24 Results for "

Thiazolyl

" in MedChemExpress (MCE) Product Catalog:
Products (24)

24 Results for "Thiazolyl" in MCE Product Catalog:

186
Thiazolyl Blue
Thiazolyl Blue
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186 Publications Verification
Cat. No.: HY-15924
CAS No.: 298-93-1
Synonyms: MTT; Thiazolyl Blue Tetrazolium bromide; MethylThiazolyldiphenyl-tetrazolium bromide
Thiazolyl Blue (MTT) is a cell-permeable and positively charged tetrazolium dye that is used to detect reductive metabolism in cells. Thiazolyl Blue is taken up by cells through the plasma membrane and then reduced to formazan by intracellular NAD (P) H-oxidoreductases. Thiazolyl Blue is frequently used in colorimetric assays to measure cell proliferation, cytotoxicity, and apoptosis .
13
Icatibant acetate
Icatibant acetate
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13 Cited Publications
Cat. No.: HY-108896
CAS No.: 138614-30-9
Purity:  99.85%
Synonyms: HOE 140 acetate
Target:  

Bradykinin Receptor

Research Areas:  

Inflammation/Immunology

Icatibant acetate (HOE-140 acetate) is a potent and specific peptide antagonist of bradykinin B2 receptor with an IC50 and Ki of 1.07 nM and 0.798 nM respectively .
4
Thiabendazole
Thiabendazole
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4 Cited Publications
Cat. No.: HY-B0263
CAS No.: 148-79-8
Synonyms: Tiabendazole; 2-(4-Thiazolyl)benzimidazole
Target:  

Environmental Pollutants Mitochondrial Metabolism Parasite Caspase VEGFR MDM-2/p53 CDK Interleukin Related

Research Areas:  

Infection Cardiovascular Disease Inflammation/Immunology Cancer

Thiabendazole is an orally available benzimidazole fungicide with repellent and anticancer activities. Thiabendazole can result in developmental malformations. Thiabendazole can be used for modeling .
1
ICA
ICA
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1 Cited Publications
Cat. No.: HY-22044
CAS No.: 3374-88-7
Synonyms: N-[4-(2-Pyridinyl)-2-Thiazolyl]-2-pyridinamine
Target:  

Parasite

Research Areas:  

Infection Cardiovascular Disease

ICA (N-(pyridin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine) is a SK channel inhibitor that has antileishmanial activity with an IC50 of 2.1 µM.
Isobutylamido thiazolyl resorcinol
Isobutylamido thiazolyl resorcinol
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Cat. No.: HY-W251181
CAS No.: 1428450-95-6
Target:  

Tyrosinase

Research Areas:  

Metabolic Disease

Isobutylamido thiazolyl resorcinol is a selective hTyr inhibitor with an IC50 of 1.1  μM. Isobutylamido thiazolyl resorcinol shows an IC50 of 108  μM against mushroom Tyrosinase. Isobutylamido thiazolyl resorcinol effectively prevents pigmentation caused by UVB irradiation. Isobutylamido thiazolyl resorcinol significantly improves the visibility of acne-induced hyperpigmentation .
Thiabendazole-d4
Thiabendazole-d4
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Cat. No.: HY-B0263S
CAS No.: 1190007-20-5
Synonyms: 2-(4-Thiazolyl)benzimidazole-d4
Thiabendazole-d4 is a deuterated form of Thiabendazole, which is an antiseptic, antifungal and antiparasitic agent .
Thiabendazole-13C6
Thiabendazole-13C6
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Cat. No.: HY-B0263S1
CAS No.: 2140327-29-1
Synonyms: 2-(4-Thiazolyl)benzimidazole-13C6
Thiabendazole- 13C6 is the 13C6 labeled Thiabendazole. Thiabendazole inhibites the mitochondrial helminth-specific enzyme, fumarate reductase, with anthelminthic property.
2-Acetylthiazole
2-Acetylthiazole
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Cat. No.: HY-Y0045
CAS No.: 24295-03-2
Synonyms: 1-(1,3-Thiazol-2-yl)ethanone; 1-(Thiazol-2-yl)ethanone; Methyl 2-Thiazolyl ketone
2-Acetylthiazole (1-(1,3-Thiazol-2-yl)ethanone; 1-(Thiazol-2-yl)ethanone; Methyl 2-thiazolyl ketone) is a flavor compound. 2-Acetylthiazole is a kind of biological materials or organic compounds that are widely used in life science research .
4-(2-Methyl-4-thiazolyl)phenol
4-(2-Methyl-4-thiazolyl)phenol
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Cat. No.: HY-D0126
CAS No.: 30686-73-8
Synonyms: 4-(2-Methylthiazol-4-yl)phenol
4-(2-Methylthiazol-4-yl)phenol is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Thiazoplanomicin
Thiazoplanomicin
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Cat. No.: HY-P11027
Target:  

Bacterial Antibiotic

Research Areas:  

Infection

Thiazoplanomicin (Compound 1) is a thiazolyl peptide antibiotic. Thiazoplanomicin can be isolated from the leaf-litter actinomycete Actinoplanes sp. MM794L-181F6. Thiazoplanomicin has potent antimicrobial activities against gonococcal strains (especially drug-resistant strains) and Gram-positive bacterium with MICs of 31.2-125 and 0.5-15.6 ng/mL, respectively. Thiazoplanomicin has no antibacterial activity against E.coli. Thiazoplanomicin can be used for bacterial infections research .
GE 2270A
GE 2270A
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Cat. No.: HY-106882
CAS No.: 134861-34-0
Synonyms: MDL 62879
Target:  

