77 Results for "

Tachykinin

" in MedChemExpress (MCE) Product Catalog:
Products (77)

77 Results for "Tachykinin" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-P0197
CAS No.: 86933-74-6
Synonyms: Substance K; Neurokinin α; Neuromedin L; NKA
Target:  

Neurokinin Receptor

Research Areas:  

Neurological Disease Endocrinology

Neurokinin A (Substance K), a peptide neurotransmitter of the tachykinin family, acts via the NK-2 receptor. Neurokinin A acts as a major mediator in human airway and gastrointestinal tissues .
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-P0197A
CAS No.: 2828433-19-6
Synonyms: Substance K TFA; Neurokinin α TFA; Neuromedin L TFA; NKA TFA
Target:  

Neurokinin Receptor

Research Areas:  

Neurological Disease Endocrinology

Neurokinin A TFA (Substance K TFA), a peptide neurotransmitter of the tachykinin family, acts via the NK-2 receptor. Neurokinin A acts as a major mediator in human airway and gastrointestinal tissues .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-14406A
CAS No.: 148687-76-7
Purity:  99.30%
Target:  

Neurokinin Receptor

Research Areas:  

Neurological Disease Cancer

L-733060 hydrochloride is a selective neurokinin-1 (NK-1) receptor antagonist. L-733060 hydrochloride mainly regulates pain transmission and neural plasticity by blocking the binding of Substance P (P substance) to the NK-1 receptor. L-733060 hydrochloride blocks the promoting effect of Substance P on long-term potentiation (LTP) in the hippocampus. L-733060 hydrochloride reverses the orofacial hyperalgesia induced by experimental occlusal interference (EOI) in rats. L-733060 hydrochloride hydrochloride inhibits neurogenic plasma extravasation at a dose that does not cause adverse cardiovascular effects in rodents, and also acts as an anti-tumor agent. L-733060 hydrochloride can be used for the study of chronic orofacial pain .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-151413
CAS No.: 126050-12-2
Purity:  99.69%
Target:  

Neurokinin Receptor

Research Areas:  

Neurological Disease

MEN 10207 is a selective NK-2 tachykinin receptor (Neurokinin Receptor) antagonist. MEN 10207 has pA2 values of 5.2, 7.9 and 4.9 in three monoreceptor in vitro assays for NK-1, NK-2 and NK-3 tachykinin receptors, respectively.
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-P1276A
Synonyms: Neurokinin-2 receptor antagonist TFA
Target:  

Neurokinin Receptor

Research Areas:  

Endocrinology

Men 10376 TFA is a selective tachykinin NK-2 receptor antagonist, with a Ki of 4.4 μM for rat small intestine NK-2 receptor .
loading...
    loading...
Cat. No.: HY-P0242
CAS No.: 86933-75-7
Neurokinin B is a tachykinin family peptide that preferentially binds to and activates NK3R over other tachykinin receptors. Neurokinin B preferentially binds to the substance P receptor (SP-N receptor) and mediates acetylcholine release from cholinergic neurons. Neurokinin B regulates the pulsatile release of Kisspeptin and GnRH, stimulates or inhibits the secretion of luteinizing hormone (HY-P2293), regulates reproductive function via metabolic signals, and drives the onset of puberty. Neurokinin B exerts vasoactive effects and induces contraction of isolated guinea pig ileum. Neurokinin B can be used in studies related to hypogonadotropic hypogonadism .
loading...
    loading...
Cat. No.: HY-P0242A
CAS No.: 101536-55-4
Neurokinin B TFA is a tachykinin family peptide that preferentially binds to and activates NK3R over other tachykinin receptors. Neurokinin B TFA preferentially binds to the substance P receptor (SP-N receptor) and mediates acetylcholine release from cholinergic neurons. Neurokinin B TFA regulates the pulsatile release of Kisspeptin and GnRH, stimulates or inhibits the secretion of luteinizing hormone (HY-P2293), regulates reproductive function via metabolic signals, and drives the onset of puberty. Neurokinin B TFA exerts vasoactive effects and induces contraction of isolated guinea pig ileum. Neurokinin B TFA can be used in studies related to hypogonadotropic hypogonadism .
loading...
    loading...
Cat. No.: HY-W010922
CAS No.: 162558-25-0
Research Areas:  

Others

Fmoc-Dap (Boc)-OH is an amino acid derivative bearing the Fmoc protecting group. Fmoc-Dap (Boc)-OH supports Fmoc-based solid-phase peptide synthesis for the preparation of bicyclic tachykinin NK2 receptor antagonists .
loading...
    loading...
Cat. No.: HY-P1192
CAS No.: 133156-06-6
Target:  

Neurokinin Receptor

Research Areas:  

