BG-NH2
Based on 1 Customer Validation
BG-NH2 (SNAP-NH2) is an O6-alkylguanine cofactor and an amine-terminated building block. BG-NH2 serves as a key intermediate for the synthesis of various functionalized SNAP-tag fluorescent/functional substrates.
For research use only. We do not sell to patients.
- Purity : 99.13%
- CAS No.: 674799-96-3
- Formula: C13H14N6O
- Molecular Weight:270.30
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Description
In Vitro
BG-NH2 and its derivatives undergo specific, covalent reactions with SNAP-tag proteins or SNAPR ribozymes. Since the amino group on BG-NH2 serves as a universal conjugation site, researchers can conveniently conjugate any molecule containing an NHS ester or other amine-reactive group (such as fluorescent dyes of different wavelengths, biotin, crosslinkers, click chemistry handles, etc.) to it, thus rapidly constructing a large library of SNAP-tag/SNAPR substrates[1][2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS No. 674799-96-3
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Appearance Solid
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Molecular Weight 270.30
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Formula C13H14N6O
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Color White to off-white
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SMILES
NCC1=CC=C(COC2=NC(N)=NC3=C2NC=N3)C=C1
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Synonyms
SNAP-NH2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
In Vitro:
DMSO : 5 mg/mL (18.50 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (282 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.6996 mL | 18.4980 mL | 36.9959 mL | 92.4898 mL |
| 5 mM | 0.7399 mL | 3.6996 mL | 7.3992 mL | 18.4980 mL | |
| 10 mM | 0.3700 mL | 1.8498 mL | 3.6996 mL | 9.2490 mL | |
| 15 mM | 0.2466 mL | 1.2332 mL | 2.4664 mL | 6.1660 mL |
BG-NH2 Related Classifications
HY-W017776 Related Classifications
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Keywords
- BG-NH2
- 674799-96-3
- SNAP-NH2
- Drug Intermediate
- near-infrared fluorescent substrates
- O6-alkylguanine cofactor
- DBCO-functionalized benzylguanine cofactors
- ovarian adenocarcinoma
- breast adenocarcinoma
- AzNP-functionalized benzylguanine cofactors
- amine-terminated benzylguanine building block
- MTR1 (SNAPR) ribozyme
- SNAP-tag
- Inhibitor
- inhibitor
- inhibit