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  3. (3S,4S)-PF-06459988

(3S,4S)-PF-06459988 

Cat. No.: HY-19985A
Handling Instructions

(3S, 4S)-PF-06459988 is the S enantiomer of PF-06459988 with less active. PF-06459988 is a potent irreversible inhibitor of T790M mutant epidermal growth factor receptor (EGFR). PF-06459988 has excellent selectivity against EGFR wild-type while possessing a minimally reactive electrophile that reduces the propensity of off-target labeling.

For research use only. We do not sell to patients.

(3S,4S)-PF-06459988 Chemical Structure

(3S,4S)-PF-06459988 Chemical Structure

CAS No. : 1858291-14-1

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Based on 1 publication(s) in Google Scholar

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Description

(3S, 4S)-PF-06459988 is the S enantiomer of PF-06459988 with less active. PF-06459988 is a potent irreversible inhibitor of T790M mutant epidermal growth factor receptor (EGFR). PF-06459988 has excellent selectivity against EGFR wild-type while possessing a minimally reactive electrophile that reduces the propensity of off-target labeling[1].

IC50 & Target

EGFR[1]

Molecular Weight

431.88

Formula

C₁₉H₂₂ClN₇O₃

CAS No.
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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Product Name:
(3S,4S)-PF-06459988
Cat. No.:
HY-19985A
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