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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
96 Results for "
SNAP
" in MedChemExpress (MCE) Product Catalog:
Products (96)
96 Results for "SNAP" in MCE Product Catalog:
8
Target:
研究分野:
S-Nitroso-N-acetyl-DL-penicillamine (SNAP) is a nitric oxide donor and acts as a stable inhibitor of platelet aggregation .
5
Target:
HT-2157 (SNAP 37889) is a selective, high-affinity, competitive antagonists of galanin-3 receptor (Gal3).
2
2 Cited Publications
Target:
研究分野:
SNAP 94847 hydrochloride is a novel, high affinity selective melanin-concentrating hormonereceptor1 (MCHR1) antagonist with (Ki= 2.2 nM, Kd=530 pM), it displays >80-fold and >500-fold selectivity over MCHα1A and MCHD2 receptors respectively. SNAP 94847 hydrochloride binds with high affinity to the mouse and rat MCHR1 with minimal cross-reactivity to other GPCR, ion channels, enzymes, and transporters .
2
2 Cited Publications
Target:
研究分野:
HaXS8 is a dimerizer that can promote a covalent and irreversible intracellular dimerization of HaloTag and SNAP-tagged proteins of interest. HaXS8 does not interfere with PI3K/mTOR signaling .
1
1 Cited Publications
Target:
研究分野:
(S)-SNAP5114 is a non-covalent murine GABA transporter inhibitor with blood-brain barrier penetration ability, which exhibits significant subtype-selective inhibitory activity against mGAT4 (pIC50=5.71, pKi=4.56), much higher than its effects on mGAT1, mGAT2 and mGAT3. (S)-SNAP5114 elevates extracellular GABA concentrations by blocking the GABA reuptake mechanism, thereby enhancing thalamus-specific GABAergic signaling and exerting potential neuromodulatory effects. (S)-SNAP5114 is widely used in studies related to epilepsy, neuropathic pain, anxiety and depression, and various neurodegenerative diseases .
1
1 Cited Publications
製品番号: HY-P73634
純度: ≥ 90%, as determined by reducing SDS-PAGE.
別名: SNAP25; SEC9; Prev. SNAP; Synaptosomal-Associated Protein, 25kDa; SNAP-25; SUP; Synaptosomal-Associated Protein 25; Synaptosomal-Associated 25 KDa Protein; DJ1068F16.2; Synaptosome Associated Protein 25kDa; BA416N4.2; Super Protein; RIC-4; DEE117; RIC4; C
Species:
Human
Source:
E. coli
製品番号: HY-W017776
CAS 番号: 674799-96-3
別名: SNAP-NH2
Target:
研究分野:
BG-NH2 (SNAP-NH2) is an O6-alkylguanine cofactor and an amine-terminated building block. BG-NH2 serves as a key intermediate for the synthesis of various functionalized SNAP-tag fluorescent/functional substrates .
製品番号: HY-E70094
Target:
研究分野:
T4 UvsX Recombinase helps initiate DNA replication on a double-stranded DNA template by catalyzing synapsis between the template and a homologous DNA single strand that serves as primer. T4 UvsX Recombinase greatly amplifies the snap-back (hairpin-primed) DNA synthesis that is catalyzed by the T4 DNA polymerase holoenzyme on linear, single-stranded DNA templates .
Target:
研究分野:
Alkyne-SNAP (compound 3) is an Alkyne-conjugated benzylguanine. The benzylguanine moiety reacts with the SNAP-tag, allowing irreversible and covalent labeling of SNAP fusion proteins with an additional alkyne functionality for further click chemistry conjugation .
製品番号: HY-131028
純度: ≥95.0%
別名: JF646 TFA
製品番号: HY-151646
純度: 99.59%
別名: Alkyne-PEG5-BG
Target:
研究分野:
Alkyne-PEG5-SNAP is a click chemistry reagent containing an alkyne group. Alkyne-PEG5-SNAP can alkyne conjugated benzylguanine (BG), the BG moiety reacts specifically and rapidly with SNAP-tag, a polypeptide protein tag, allowing irreversible and covalent labeling of SNAP fusion proteins with an additional alkyne functionality suitable for further conjugation . Alkyne-PEG5-SNAP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
製品番号: HY-P0065
CAS 番号: 868844-74-0
Target:
研究分野:
Acetyl octapeptide-1 is a competitive inhibitor of SNAP-25. Acetyl octapeptide-1 affects muscle contraction, thereby making the face (especially the forehead and periocular area) appear smoother and wrinkle-free. Acetyl octapeptide-1 can be used in research on muscle contraction and skincare products .
製品番号: HY-130736
CAS 番号: 1811539-32-8
別名: JF549, SE; JF549, NHS
Target:
研究分野:
BGN3 is a good substrate for the SNAP-tag ? and H 5 enzymes. The activities of SNAP-tag ? and H 5 enzymes on BGN3 are reasonable (IC50= 15.6 and 23.5 μM, respectively) . BGN3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
製品番号: HY-148958
CAS 番号: 471918-16-8
Target:
研究分野:
SNAP-Biotin is a cell-permeable SNAP-tag-targeted labeling reagent. SNAP-Biotin undergoes an irreversible covalent reaction with SNAP-tag to transfer biotin to the tag. SNAP-Biotin enables the detection of SNAP-tag fusion proteins via a streptavidin-HRP immunoblotting system and achieves biotinylation of SNAP-tag fusion proteins. SNAP-Biotin is applicable to triple-negative breast cancer-related research .
製品番号: HY-175417
VHL-SNAP2-5C is a PROTAC degrader targeting SNAP-tag fusion proteins, with an IC50 of 0.33 μM for binding to VHL. VHL-SNAP2-5C covalently binds to the SNAP-tag target at one end and recruits the VHL ubiquitin E3 ligase at the other end to form a ternary complex, thereby inducing proteasome-dependent ubiquitination and degradation of SNAP fusion proteins through its heterobifunctional structure. VHL-SNAP2-5C can be used in studies of protein homeostasis and degradation mechanisms .
製品番号: HY-D2965
CAS 番号: 1219603-04-9
別名: SPG1
製品番号: HY-D2994
CAS 番号: 2434651-49-5
別名: SNAP-MaP555
Target:
研究分野:
SPY555-BG (SNAP-MaP555) is a cell-permeable fluorescent dye for SNAP-tag labeling of HIV-1 Gag, which enables visualization of HIV-1 intercellular transmission via SNAPf. SPY555-BG relies on irreversible covalent binding to the active-site cysteine of the SNAPf tag fused to HIV-1 Gag .
製品番号: HY-101013
CAS 番号: 79032-48-7
別名: S-Nitroso-N-acetylpenicillamine
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