Neurological Disease

GR-73632 is a tachykinin NK1 receptor agonist. GR-73632 activates spinal NK1 receptors to induce scratching, biting and licking behaviors. GR-73632 activates peripheral NK1 receptors to trigger lacrimation in guinea pigs, and activates central NK1 receptors to induce repetitive hind paw tapping behavior in gerbils. GR-73632 is applicable to research related to pruritus .
loading...
    loading...
Cat. No.: HY-108482
CAS No.: 132746-60-2
CP-96,345 is a specific, highly potent, and orally active tachykinin and substance P receptor non-peptide inhibitor. CP-96,345 prevents the drop in blood pressure evoked by substance P and neurokinin A. CP-96,345 can be used for researching neurogenic inflammation .
loading...
    loading...
Cat. No.: HY-107691
CAS No.: 158848-32-9
Purity:  ≥99.0%
GR 159897 is a highly potent, selective, competitive, brain-penetrated non-peptide neurokinin 2 (NK2) receptor antagonist. GR 159897 has little or no affinity for NK1 and NK3 receptors. GR 159897 inhibits binding of [ 3H]GR100679 to human NK2 (hNK2)-CHO cells and rat colon membranes with pKis of 9.51 and 10, respectively. Antagonizes bronchoconstriction. Anxiolytic-like and anti-tumor effects .
loading...
    loading...
Cat. No.: HY-P1012
CAS No.: 110880-55-2
Target:  

Neurokinin Receptor

Research Areas:  

Neurological Disease Endocrinology

[Sar9,Met(O2)11]-Substance P is a tachykinin NK1 receptor selective agonist.
loading...
    loading...
Cat. No.: HY-P1186
CAS No.: 2990-43-4
Synonyms: Eledoisin-Related Peptide; Eledoisin RP
Target:  

Neurokinin Receptor

Research Areas:  

Neurological Disease

Eledoisin Related Peptide is a Substance P analog that excites neurons and triggers behavioral responses. Eledoisin Related Peptide is also a tachykinin receptor ligand.
loading...
    loading...
Cat. No.: HY-P3092
CAS No.: 26145-48-2
Target:  

Neurokinin Receptor

Research Areas:  

Neurological Disease

Phyllomedusin, an tachykinin decapeptide, is a NK1 receptor agonist. Phyllomedusin has vasodilating activity and provokes the contraction of the pylorus .
loading...
    loading...
Cat. No.: HY-P1183
CAS No.: 126985-97-5
Target:  

Peptides

Research Areas:  

Neurological Disease Endocrinology

Locustatachykinin I is a insect tachykinin-related peptide isolated from Locusta migratoria. Locustatachykinin I exhibits sequence homologies with the vertebrate tachykinins. In Lacanobia, Locustatachykinin I is also a substrate for a deamidase .
loading...
    loading...
Cat. No.: HY-P0236A
Target:  

Neurokinin Receptor

Research Areas:  

Neurological Disease Endocrinology

Neurokinin A (4-10) TFA is a tachykinin NK2 receptor agonist .
loading...
    loading...
Cat. No.: HY-P11312
CAS No.: 2770688-17-8
Target:  

Neurokinin Receptor

Research Areas:  

Neurological Disease

[S5K, F6Y, L9mL, M10Mox] neurokinin A (4-10) is a neuropeptide A analog and a peptide fragment of EB1002 (HY-P10746). [S5K, F6Y, L9mL, M10Mox] neurokinin A (4-10) is highly selective for mouse tachykinin receptors and human tachykinin receptor NK1R .
loading...
    loading...
Cat. No.: HY-108479
CAS No.: 153050-21-6
Synonyms: SR140333
Target:  

Neurokinin Receptor

Research Areas:  

Neurological Disease

Nolpitantium (SR140333) is a potent, selective, competitive, non-peptide tachykinin NK1 receptor antagonist. Nolpitantium blocks the activation of rat thalamic neurons after nociceptive stimulation .
loading...
    loading...
Cat. No.: HY-P3890A
Target:  

Neurokinin Receptor

Research Areas:  

Neurological Disease

Substance P (5-11) TFA TFA, the C-terminal heptapeptide of Substance P (HY-P0201), is a neuropeptide. Substance P (5-11) TFA TFA binds to NK-1 tachykinin receptor .
loading...
    loading...
Cat. No.: HY-P3799
CAS No.: 61123-13-5
Target:  

Neurokinin Receptor

Research Areas:  

Neurological Disease

[Glp6] Substance P (6-11) is an analogue of substance P (6-11). Substance P (6-11) stimulates [3H]-inositol monophosphate ([3H]-IP1) formation in rat urinary bladder by acting on the 'septide-sensitive' tachykinin receptors .
loading...
    loading...