148-79-8
148-79-8
Chemical Structure
Thiabendazole
Synonym(s): Tiabendazole; 2-(4-Thiazolyl)benzimidazole
- CAS No.: 148-79-8
- Formula:C10H7N3S
- Molecular Weight:201.25
IUPAC Name: 4-(1H-benzo[d]imidazol-2-yl)thiazole
InChIKey: WJCNZQLZVWNLKY-UHFFFAOYSA-N
SMILES: C1(C2=CSC=N2)=NC3=CC=CC=C3N1
Biological Activity: Thiabendazole is an orally available benzimidazole fungicide with repellent and anticancer activities. Thiabendazole can result in developmental malformations. Thiabendazole can be used for modeling[1][2][3][4][5].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Thiabendazole | 99.94% | Thiabendazole is an orally available benzimidazole fungicide with repellent and anticancer activities. Thiabendazole can result in developmental malformations. Thiabendazole can be used for modeling. | ||||||||||||||||||||
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Thiabendazole (Standard) | 99.96% | Thiabendazole (Standard) is the analytical standard of Thiabendazole. This product is intended for research and analytical applications. Thiabendazole inhibits worm-specific fumarate reductase and has anthelmintic properties. | ||||||||||||||||||||
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Thiabendazole-13C6 | 99.8% | Thiabendazole-13C6 is the 13C6 labeled Thiabendazole. Thiabendazole inhibites the mitochondrial helminth-specific enzyme, fumarate reductase, with anthelminthic property. | ||||||||||||||||||||
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Thiabendazole-d6 | Thiabendazole-d6 is a deuterated labeled Thiabendazole (HY-B0263). Thiabendazole is an orally available benzimidazole fungicide with repellent and anticancer activities. Thiabendazole can result in developmental malformations. Thiabendazole can be used for modeling. | |||||||||||||||||||||
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Thiabendazole-d4 | 98.84% | Thiabendazole-d4 is a deuterated form of Thiabendazole, which is an antiseptic, antifungal and antiparasitic agent. | ||||||||||||||||||||
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Harmane-d4 | Harmane-d4 is deuterium-labeled Harmane (HY-101392). | |||||||||||||||||||||
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2-(3-Pyridyl)-benzimidazole | 2-(3-Pyridyl)-benzimidazole is an Aminopyrine N-Demethylase inhibitor. | |||||||||||||||||||||
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5-Hydroxythiabendazole | 99.16% | 5-Hydroxythiabendazole (5-OHTBZ) is a biomarker of Thiabendazole (HY-B0263) exposure. | ||||||||||||||||||||
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5-Hydroxythiabendazole (Standard) | ≥98% | 5-Hydroxythiabendazole (Standard) is the analytical standard of 5-Hydroxythiabendazole. This product is intended for research and analytical applications. 5-Hydroxythiabendazole (5-OHTBZ) is a biomarker of Thiabendazole (HY-B0263) exposure. | ||||||||||||||||||||
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Carbendazim-d4 | 99.65% | Carbendazim-d4 is the deuterium labeled Carbendazim. Carbendazim is a potent and orally active broad-spectrum?benzimidazole fungicide and can be acts as a pesticide for fungal diseases research, such as Seproria,?Fusarium?and?Sclerotina. Carbendazim is a benzimidazole (HY-Y1825) derivative with antitumor activity and used for cancer research, especially advanced solid tumors and lymphoma. | ||||||||||||||||||||
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2-Benzimidazolemethanol | ≥98.0% | 2-Benzimidazolemethanol (1H-Benzimidazol-2-ylmethanol) is a chiral ligand. | ||||||||||||||||||||
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2-Mercaptobenzimidazole-d4 | 2-Mercaptobenzimidazole-d4 is the deuterium labeled 2-Benzimidazolethiol. | |||||||||||||||||||||
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Fuberidazole | 99.90% | Fuberidazole (BAY 33172; Furidazole) is a fungicide. Fuberidazole shows a synergistic effect with cucurbituril (CB) macromolecules, such as CB7 and CB8. Studies have shown that, CB8 induces pKa shifts on Fuberidazole. Fuberidazole significantly inhibits the growth of B. cinerea. | ||||||||||||||||||||
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2-Quinoxalinecarboxylic acid-d4 | 98.40% | 2-Quinoxalinecarboxylic acid-d4 is the deuterium labeled 2-Quinoxalinecarboxylic acid. | ||||||||||||||||||||
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2-(2′-Pyridyl)benzimidazole | 99.88% | 2-(2’-Pyridyl)benzimidazole is a potentially tridentate ligand that can form stable complexes with various transition metal ions. 2-(2’-Pyridyl)benzimidazole can be used as an anti-inflammatory agent and an inhibitor of Escherichia coli methionine aminopeptidase. | ||||||||||||||||||||
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Quinoxaline-d4 | Quinoxaline-d4 is the deuterium labeled Quinoxaline. Quinoxaline is a chemical compound that acts as an intermediate for anti-tuberculosis agent Pyrazinamide. Quinoxaline presents a structure that is similar to quinolone antibiotics. | |||||||||||||||||||||
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2-(4-Pyridyl)benzimidazole | 2-Pyridin-4-yl-1H-benzimidazole (2-(pyridin-4-yl)-1H-benzimidazole) is a metal-organic framework (MOF). | |||||||||||||||||||||
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NP-184 | NP-184 is a novel orally active antithrombotic agent. NP-184 selectively inhibits TXA2 synthase activity with an IC50 value of 4.3 μM. NP-184 has antiplatelet and antithrombotic activities. NP-184 can be used in the research of thromboembolic diseases. | |||||||||||||||||||||
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2-(1H-Imidazol-2-yl)-3H-imidazo[4,5-c]pyridine | 2-(1H-Imidazol-2-yl)-3H-imidazo[4,5-c]pyridine is a metal-organic framework (MOF). | |||||||||||||||||||||
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1H-Benzotriazole-4,5,6,7-d4 | 99.9% | 1H-Benzotriazole-4,5,6,7-d4 is the deuterium labeled 1H-Benzo[d][1,2,3]triazole. | ||||||||||||||||||||
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References
- [1]. Budetić M, et al. Review of Characteristics and Analytical Methods for Determination of Thiabendazole. Molecules. 2023 May 6;28(9):3926. [Content Brief]
- [2]. Zhang, J., et al., Thiabendazole, a well-known antifungal drug, exhibits anti-metastatic melanoma B16F10 activity via inhibiting VEGF expression and inducing apoptosis. Pharmazie, 2013. 68(12): p. 962-8. [Content Brief]
- [3]. Cha, H.J., et al., Evolutionarily repurposed networks reveal the well-known antifungal drug thiabendazole to be a novel vascular disrupting agent. PLoS Biol, 2012. 10(8): p. e1001379. [Content Brief]
- [4]. Park J, et al. Developmental defects induced by thiabendazole are mediated via apoptosis, oxidative stress and alteration in PI3K/Akt and MAPK pathways in zebrafish. Environ Int. 2023 Jun;176:107973. [Content Brief]
- [5]. Elgebaly SA, et al. Thiabendazole-induced suppression of renal damage in a murine model of autoimmune disease. Am J Pathol. 1984 May;115(2):204-11. [Content Brief]
