SNAP-fusion protein ligand-1

製品番号: HY-W128709 純度: 96.03%: Data Sheet SDS COA 取扱説明書
FAQs
Technical Support

SNAP-fusion protein ligand-1 (Compound 3) is a Ligand for Target Protein for PROTAC. SNAP-fusion protein ligand-1 can be used for synthesis of PROTAC VHL-SNAP2-5C (HY-175417).

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

SNAP-fusion protein ligand-1 構造式

CAS 番号 : 913817-45-5

容量	価格（税別）	在庫状況	数量
100 mg	$110	在庫あり	Estimated Time of Arrival: December 31
250 mg	$205	在庫あり	Estimated Time of Arrival: December 31
500 mg	$325	在庫あり	Estimated Time of Arrival: December 31
1 g		お問い合わせ
5 g		お問い合わせ

or バルクお問い合わせ

* アイテムを追加する前、数量をご選択ください

This product is a controlled substance and not for sale in your territory.

カスタマーレビュー

Based on 0 publication(s) in Google Scholar

おすすめ

•関連スクリーニングライブラリ:

•関連小分子:

•関連タンパク質:

生物活性
純度とドキュメンテーション
参考文献
カスタマーレビュー

製品説明

SNAP-fusion protein ligand-1 (Compound 3) is a Ligand for Target Protein for PROTAC. SNAP-fusion protein ligand-1 can be used for synthesis of PROTAC VHL-SNAP2-5C (HY-175417)^[1].

分子量

264.71

分子式

C₁₂H₁₃ClN₄O

CAS 番号

913817-45-5

Appearance

Solid

Color

Off-white to light brown

SMILES

NC1=NC(Cl)=CC(OCC2=CC=C(CN)C=C2)=N1

輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

4°C, stored under nitrogen, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)

溶剤 & 溶解度

体外:

DMSO : 35 mg/mL (132.22 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.7777 mL	18.8886 mL	37.7772 mL
5 mM	0.7555 mL	3.7777 mL	7.5554 mL
10 mM	0.3778 mL	1.8889 mL	3.7777 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molarity Calculator
Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

一般には略語で表示されます：C₁V₁ = C₂V₂

濃度 _（開始）

体積 _（開始）

濃度 _（終了）

体積 _（終了）

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

純度とドキュメンテーション

純度: 96.03%

Select Batch:

データシート (266 KB) SDS (393 KB)

COA (244 KB) HNMR (245 KB) LCMS (89 KB)

取扱説明書 (2659 KB)

参考文献

[1]. Pol SA, et al. Induced degradation of SNAP-fusion proteins. RSC Chem Biol. 2024 Oct 21;5(12):1232–47. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.7777 mL	18.8886 mL	37.7772 mL	94.4430 mL
	5 mM	0.7555 mL	3.7777 mL	7.5554 mL	18.8886 mL
	10 mM	0.3778 mL	1.8889 mL	3.7777 mL	9.4443 mL
	15 mM	0.2518 mL	1.2592 mL	2.5185 mL	6.2962 mL
	20 mM	0.1889 mL	0.9444 mL	1.8889 mL	4.7221 mL
	25 mM	0.1511 mL	0.7555 mL	1.5111 mL	3.7777 mL
	30 mM	0.1259 mL	0.6296 mL	1.2592 mL	3.1481 mL
	40 mM	0.0944 mL	0.4722 mL	0.9444 mL	2.3611 mL
	50 mM	0.0756 mL	0.3778 mL	0.7555 mL	1.8889 mL
	60 mM	0.0630 mL	0.3148 mL	0.6296 mL	1.5740 mL
	80 mM	0.0472 mL	0.2361 mL	0.4722 mL	1.1805 mL
	100 mM	0.0378 mL	0.1889 mL	0.3778 mL	0.9444 mL