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Stemona

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Autophagy (2) Bacterial (1) Drug Derivative (1) Influenza Virus (1) NO Synthase (1) P-glycoprotein (1) p38 MAPK (2) Parasite (2) Reference Standards (2)
By Research Areas:	Cancer (3) Infection (3) Inflammation/Immunology (8) Neurological Disease (2)

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W018643

Ferulic acid methyl ester 1 Publications Verification Methyl ferulate	p38 MAPK Autophagy	Neurological Disease Inflammation/Immunology Cancer
Ferulic acid methyl ester (Methyl ferulate) is a derivative of ferulic acid, isolated from Stemona tuberosa, with anti-inflammatory and antioxidant properties . Ferulic acid methyl ester is a cell membrane and brain permeable compound, shows free radical scavenging ability, used in the research of neurodegenerative disorders . Ferulic acid methyl ester inhibits COX-2 expression, blocks p-p38 and p-JNK in primary bone marrow derived-macrophages .

HY-N0352

Tuberostemonine 1 Publications Verification	Parasite	Infection
Tuberostemonine is a stenine alkaloid that can be isolated from Stemona tuberosa and Stemona sessifolia. Tuberostemonine is an antimalarial agent that has inhibitory activity against Ferredoxin-NADP ⁺ reductases (FNRs) from Plasmodium falciparum (PfFNR). Tuberostemonine can reduce the number of citric acid-induced coughs in guinea pigs. Tuberostemonine decreases bronchoalveolar lavage fluid (BALF), neutrophil and macrophage infiltration and reduces peribronchial and perivascular inflammatory cell infiltration in mouse model of acute lung inflammation. Tuberostemonine has a level of activity as a feeding deterrent .

HY-N3753

Dihydropinosylvin	Others	Others
Dihydropinosylvin is a stilbenoid that can be found in Stemona collinsae .

HY-N3286

Methyl 4-O-feruloylquinate	Influenza Virus	Others
Methyl 4-O-feruloylquinate (4-O-Feruloylquinic acid methyl ester) is a natural product. Methyl 4-O-feruloylquinate can be purified from Stemona Japonica by preparative high-performance liquid chromatography. Methyl 4-O-feruloylquinate has anti-H5N1 activity with a 3% protective rate at 5 μM in MDCK cells .

HY-N3196

Neotuberostemonine	Bacterial	Infection Inflammation/Immunology
Neotuberostemonine, one of the main antitussive alkaloids in the root of Stemona tuberosa Lour, attenuates bleomycin-induced pulmonary fibrosis by suppressing the recruitment and activation of macrophages .

HY-N16597

Tuberostemonine A	Others	Others
Tuberostemonine A is a natural product that can be found in Stemona tuberosa .

HY-N16537

2-Oxostenine	NO Synthase	Inflammation/Immunology
2-Oxostenine (Compound 7) is a stenine-type alkaloid found in the roots of Stemona tuberosa Lour. 2-Oxostenine can weakly inhibit Lipopolysaccharide (HY-D1056)-induced NO production. 2-Oxostenine can be used for the research of inflammation .

HY-N16587

Dehydro-γ-tocopherol	Others	Inflammation/Immunology
Dehydro-γ-tocopherol is a naturally occurring chromanol compound found in the Stemona, and it exhibits significant antioxidant activity .

HY-N0352R

Tuberostemonine (Standard)	Reference Standards Parasite	Infection
Tuberostemonine (Standard) is the analytical standard of Tuberostemonine. This product is intended for research and analytical applications. Tuberostemonine is a stenine alkaloid that can be isolated from Stemona tuberosa and Stemona sessifolia. Tuberostemonine is an antimalarial agent that has inhibitory activity Ferredoxin-NADP ⁺ reductases (FNRs) from Plasmodium falciparum (PfFNR). Tuberostemonine has a level of activity as a feeding deterrent .

