25 Results for "

Stereochemistry

" in MedChemExpress (MCE) Product Catalog:
Products (25)

25 Results for "Stereochemistry" in MCE Product Catalog:

6
6 Cited Publications
Cat. No.: HY-B1018A
CAS No.: 156-51-4
Phenelzine sulfate, an antidepressant agent, is an irreversible and orally active monoamine oxidase (MAO-A and MAO-B) inhibitor. Phenelzine sulfate inhibits GABA transaminase and primary amine oxidase (PrAO), and sequester reactive aldehydes. Phenelzine sulfate also inhibits LSD1 (Ki: 5.6 μM) and suppresses oxidative stress and lipogenesis. Phenelzine sulfate elevates neurotransmitters (serotonin, norepinephrine, dopamine). Phenelzine sulfate is studied in neurological, metabolic and cancer diseases for depression and anxiety disorders, stroke, spinal cord injury, traumatic brain injury, multiple sclerosis, Parkinson’s disease, Alzheimer’s disease, inflammatory pain, obesity and prostate cancer .
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Cat. No.: HY-137824
CAS No.: 6734-33-4
Purity:  99.70%
Synonyms: 4-Methylumbelliferyl-β-D-xyloside
4-Methylumbelliferyl-β-D-xylopyranoside (4-Methylumbelliferyl-β-D-xyloside) is an enzymatically hydrolyzable β-D-xylopyranoside substrate. The enzymatic hydrolysis of 4-Methylumbelliferyl-β-D-xylopyranoside is mediated by the stereochemistry-retaining β-D-xylosidase GSXynB2 via a two-step catalytic process (xylosylation followed by dexylosidation). 4-Methylumbelliferyl-β-D-xylopyranoside serves as a substrate for the β-xylosidase of Trichoderma reesei QM 9414, and its enzymatic hydrolysis process is limited by the dexylosidation step.
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Cat. No.: HY-126584
CAS No.: 3918-94-3
Purity:  ≥99.0%
Synonyms: Val-Val
Research Areas:  

Others

H-Val-Val-OH (Val-Val) is a stereochemistry-dependent substrate and inhibitor of apical oligopeptide transporters. H-Val-Val-OH undergoes apical intracellular accumulation in human intestinal cells via carrier-mediated transport, and inhibits the uptake of Cephalexin (HY-B0200) through interaction with transporters. Substitution of L-valine with D-valine in H-Val-Val-OH abolishes its binding ability to apical oligopeptide transporters .
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Cat. No.: HY-W010394
CAS No.: 30414-53-0
Methyl 3-oxopentanoate, which is also known as diethyl acetylmalonate or MEAM, Methyl 3-oxopentanoate is commonly used as a building block for the synthesis of various organic compounds, including pharmaceuticals, agrochemicals, and flavorings, and it can also Used as a reagent in organic chemical reactions, especially the formation of carbon-carbon bonds through malonate synthesis, the researchers also investigated the potential use of Methyl 3-oxopentanoate in the development of chiral auxiliaries that can aid in the selection of Controlling the stereochemistry of chemical reactions.
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Cat. No.: HY-120949
CAS No.: 109620-49-7
Purity:  99.14%
Target:  

Opioid Receptor

Research Areas:  

Neurological Disease

(1R,2R)-U-50488 hydrochloride is the absolute stereochemistry of (±)-U-50488 hydrochloride. (±)-U-50488 hydrochloride is a selective κ opioid receptor (KOR) agonist .
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Cat. No.: HY-175402
CAS No.: 276669-86-4
Target:  

Drug Isomer

Research Areas:  

Infection Inflammation/Immunology

(S)-5-Hydroxyequol is a (S)-stereochemistry of 5-Hydroxyequol. (S)-5-Hydroxyequol can be used for research on oxidative damage, fungal infections, inflammation, and immunosuppression .
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Cat. No.: HY-W039854
CAS No.: 13100-46-4
Synonyms: 1,2,3,4-Tetra-O-acetyl-beta-D-glucopyranose, 96%
1,2,3,4-Tetra-O-acetyl-β-D-glucopyranose, 96% (1,2,3,4-Tetra-O-acetyl-beta-D-glucopyranose, 96%) can be used in glycobiology research to study glycosylation mechanisms, glycosidic bond formation, and stereochemistry.
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Cat. No.: HY-W035375
CAS No.: 117342-78-6
Target:  

Drug Metabolite

Research Areas:  

Neurological Disease

Mephedrone metabolite hydrochloride ((±)-ephedrine stereochemistry) is a metabolite of Mephedrone.
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Cat. No.: HY-113801
CAS No.: 106983-27-1
Purity:  99.69%
Synonyms: (Rac)-3-oxo-C8-HSL
N-(3-Oxooctanoyl)-DL-homoserine lacton is a member of N-Acyl homoserine lactone (AHL) from gram-negative bacteria, with stereochemistry-dependent growth regulatory activity for roots .
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Cat. No.: HY-134775A
CAS No.: 1247001-86-0
Research Areas:  

Cancer

PLK4-IN-3 is a less active absolute stereochemistry of PLK4-IN-1. PLK4-IN-1 is a spiro cyclopropyl indolinone compound and PLK4 inhibitor with inhibitory activity against Aurora A and Aurora B kinases .PLK4-IN-1 can be used for the research of cancer .
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Cat. No.: HY-W144704B
CAS No.: 189302-44-1
(3RS, 7R, 11R)-Dihydrophytol is the hydrogenation intermediate in the synthesis of Phytanic acid (HY-113067) from Phytol (HY-N3075) .
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Cat. No.: HY-N12962
CAS No.: 123931-40-8
11S(12R)-EET is a dominant enantiomer of epoxytrienoic acid (EET) that is metabolized at a higher rate in rat organs. It shows enantiomeric-dependent reaction selectivity in hydration, especially in the case of 11,12-EET, where water addition is non-regioselective, while in 8,9-EET, water addition occurs mainly at the C9 position. In addition, 11S(12R)-EET generates diol products with specific stereochemistry through enzymatic hydration reactions, which are affected by the selective recognition of epoxidases, reaction conversion rates, and substrate binding parameters .
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Cat. No.: HY-137938
CAS No.: 65647-66-7
Radicinol is a metabolite of cochliobolus lunata, and absolute stereochemistry of radicinin .
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Cat. No.: HY-160983
CAS No.: 169736-88-3
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

PHYLPA-8 is an inhibitor for DNA polymerase-α, which exhibits weak inhibitory activity for the stereochemistry of the fatty acid moiety and the cyclic phosphate .
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Cat. No.: HY-117542
CAS No.: 16740-29-7
Research Areas:  

Neurological Disease

D595 is a phenylethylamine calcium channel blocker with potent negative inotropic activity. D595 has shown significant efficacy in its corresponding pharmacological studies, especially in inhibiting the uptake of monoamine neurotransmitters. D595 has high affinity in binding to the dopamine transporter (DAT), serotonin transporter (SERT), and norepinephrine transporter (NET). Structural adjustments of D595, especially changes in the hydroxyl stereochemistry, significantly affect its interaction with the transporters, showing a specific preference for stereoisomers .
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Cat. No.: HY-N15259
CAS No.: 172617-17-3
3'R-HBHL is a reference compound used for determining the stereochemistry of small bacteriocins .
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Cat. No.: HY-N21537
CAS No.: 83156-03-0
Angelol E is a coumarin found in the roots of Angelica pubescens Maxim. It contains an isovaleryl group, with the absolute configurations at positions C-11 and C-12 both being R. Angelol E can be used in studies related to natural product chemistry and coumarin stereochemistry .
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Cat. No.: HY-W720429
CAS No.: 73477-63-1
Target:  

Drug Metabolite

Research Areas:  

Metabolic Disease

2,5-Diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine is a metabolite in the biosynthesis pathway (purine metabolism process) of Riboflavin (HY-B0456) .
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Cat. No.: HY-172742
Research Areas:  

Others

Dioctanoyl PI(3,4)P2 (sodium) is a synthetic analog of natural Ptdlns featuring C8:0 fatty acids at the sn-1 and sn-2 positions. Dioctanoyl PI(3,4)P2 (sodium) contains the same inositol and diacylglycerol (DAG) stereochemistry as the natural Ptdlns .
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Cat. No.: HY-35034
CAS No.: 51576-04-6
Synonyms: (2S,3S)-2-Hydroxy-3-methylpentanoic acid
Research Areas:  

Others

L-Isoleucic acid ((2S,3S)-2-Hydroxy-3-methylpentanoic acid) ((S)-isoleucic acid) is a non-proteinogenic amino acid derivative. L-Isoleucic acid can be used as a key synthetic building block to construct JBIR-39 .
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