Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
18 Results for "
SPF
" in MedChemExpress (MCE) Product Catalog:
Products (18)
18 Results for "SPF" in MCE Product Catalog:
Synonyms: (S)-PF-06873600
(S)-PF-06873600 it the S enantiomer of PF-06873600. PF-06873600 is a selective and orally bioavailable inhibitor of cyclin-dependent kinase (CDK).
Synonyms: (2R,5S)-PF-06651600
Target:
Research Areas:
(2R,5S)-Ritlecitinib (2R,5S)-PF-06651600) is a JAK3 inhibitor (IC50=144.8 nM) .
Cat. No.: HY-19985A
CAS No.: 1858291-14-1
(3S, 4S)-PF-06459988 is the S enantiomer of PF-06459988 with less active. PF-06459988 is a potent irreversible inhibitor of T790M mutant epidermal growth factor receptor (EGFR). PF-06459988 has excellent selectivity against EGFR wild-type while possessing a minimally reactive electrophile that reduces the propensity of off-target labeling .
Cat. No.: HY-10396A
CAS No.: 409369-54-6
Synonyms: (2R,3S)-PF 03491390; (2R,3S)-IDN-6556
Target:
Research Areas:
(2R,3S)-Emricasan ((2R,3S)-PF 03491390) is an isomer of Emricasan (HY-10396). Emricasan is an orally active and irreversible pan-caspase inhibitor. Emricasan inhibits Zika virus (ZIKV)-induced increases in caspase-3 activity and protected human cortical neural progenitors .
Cat. No.: HY-146617
CAS No.: 2768599-97-7
Target:
Research Areas:
GLS1 Inhibitor-4 (compound 41e) is a potent GLS1 inhibitor with an IC50 of 11.86 nM. GLS1 Inhibitor-4 shows antiproliferative activity, good metabolic stability, robust GLS1 binding affinity. GLS1 Inhibitor-4 blocks the glutamine metabolism and induce the production of ROS. GLS1 Inhibitor-4 induces apoptosis and shows antitumor activity .
Cat. No.: HY-RS17937
Target:
Research Areas:
Otc Mouse Pre-designed siRNA Set A contains three designed siRNAs for Otc gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-14433A
CAS No.: 1149727-65-0
Synonyms: (S)-PF-991
Target:
Research Areas:
(S)-PF-462991 is a direct-acting S1P1,5 agonist .
Cat. No.: HY-RS12607
Target:
Research Areas:
SEC14L2 Human Pre-designed siRNA Set A contains three designed siRNAs for SEC14L2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-169825
CAS No.: 2170558-28-6
Target:
Research Areas:
(S)-PF-04995274 is a partial agonist of the 5-hydroxytryptamine receptor 4 (5-HT4R) and is an isomer of PF-04995274 (HY-18137) .
Cat. No.: HY-12788A
Purity: 99.85%
Target:
Research Areas:
(S)-PF-04449613 is the left-handed isomer of PF-04449613 (HY-12788). PF-04449613 is a selective PDE9A inhibitor with an IC50 of 22 nM. PF-04449613 improves motor learning ability in a mouse model .
Synonyms: (s)-INCB8761
Target:
Research Areas:
(s)-PF-4136309 is the isomer of PF-4136309 (HY-13245), and can be used as an experimental control. PF-4136309 is a potent, selective, and orally bioavailable CCR2 antagonist, with IC50s of 5.2 nM, 17 nM and 13 nM for human, mouse and rat CCR2.
Cat. No.: HY-13100A
CAS No.: 928774-44-1
Target:
Research Areas:
(S)-PF 03716556 is a K+-competitive acid blocker with gastric acid pump inhibitory activity. (S)-PF 03716556 can be used to inhibit disease states mediated by acid pump inhibitory activity .
Cat. No.: HY-12584A
Synonyms: (S)-PF-05190457
Target:
Research Areas:
(S)-PF-5190457 ((S)-PF-05190457) is the S-enantiomer of PF-5190457 (HY-12584). PF-5190457 (PF-05190457) is a potent and selective ghrelin receptor inverse agonist with a pKi of 8.36 .
Cat. No.: HY-P700271
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: rHuBCAS2, His, N-T7; Pre-mRNA-Splicing Factor SPF27; Breast Carcinoma-Amplified Sequence 2; Spliceosome-Associated Protein SPF 27; BCAS2
Cat. No.: HY-100754BR
CAS No.: 1792180-79-0
Synonyms: (2R,5S)-PF-06651600 (Standard)
Target:
Research Areas:
(2R,5S)-Ritlecitinib (Standard) is the analytical standard of (2R,5S)-Ritlecitinib (HY-100754B). This product is intended for research and analytical applications. (2R,5S)-Ritlecitinib (2R,5S)-PF-06651600) is a JAK3 inhibitor (IC50=144.8 nM) .
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