HY-N1955

Protostemotinine	Others	Inflammation/Immunology
Protostemotinine is an alkaloid isolated from the roots and rhizomes of Stemona sessilifolia.

HY-N3195

Neotuberostemonone	Others	Others
Neotuberostemonone is an alkaloid, that can be isolated from the roots of Stemona mairei (levl.) Krause .

HY-N3197

Neostenine (+)-Neostenine	P-glycoprotein	Cancer
Neostenine is a stenine-type Stemona alkaloid, with antitussive activity. Neostenine is also a substrate of P-glycoprotein with high absorptive permeability in Caco-2 monolayer model. Neostenine also shows oral activity for intestinal application .

HY-N9392

Stemonidine	Others	Others
Stemonidine is a natural Stemona alkaloid .

HY-W685091

Bisdehydrotuberostemonine	Others	Others
Bisdehydrotuberostemonine is an alkaloid found in the roots of Stemona sessilifolia .

HY-N13133

Tuberostemonine D	Others	Others
Tuberostemonine D, an alkaloid obtained, can be obtained from the root of Stemona tuberosa .

HY-N9014

Bisdehydroneotuberostemonine	Others	Others
Bisdehydroneotuberostemonine (Compound 4) is a kind of alkaloid. Bisdehydroneotuberostemonine is isolated from naturalStemona tuberosa .

HY-N18132

Stenine	Others	Others
Stenine (Compound 5) is an alkaloid found in the roots of Stemona sessilifolia .

HY-N18270

9α-epi-Tuberospironine A	Others	Others
9α-epi-Tuberospironine A is a croomine-type stemona alkaloid found in the roots of Stemona tuberosa .

HY-N18127

Oxystemoninine	Others	Others
Oxystemoninine is a Stemona alkaloid of the stemonamide type, which can be isolated from the roots of Stemona tuberosa. Oxystemoninine exhibits ¹H- and ¹³C-NMR spectra similar to those of stemoninine (HY-134006) .

HY-N18082

Croomine	Drug Derivative	Others
Croomine is a tuberostemospironine-type alkaloid. Croomine can be found in Stemona tuberosa, Croomia heterosepala, and Croomia japonica .

HY-N18266

10-Hydroxycroomine	Others	Inflammation/Immunology
10-Hydroxycroomine is a croomine-type alkaloid. 10-Hydroxycroomine can be isolated from the roots of Stemona tuberosa. 10-Hydroxycroomine produces a non-statistically significant reduction in Citric acid (HY-N1428)-induced coughing. 10-Hydroxycroomine can be used for the research of cough .

HY-N16978

Tuberospironine A	Others	Inflammation/Immunology
Tuberospironine A is a Stemona alkaloid compound; a series of Stemona alkaloids often exhibit pharmacological activities such as antitussive effects. Tuberospironine A can be naturally extracted from the dried roots of Stemona tuberosa Lour., which grows in Indonesia .

HY-N1199

Stilbostemin B	Others	Others
Stilbostemin B is a stilbenoid compound that can be found in Stemona species .

HY-N1298

Sessilifoline A	Others	Others
Sessilifoline A is a Alkaloids product that can be isolated from the roots of Stemona japonica .

HY-W018643R

Ferulic acid methyl ester (Standard) Methyl ferulate (Standard)	p38 MAPK Reference Standards Autophagy	Neurological Disease Inflammation/Immunology Cancer
Ferulic acid methyl ester (Standard) is the analytical standard of Ferulic acid methyl ester (HY-W018643). This product is intended for research and analytical applications. Ferulic acid methyl ester (Methyl ferulate) is a derivative of ferulic acid, isolated from Stemona tuberosa, with anti-inflammatory and antioxidant properties . Ferulic acid methyl ester is a cell membrane and brain permeable compound, shows free radical scavenging ability, used in the research of neurodegenerative disorders . Ferulic acid methyl ester inhibits COX-2 expression, blocks p-p38 and p-JNK in primary bone marrow derived-macrophages .

