560103-80-2
560103-80-2
Chemical Structure
Nek2/Hec1-IN-1
Synonym(s): Nec2/Hec1 inhibitor
- CAS No.: 560103-80-2
- Formula:C17H15N3OS
- Molecular Weight:309.39
IUPAC Name: N-(4-(2,4-dimethylphenyl)thiazol-2-yl)isonicotinamide
InChIKey: IBQLKKBLBXJSGU-UHFFFAOYSA-N
SMILES: O=C(C1=CC=NC=C1)NC2=NC(C3=CC=C(C)C=C3C)=CS2
Biological Activity: N-[4-(2,4-Dimethylphenyl)-2-thiazolyl]-4-pyridinecarboxamide is a derivative of INH1 with anticancer activity. It is cytotoxic to MDA-MB-231, MDA-MB-488, HeLa, and K562 cells (IC50s=1.1, 3.4, 1.6, and 1.2 μM, respectively).
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Nek2/Hec1-IN-1 | N-[4-(2,4-Dimethylphenyl)-2-thiazolyl]-4-pyridinecarboxamide is a derivative of INH1 with anticancer activity. It is cytotoxic to MDA-MB-231, MDA-MB-488, HeLa, and K562 cells (IC50s=1.1, 3.4, 1.6, and 1.2 μM, respectively). | |||||||||||||||||||||
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