VHL-SNAP2-5C
Based on 1 Customer Validation
VHL-SNAP2-5C is a SNAP-fusion protein PROTAC degrader basing on a self-labeling protein SNAP tag. VHL-SNAP2-5C by endogenous tagging enables the visualization and the selective depletion of a SNAP-fusion protein, such as CLCa andEGFP.
(Pink: SNAP fusion protein ligand (HY-W128709); Blue: VHL ligand (HY-112078); Black: linker (HY-Y1139)).
For research use only. We do not sell to patients.
- Purity: 99.98%
- Formula: C42H53ClN8O6S
- Molecular Weight:833.44
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All PROTACs Isoforms
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Biological Activity
Chemical Information
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Appearance Solid
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Molecular Weight 833.44
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Formula C42H53ClN8O6S
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Color White to off-white
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SMILES
O=C(NCC1=CC=C(COC2=NC(N)=NC(Cl)=C2)C=C1)CCCCCC(N[C@@H](C(C)(C)C)C(N3[C@H](C(N[C@H](C4=CC=C(C5=C(C)N=CS5)C=C4)C)=O)C[C@@H](O)C3)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 100 mg/mL (119.98 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.1998 mL | 5.9992 mL | 11.9985 mL | 29.9962 mL |
| 5 mM | 0.2400 mL | 1.1998 mL | 2.3997 mL | 5.9992 mL | |
| 10 mM | 0.1200 mL | 0.5999 mL | 1.1998 mL | 2.9996 mL | |
| 15 mM | 0.0800 mL | 0.3999 mL | 0.7999 mL | 1.9997 mL | |
| 20 mM | 0.0600 mL | 0.3000 mL | 0.5999 mL | 1.4998 mL | |
| 25 mM | 0.0480 mL | 0.2400 mL | 0.4799 mL | 1.1998 mL | |
| 30 mM | 0.0400 mL | 0.2000 mL | 0.3999 mL | 0.9999 mL | |
| 40 mM | 0.0300 mL | 0.1500 mL | 0.3000 mL | 0.7499 mL | |
| 50 mM | 0.0240 mL | 0.1200 mL | 0.2400 mL | 0.5999 mL | |
| 60 mM | 0.0200 mL | 0.1000 mL | 0.2000 mL | 0.4999 mL | |
| 80 mM | 0.0150 mL | 0.0750 mL | 0.1500 mL | 0.3750 mL | |
| 100 mM | 0.0120 mL | 0.0600 mL | 0.1200 mL | 0.3000 mL |
VHL-SNAP2-5C Related Classifications
HY-175417 Related Classifications
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