Ferulic acid methyl ester 1 Publications Verification Methyl ferulate	Monophenols Classification of Application Fields Neurological Disease Simple Phenylpropanols Stemonaceae Phenols Phenylpropanoids Plants Disease Research Fields Stemona tuberosa Lour. Cancer Source Classification	p38 MAPK Autophagy
Ferulic acid methyl ester (Methyl ferulate) is a derivative of ferulic acid, isolated from Stemona tuberosa, with anti-inflammatory and antioxidant properties . Ferulic acid methyl ester is a cell membrane and brain permeable compound, shows free radical scavenging ability, used in the research of neurodegenerative disorders . Ferulic acid methyl ester inhibits COX-2 expression, blocks p-p38 and p-JNK in primary bone marrow derived-macrophages .

Tuberostemonine 1 Publications Verification	Infection Alkaloids other families Pyrrole Alkaloids Classification of Application Fields Plants Disease Research Fields Source Classification	Parasite
Tuberostemonine is a stenine alkaloid that can be isolated from Stemona tuberosa and Stemona sessifolia. Tuberostemonine is an antimalarial agent that has inhibitory activity against Ferredoxin-NADP ⁺ reductases (FNRs) from Plasmodium falciparum (PfFNR). Tuberostemonine can reduce the number of citric acid-induced coughs in guinea pigs. Tuberostemonine decreases bronchoalveolar lavage fluid (BALF), neutrophil and macrophage infiltration and reduces peribronchial and perivascular inflammatory cell infiltration in mouse model of acute lung inflammation. Tuberostemonine has a level of activity as a feeding deterrent .

Dihydropinosylvin	Stemonaceae Phenols Polyphenols Plants Stemona collinsae Craib Source Classification	Others
Dihydropinosylvin is a stilbenoid that can be found in Stemona collinsae .

Methyl 4-O-feruloylquinate	Simple Phenylpropanols Stemonaceae Phenylpropanoids Plants Stemona japonica (Bl.) Miq Source Classification	Influenza Virus
Methyl 4-O-feruloylquinate (4-O-Feruloylquinic acid methyl ester) is a natural product. Methyl 4-O-feruloylquinate can be purified from Stemona Japonica by preparative high-performance liquid chromatography. Methyl 4-O-feruloylquinate has anti-H5N1 activity with a 3% protective rate at 5 μM in MDCK cells .

Neotuberostemonine	Alkaloids Classification of Application Fields Stemonaceae Plants Inflammation/Immunology Disease Research Fields Stemona tuberosa Lour. Indole Alkaloids Source Classification	Bacterial
Neotuberostemonine, one of the main antitussive alkaloids in the root of Stemona tuberosa Lour, attenuates bleomycin-induced pulmonary fibrosis by suppressing the recruitment and activation of macrophages .

Tuberostemonine A	Structural Classification Alkaloids Pyrrole Alkaloids Stemonaceae Plants Stemona tuberosa Lour. Source Classification	Others
Tuberostemonine A is a natural product that can be found in Stemona tuberosa .

2-Oxostenine	Structural Classification Alkaloids Stemonaceae Other Alkaloids Plants Stemona tuberosa Lour. Source Classification	NO Synthase
2-Oxostenine (Compound 7) is a stenine-type alkaloid found in the roots of Stemona tuberosa Lour. 2-Oxostenine can weakly inhibit Lipopolysaccharide (HY-D1056)-induced NO production. 2-Oxostenine can be used for the research of inflammation .

Dehydro-γ-tocopherol	Structural Classification Microorganisms Coumarins Phenylpropanoids Source Classification	Others
Dehydro-γ-tocopherol is a naturally occurring chromanol compound found in the Stemona, and it exhibits significant antioxidant activity .

