Gal-C4-Chol
Gal-C4-Chol is a glycosylated cholesterol derivative. Gal-C4-Chol can be used as a ligand for asialoglycoprotein receptors (ASGPR) to prepare Galactosylated (Gal) liposomes. Gal-C4-Chol can be used to prepare simple lipid-based nanoparticles.
For research use only. We do not sell to patients.
- CAS No.: 219850-70-1
- Formula: C40H69N3O7S
- Molecular Weight:736.06
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Chemical Information
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CAS No. 219850-70-1
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Molecular Weight 736.06
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Formula C40H69N3O7S
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SMILES
C[C@@]12[C@]3([H])[C@](CC=C1C[C@H](CC2)OC(NCCCCNC(CS[C@@H]4O[C@@H]([C@@H]([C@@H]([C@H]4O)O)O)CO)=N)=O)([H])[C@@]5([H])[C@](CC3)([C@@](CC5)([H])[C@H](C)CCCC(C)C)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Miller AD. Delivery of RNAi therapeutics: work in progress. Expert Rev Med Devices. 2013 Nov;10(6):781-811. [Content Brief]
[2]. Managit C, et al. Effect of galactose density on asialoglycoprotein receptor-mediated uptake of galactosylated liposomes. J Pharm Sci. 2005 Oct;94(10):2266-75. [Content Brief]
[3]. Kawakami S, et al. Biodistribution characteristics of mannosylated, fucosylated, and galactosylated liposomes in mice. Biochim Biophys Acta. 2000 Dec 15;1524(2-3):258-65. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)