(R)-Chol-TPP
Based on 1 publication(s) in Google Scholar
(R)-Chol-TPP a mitochondria targeting liposome ligand could be used in pH-redox responsive.
For research use only. We do not sell to patients.
- Purity : 95.85%
- Formula: C55H78BrO5P
- Molecular Weight:930.08
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) (R)-Chol-TPP
More
Biological Activity
Description
Chemical Information
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Appearance Solid
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Molecular Weight 930.08
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Formula C55H78BrO5P
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Color White to off-white
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SMILES
[H][C@]1([C@@H](CCCC(C)C)C)CC[C@]2([C@@]3(CC=C4C[C@H](OCCOCCOCCOC(CCC[P+](C5=CC=CC=C5)(C6=CC=CC=C6)C7=CC=CC=C7)=O)CC[C@@]4([C@]3(CC[C@]12C)[H])C)[H])[H].[Br-]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Publications (1)
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Journal Impact Factor
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Most Recent
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Mater Today Bio
Novel pH-responsive lipid nanoparticles deliver UA-mediated mitophagy and ferroptosis for osteoarthritis treatment. [Abstract]2025 Mar 21:32:101697. PMID: 40225130
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (107.52 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Ethanol : 50 mg/mL (53.76 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Protocols
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ROS/oxidative-stress fluorescent staining
ROS/oxidative-stress fluorescent staining uses cell-permeant fluorogenic probes that become fluorescent after oxidation inside cells or tissues; commonly used examples include DCFH-DA/DCFDA for broad cellular oxidant detection, DHE for superoxide-related signal detection, MitoSOX for mitochondrial superoxide-related signal detection, and CellROX probes for oxidative-stress-associated fluorescence readouts. The assay detects probe oxidation rather than a single ROS species unless the probe and analysis method have been chemically validated for that species. DCFH-DA enters cells, is deacetylated by intracellular esterases to DCFH, and produces fluorescent DCF after oxidation, so the readout is used as an operational measure of total cellular oxidative stress rather than a species-specific ROS measurement. DHE and MitoSOX can report superoxide-related oxidation, but red fluorescence alone can include non-specific ethidium-like oxidation products; HPLC or optimized spectral approaches are
Purity & Documentation
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Data Sheet (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Ethanol / DMSO | 1 mM | 1.0752 mL | 5.3759 mL | 10.7518 mL | 26.8794 mL |
| 5 mM | 0.2150 mL | 1.0752 mL | 2.1504 mL | 5.3759 mL | |
| 10 mM | 0.1075 mL | 0.5376 mL | 1.0752 mL | 2.6879 mL | |
| 15 mM | 0.0717 mL | 0.3584 mL | 0.7168 mL | 1.7920 mL | |
| 20 mM | 0.0538 mL | 0.2688 mL | 0.5376 mL | 1.3440 mL | |
| 25 mM | 0.0430 mL | 0.2150 mL | 0.4301 mL | 1.0752 mL | |
| 30 mM | 0.0358 mL | 0.1792 mL | 0.3584 mL | 0.8960 mL | |
| 40 mM | 0.0269 mL | 0.1344 mL | 0.2688 mL | 0.6720 mL | |
| 50 mM | 0.0215 mL | 0.1075 mL | 0.2150 mL | 0.5376 mL | |
| DMSO | 60 mM | 0.0179 mL | 0.0896 mL | 0.1792 mL | 0.4480 mL |
| 80 mM | 0.0134 mL | 0.0672 mL | 0.1344 mL | 0.3360 mL | |
| 100 mM | 0.0108 mL | 0.0538 mL | 0.1075 mL | 0.2688 mL |
(R)-Chol-TPP Related Classifications
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