Tuberostemonine (Standard)	Alkaloids Structural Classification other families Pyrrole Alkaloids Plants Source Classification	Reference Standards Parasite
Tuberostemonine (Standard) is the analytical standard of Tuberostemonine. This product is intended for research and analytical applications. Tuberostemonine is a stenine alkaloid that can be isolated from Stemona tuberosa and Stemona sessifolia. Tuberostemonine is an antimalarial agent that has inhibitory activity Ferredoxin-NADP ⁺ reductases (FNRs) from Plasmodium falciparum (PfFNR). Tuberostemonine has a level of activity as a feeding deterrent .

Protostemotinine	Alkaloids Pyrrole Alkaloids Classification of Application Fields Stemonaceae Plants Inflammation/Immunology Disease Research Fields Stemona sesslifolia Source Classification	Others
Protostemotinine is an alkaloid isolated from the roots and rhizomes of Stemona sessilifolia.

Neotuberostemonone	Alkaloids Stemonaceae Other Alkaloids Stemona mairei (Levl.) Krause Plants Source Classification	Others
Neotuberostemonone is an alkaloid, that can be isolated from the roots of Stemona mairei (levl.) Krause .

Neostenine (+)-Neostenine	Alkaloids Pyrrole Alkaloids Stemonaceae Other Alkaloids Plants Source Classification Stemona sesslifolia	P-glycoprotein
Neostenine is a stenine-type Stemona alkaloid, with antitussive activity. Neostenine is also a substrate of P-glycoprotein with high absorptive permeability in Caco-2 monolayer model. Neostenine also shows oral activity for intestinal application .

Stemonidine	Alkaloids Pyrrole Alkaloids Classification of Application Fields Stemonaceae Other Diseases Plants Disease Research Fields Source Classification Stemona japonica (Bl.) Miq	Others
Stemonidine is a natural Stemona alkaloid .

Bisdehydrotuberostemonine	Structural Classification Alkaloids Pyrrole Alkaloids Stemonaceae Stemona mairei (Levl.) Krause Plants Source Classification	Others
Bisdehydrotuberostemonine is an alkaloid found in the roots of Stemona sessilifolia .

Tuberostemonine D	Alkaloids Stemonaceae Other Alkaloids Plants Stemona tuberosa Lour. Source Classification	Others
Tuberostemonine D, an alkaloid obtained, can be obtained from the root of Stemona tuberosa .

Bisdehydroneotuberostemonine	Alkaloids Stemonaceae Other Alkaloids Plants Stemona tuberosa Lour. Source Classification	Others
Bisdehydroneotuberostemonine (Compound 4) is a kind of alkaloid. Bisdehydroneotuberostemonine is isolated from naturalStemona tuberosa .

Stenine	Structural Classification Alkaloids Pyrrole Alkaloids Stemonaceae Plants Stemona sesslifolia Source Classification	Others
Stenine (Compound 5) is an alkaloid found in the roots of Stemona sessilifolia .

9α-epi-Tuberospironine A	Structural Classification Alkaloids Pyrrole Alkaloids Stemonaceae Plants Stemona tuberosa Lour. Source Classification	Others
9α-epi-Tuberospironine A is a croomine-type stemona alkaloid found in the roots of Stemona tuberosa .

Oxystemoninine	Structural Classification Alkaloids Stemonaceae Other Alkaloids Plants Stemona japonica (Bl.) Miq Source Classification	Others
Oxystemoninine is a Stemona alkaloid of the stemonamide type, which can be isolated from the roots of Stemona tuberosa. Oxystemoninine exhibits ¹H- and ¹³C-NMR spectra similar to those of stemoninine (HY-134006) .

Croomine	Structural Classification Alkaloids Pyrrole Alkaloids Stemonaceae Plants Stemona tuberosa Lour. Source Classification	Drug Derivative
Croomine is a tuberostemospironine-type alkaloid. Croomine can be found in Stemona tuberosa, Croomia heterosepala, and Croomia japonica .

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