2080306-25-6
2080306-25-6
Chemical Structure
HaXS8
- CAS No.: 2080306-25-6
- Formula:C35H43ClF4N6O8
- Molecular Weight:787.20
IUPAC Name: N-(4-(((2-amino-9H-purin-6-yl)oxy)methyl)benzyl)-2-(4-((18-chloro-3,6,9,12-tetraoxaoctadecyl)oxy)-2,3,5,6-tetrafluorophenoxy)acetamide
InChIKey: OHHUCZCSUXJJFO-UHFFFAOYSA-N
SMILES: NC1=NC2=C(C(OCC3=CC=C(C=C3)CNC(COC4=C(C(F)=C(C(F)=C4F)OCCOCCOCCOCCOCCCCCCCl)F)=O)=N1)N=CN2
Biological Activity: HaXS8 is a dimerizer that can promote a covalent and irreversible intracellular dimerization of HaloTag and SNAP-tagged proteins of interest. HaXS8 does not interfere with PI3K/mTOR signaling[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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HaXS8 | 99.28% | HaXS8 is a dimerizer that can promote a covalent and irreversible intracellular dimerization of HaloTag and SNAP-tagged proteins of interest. HaXS8 does not interfere with PI3K/mTOR signaling. | ||||||||||||||||||||
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References
- [1]. Erhart D, et, al. Chemical development of intracellular protein heterodimerizers. Chem Biol. 2013 Apr 18; 20(4): 549-57. [Content Brief]
- [2]. Saha I, et, al. Dynamics of the HIV Gag Lattice Detected by Localization Correlation Analysis and Time-Lapse iPALM. Biophys J. 2020 Aug 4; 119(3): 581-592. [Content Brief]
Keywords
