55612-21-0

2'-Deoxy-2'-fluoro-5-iodouridine Chemical Structure
55612-21-0

Chemical Structure

2'-Deoxy-2'-fluoro-5-iodouridine

Synonym(s): FIRU

  • CAS No.: 55612-21-0
  • Formula:C9H10FIN2O5
  • Molecular Weight:372.09

IUPAC Name: methyl 2-(1H-tetrazol-1-yl)acetate

InChIKey: IPVFGAYTKQKGBM-UAKXSSHOSA-N

SMILES: O[C@H]1[C@@H](F)[C@H](N2C(NC(C(I)=C2)=O)=O)O[C@@H]1CO

Biological Activity: 2'-Deoxy-2'-fluoro-5-iodouridine (FIRU) is a nucleoside analog. When labeled with 123I, 2'-Deoxy-2'-fluoro-5-iodouridine accumulates highly selectively in tumors expressing the HSV1-tk gene. Radiolabeled 2'-Deoxy-2'-fluoro-5-iodouridine enables imaging of adenovirus-mediated HSV1-tk suicide gene transfer[1].

Cat. No. Product Name Purity Description Pricing
HY-W342664 		2'-Deoxy-2'-fluoro-5-iodouridine 99.46% 2'-Deoxy-2'-fluoro-5-iodouridine (FIRU) is a nucleoside analog. When labeled with 123I, 2'-Deoxy-2'-fluoro-5-iodouridine accumulates highly selectively in tumors expressing the HSV1-tk gene. Radiolabeled 2'-Deoxy-2'-fluoro-5-iodouridine enables imaging of adenovirus-mediated HSV1-tk suicide gene transfer.
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