Bacterial Antibiotic

Research Areas:  

Infection

GE 2270A (MDL 62879) is an antibiotic. GE 2270A inhibits gram-positive bacteria and anaerobes by inhibiting protein synthesis. GE 2270A can be used for the research of infection .
Fmoc-L-(4-thiazolyl)-Alanine
Fmoc-L-(4-thiazolyl)-Alanine
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Cat. No.: HY-W010997
CAS No.: 205528-32-1
Target:  

Amino Acid Derivatives

Research Areas:  

Others

Fmoc-L-(4-thiazolyl)-Alanine is an alanine derivative .
2-Acetylthiazole-13C2
2-Acetylthiazole-13C2
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Cat. No.: HY-Y0045S
CAS No.: 3028870-64-3
Synonyms: 1-(1,3-Thiazol-2-yl)ethanone-13C2; 1-(Thiazol-2-yl)ethanone-13C2; Methyl 2-Thiazolyl ketone-13C2
2-Acetylthiazole (1-(1,3-Thiazol-2-yl)ethanone; 1-(Thiazol-2-yl)ethanone; Methyl 2-thiazolyl ketone)- 13C2 is 13C labeled 2-Acetylthiazole (HY-Y0045). 2-Acetylthiazole is a Cramer Class II fragrance ingredient. 2-Acetylthiazole does not induce genotoxic effects, does not induce skin sensitization and does not induce phototoxic or photoallergenic effects .
Nek2/Hec1-IN-1
Nek2/Hec1-IN-1
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Cat. No.: HY-136747
CAS No.: 560103-80-2
Synonyms: Nec2/Hec1 inhibitor
Target:  

Drug Derivative

Research Areas:  

Cancer

N-[4-(2,4-Dimethylphenyl)-2-thiazolyl]-4-pyridinecarboxamide is a derivative of INH1 with anticancer activity. It is cytotoxic to MDA-MB-231, MDA-MB-488, HeLa, and K562 cells (IC50s=1.1, 3.4, 1.6, and 1.2 μM, respectively).
PD-134672
PD-134672
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Cat. No.: HY-19145
CAS No.: 135704-06-2
Synonyms: CI-992
Target:  

Renin

Research Areas:  

Cancer

PD-134672 (CI-992) is a renin inhibitor containing a 2-amino-4-thiazolyl substituent. PD-134672 potently inhibits monkey renin in vitro and only weakly inhibits the related aspartic protease bovine feline hepsin D. The compound exhibits oral hypotensive activity in hyperreninemic normotensive monkeys. Based on its superior efficacy and long-lasting effects in vitro and in the normotensive macaque model, PD-134672 was selected for further evaluation in renal hypertensive monkeys.
Catenulopyrizomicin A
Catenulopyrizomicin A
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Cat. No.: HY-N12483
Category:  

Alkaloids Microorganisms Pyridine Alkaloids

Target:  

HBV

Catenulopyrizomicin A has a thiazolyl pyridine moiety. Catenulopyrizomicin A can be isolated from the fermentation broth of rare actinomycete Catenuloplanes sp. Catenulopyrizomicin A has anti-Hepatitis B virus activity .
Tyrosinase-IN-12
Tyrosinase-IN-12
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Cat. No.: HY-149404
CAS No.: 1860779-42-5
Purity:  99.83%
Target:  

Reactive Oxygen Species (ROS) Tyrosinase

Research Areas:  

Others

Non-competitive tyrosinase inhibitor (Tyrosinase-IN-12) is a potent, non-competitive tyrosinase inhibitor with an IC50 value of 49.33 ± 2.64 µM and Ki value of 31.25 ± 0.25 µM. Non-competitive tyrosinase inhibitor (Tyrosinase-IN-12) have the highest radical scavenging activity to reduce the production of reactive oxygen species (ROS) with an IC50 value of 25.39 ± 0.77 µM. Non-competitive tyrosinase inhibitor (Tyrosinase-IN-12) can be used for anti-browning substances in the food and agricultural sectors .
Thiabendazole (Standard)
Thiabendazole (Standard)
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Cat. No.: HY-B0263R
CAS No.: 148-79-8
Synonyms: Tiabendazole (Standard); 2-(4-Thiazolyl)benzimidazole (Standard)
Target:  

Reference Standards Mitochondrial Metabolism Parasite

Research Areas:  

Infection

Thiabendazole (Standard) is the analytical standard of Thiabendazole. This product is intended for research and analytical applications. Thiabendazole inhibits worm-specific fumarate reductase and has anthelmintic properties.
EGFR-TK-IN-5
EGFR-TK-IN-5
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Cat. No.: HY-172156
Target:  

EGFR

Research Areas:  

Cancer

EGFR-TK-IN-5 (Compound NCE 2) is a thiazolyl-pyrazoline derivative. EGFR-TK-IN-5 exhibits strong inhibitory activity and stability against EGFR. EGFR-TK-IN-5 can be used in the study of cancer .
Kocurin
Kocurin
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Cat. No.: HY-W748000
CAS No.: 1374772-61-8
Synonyms: PM181104; Baringolin
Category:  

Microorganisms

Target:  

Antibiotic Bacterial

Kocurin (PM181104) is a thiazolyl cyclic-peptide antibiotic. Kocurin inhibits bacterial growth by impeding bacterial protein biosynthesis during the translation phase. Kocurin has strong inhibitory activity against Gram-positive bacteria, but no activity against fungi and Gram-negative bacteria .
Assay Types