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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
44 Results for "
SM/Chol LUVs
" in MedChemExpress (MCE) Product Catalog:
Products (44)
44 Results for "SM/Chol LUVs" in MCE Product Catalog:
1
1
1 Cited Publications
Cat. No.: HY-P75786
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: GBA1; Acid Beta-Glucosidase; Prev. GLUC; Glucocerebrosidase; Prev. GBA; Glucosylceramidase; D-Glucosyl-N-Acylsphingosine Glucohydrolase; Imiglucerase; Lysosomal Cholesterol Glycosyltransferase; Alglucerase; Lysosomal Acid Glucosylceramidase; Beta-GC; Chol
Synonyms: DC-Cholesterol hydrochloride
Cat. No.: HY-N16308
CAS No.: 3091879-77-2
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Cat. No.: HY-144007
CAS No.: 27321-96-6
Cat. No.: HY-D0142
CAS No.: 59572-10-0
Synonyms: SCH-10304
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Clonixin (SCH-10304) is an orally active non-steroidal anti-inflammatory agent (NSAID) that inhibits COX synthesis. Clonixin acts as a voltage-gated L-type calcium channel blocker, exerts vasodilatory effects by antagonizing Ca 2+ in vascular smooth muscle. Clonixin inhibits TGF-β, reduces lung coefficient, immune cell infiltration level, oxidative stress response, airway resistance, hydroxyproline content and collagen deposition. Clonixin can be used in research related to inflammation such as idiopathic pulmonary fibrosis and moderate to severe pain .
Synonyms: 3-Hexanoyl-NBD-Cholesterol
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3-C6-NBD-cholesterol is a fluorescent analog of Chol that can be used to measure the kinetics of membrane and intracellular trafficking .
Synonyms: ARO-AAT sodium
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Fazirsiran sodium is a second-generation RNAi agent. Fazirsiran sodium consistes of a cholesterol-conjugated RNAi trigger (chol-RNAi) to selectively degrade Alpha1-antitrypsin (AAT) mRNA by RNAi and a melittin-derived peptide conjugated to N-acetylgalactosamine (NAG) formulated as the excipient EX1 to promote endosomal escape of the chol-RNAi in hepatocytes . Fazirsiran sodium can be used in the study of Alpha-1 Antitrypsin Deficiency (AATD) liver disease. AATD is caused by mutations in the alpha-1 antitrypsin (SERPINA1) gene.
Cat. No.: HY-P4119
CAS No.: 863608-35-9
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Cat. No.: HY-N16290
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Cat. No.: HY-152901
CAS No.: 2106868-12-4
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Chol-N3 is a bioorthogonal-based chol probe. Chol-N3 can combine with super-resolution fluorescence microscopy (SRM), providing direct visualization of nanoscale lipid heterogeneity in the cell surface of resting living cells . Chol-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Cat. No.: HY-132604
CAS No.: 2175009-08-0
Synonyms: ARO-AAT
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Fazirsiran (ARO-AAT) is a second-generation RNAi agent. Fazirsiran consistes of a cholesterol-conjugated RNAi trigger (chol-RNAi) to selectively reduce Alpha1-antitrypsin (AAT) synthesis and a melittin-derived peptide conjugated to N-acetylgalactosamine (NAG) formulated as the excipient EX1 to promote endosomal escape of the chol-RNAi in hepatocytes . Fazirsiran can be used in the study of Alpha-1 Antitrypsin Deficiency (AATD) liver disease. Alpha-1 antitrypsin deficiency (AATD) is caused by mutations in the alpha-1 antitrypsin (SERPINA1) gene.
Cat. No.: HY-P11430
CAS No.: 290360-66-6
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Cat. No.: HY-159859
CAS No.: 191990-35-9
IZ-Chol (IZ-Cholesterol) is an ionizable cationic lipid containing cholesterol. IZ-Chol-LNPs is highly potential to effectively complex with DNA, and endosome escape mechanisms mediated by proton sponge effect .
Cat. No.: HY-149664
CAS No.: 137056-72-5
Synonyms: DC-Chol
Cat. No.: HY-125529
CAS No.: 184582-91-0
Synonyms: Chol-T
DMPAC-Chol (Chol-T) is used for liposome formation. DMPAC-Chol (Chol-T) liposomes exhibits great transfection effciencies .
Cat. No.: HY-112752
CAS No.: 219850-70-1
Cat. No.: HY-136869
CAS No.: 1027801-74-6
MHAPC-Chol, a cationic cholesterol, results in a high gene silencing effect via high cellular association. MHAPC-Chol delivers siRNA to the liver .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
