3L. REV7/REV3L-IN-1 inhibits interstrand crosslink repair in cells. REV7/REV3L-IN-1 chemosensitizes cancer cells to Cisplatin (HY-17394). REV7/REV3L-IN-1 can be used in cervical cancer research .
Cat. No.: HY-RS07951
Target:
Research Areas:
MAD2L2 Human Pre-designed siRNA Set A contains three designed siRNAs for MAD2L2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS19788
Target:
Research Areas:
Mad2l2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Mad2l2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P810361
Synonyms: Homolog of REV7 S ceREVisiae, hREV7, MAD2 (mitotic arrest deficient yeast, homolog) like 2, MAD2 homolog, MAD2 like 2, MAD2 mitotic arrest deficient like 2, MAD2-like protein 2, MAD2B, Mad2l2, MD2L2_HUMAN
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
