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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
13 Results for "
TK1
" in MedChemExpress (MCE) Product Catalog:
Products (13)
13 Results for "TK1" in MCE Product Catalog:
Cat. No.: HY-W342664
CAS No.: 55612-21-0
Synonyms: FIRU
Target:
Research Areas:
2'-Deoxy-2'-fluoro-5-iodouridine (FIRU) is a nucleoside analog. When labeled with 123I, 2'-Deoxy-2'-fluoro-5-iodouridine accumulates highly selectively in tumors expressing the HSV1-tk gene. Radiolabeled 2'-Deoxy-2'-fluoro-5-iodouridine enables imaging of adenovirus-mediated HSV1-tk suicide gene transfer [1].
Synonyms: 2'-Deoxy-2'-fluoro-5-Methyluridine
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2'-Fluorothymidine (2'-Fluoro-2'-deoxythymidine) is a nucleoside analog and hCNT inhibitor, with an IC50 of 1.1 μM against hCNT1 and an IC50 of 9.7 μM against hCNT3. 2'-Fluorothymidine undergoes phosphorylation by cytosolic thymidine kinase (TK1) and mitochondrial thymidine kinase (TK2). 2'-Fluorothymidine acts as a backbone stabilizer in oligonucleotide synthesis and can also form radiolabeled candidates. 2'-Fluorothymidine is applicable in tumor-related research [1].
Cat. No.: HY-RS14556
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Research Areas:
TK1 Human Pre-designed siRNA Set A contains three designed siRNAs for TK1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23490
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Research Areas:
Tk1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Tk1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS17046
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Research Areas:
Tk1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Tk1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-128710R
CAS No.: 122799-38-6
Synonyms: 2'-Deoxy-2'-fluoro-5-Methyluridine (Standard)
Research Areas:
2'-Fluorothymidine (Standard) is the analytical standard of 2'-Fluorothymidine. This product is intended for research and analytical applications. 2'-Fluorothymidine (2'-Fluoro-2'-deoxythymidine) is a nucleoside analog and hCNT inhibitor, with an IC50 of 1.1 μM against hCNT1 and an IC50 of 9.7 μM against hCNT3. 2'-Fluorothymidine undergoes phosphorylation by cytosolic thymidine kinase (TK1) and mitochondrial thymidine kinase (TK2). 2'-Fluorothymidine acts as a backbone stabilizer in oligonucleotide synthesis and can also form radiolabeled candidates. 2'-Fluorothymidine is applicable in tumor-related research.
Cat. No.: HY-P82450A
Synonyms: EC 2.7.1.21; KITH; TK-1; TK1; Thymidine kinase 1; cytosolic
Cat. No.: HY-107025
CAS No.: 319425-66-6
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Research Areas:
Cf1743 is a potent anti-varicella-zoster virus (VZV) bicyclic nucleoside analogue. Cf1743 has antiviral activity, with an IC50 of 3.3 μM for VZV thymidine kinase (TK) .
Cat. No.: HY-P701043
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TK1; Epididymis Secretory Sperm Binding Protein; Thymidine Kinase 1; Thymidine Kinase 1, Soluble; Thymidine Kinase, Cytosolic; Thymidine Kinase; Cytosolic Thymidine Kinase
Cat. No.: HY-104083
CAS No.: 156126-12-4
Synonyms: N-MCT
Target:
North-methanocarbathymidine (N-MCT) is a potent antiviral agent. North-methanocarbathymidine inhibits DNA synthesis. North-methanocarbathymidine demonstrates potent antiviral activity against HSV-1, HSV-2 and KSHV. North-methanocarbathymidine exhibits anticancer activity against colon adenocarcinoma expressing HSV-tk .
Cat. No.: HY-W770090
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
