3918-94-3
Chemical Structure
H-Val-Val-OH
Synonym(s): Val-Val
- CAS No.: 3918-94-3
- Formula:C10H20N2O3
- Molecular Weight:216.28
IUPAC Name: L-valyl-L-valine
InChIKey: KRNYOVHEKOBTEF-YUMQZZPRSA-N
SMILES: CC(C)[C@@H](C(O)=O)NC([C@H](C(C)C)N)=O
Biological Activity: H-Val-Val-OH (Val-Val) is a stereochemistry-dependent substrate and inhibitor of apical oligopeptide transporters. H-Val-Val-OH undergoes apical intracellular accumulation in human intestinal cells via carrier-mediated transport, and inhibits the uptake of Cephalexin (HY-B0200) through interaction with transporters. Substitution of L-valine with D-valine in H-Val-Val-OH abolishes its binding ability to apical oligopeptide transporters[1].
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H-Val-Val-OH | 98.89% | H-Val-Val-OH (Val-Val) is a stereochemistry-dependent substrate and inhibitor of apical oligopeptide transporters. H-Val-Val-OH undergoes apical intracellular accumulation in human intestinal cells via carrier-mediated transport, and inhibits the uptake of Cephalexin (HY-B0200) through interaction with transporters. Substitution of L-valine with D-valine in H-Val-Val-OH abolishes its binding ability to apical oligopeptide transporters. | ||||||||||||||||||||
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Keywords
