1. Epigenetics
    Stem Cell/Wnt
    JAK/STAT Signaling
  2. JAK
  3. (2R,5S)-Ritlecitinib

(2R,5S)-Ritlecitinib (Synonyms: (2R,5S)-PF-06651600)

Cat. No.: HY-100754B
Handling Instructions

(2R,5S)-Ritlecitinib ((2R,5S)-PF-06651600) is a potent and selective JAK3 inhibitor (IC50=144.8 nM) extracted from patent US20150158864A1, example 68.

For research use only. We do not sell to patients.

(2R,5S)-Ritlecitinib Chemical Structure

(2R,5S)-Ritlecitinib Chemical Structure

CAS No. : 1792180-79-0

Size Stock
100 mg   Get quote  
250 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Other Forms of (2R,5S)-Ritlecitinib:

Top Publications Citing Use of Products

View All JAK Isoform Specific Products:

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

(2R,5S)-Ritlecitinib ((2R,5S)-PF-06651600) is a potent and selective JAK3 inhibitor (IC50=144.8 nM) extracted from patent US20150158864A1, example 68[1].

IC50 & Target[1]

JAK3

144.8 nM (IC50)

Molecular Weight

285.34

Formula

C₁₅H₁₉N₅O

CAS No.

1792180-79-0

SMILES

C[[email protected]@H]1CC[[email protected]@H](CN1C(C=C)=O)NC2=C3C=CNC3=NC=N2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

(2R,5S)-Ritlecitinib(2R,5S)-PF-06651600JAKJanus kinaseInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email address *

Phone number *

 

Organization name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
(2R,5S)-Ritlecitinib
Cat. No.:
HY-100754B
Quantity:
MCE Japan Authorized Agent: