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Cat. No.: HY-160983

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PHYLPA-8

PHYLPA-8 is an inhibitor for DNA polymerase-α, which exhibits weak inhibitory activity for the stereochemistry of the fatty acid moiety and the cyclic phosphate.

For research use only. We do not sell to patients.

CAS No.: 169736-88-3
Formula: C₂₁H₃₈NaO₆P
Molecular Weight:440.49

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (261 KB)

PHYLPA-8 Chemical Structure

CAS No.: 169736-88-3

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

PHYLPA-8 is an inhibitor for DNA polymerase-α, which exhibits weak inhibitory activity for the stereochemistry of the fatty acid moiety and the cyclic phosphate^[1].

All DNA/RNA Synthesis Isoforms :

Chemical Information

CAS No. 169736-88-3
Molecular Weight 440.49
Formula C₂₁H₃₈NaO₆P
SMILES

CCCCCCCC/C=C\CCCCCCCC(OC[C@@H]1COP(O1)(O[Na])=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (261 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Murakami-Murofushi K, et al., Selective inhibition of DNA polymerase-alpha family with chemically synthesized derivatives of PHYLPA, a unique Physarum lysophosphatidic acid. Biochim Biophys Acta. 1995 Aug 24;1258(1):57-60. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
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Chemical Information
Purity & Documentation
References

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PHYLPA-8

All DNA/RNA Synthesis Isoforms