959 Results for "

anticancer mechanism

" in MedChemExpress (MCE) Product Catalog:
Products (959)

959 Results for "anticancer mechanism" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-N2389
CAS No.: 50773-42-7
Formosanin C is a diosgenin saponin with multiple biological activities. Formosanin C possesses multiple anti-tumor mechanisms, including inducing apoptosis and autophagy, blocking the cell cycle, inhibiting metastasis and inducing ferroptosis. Formosanin C can inhibit the NF-κB signaling pathway to exert anti-inflammatory effects, and enhance the activity of immune cells. Formosanin C exhibits the inhibiting effect against C. albicans. Formosanin C can be used for the study of anti-inflammation, antifungal anti and anti-cancer (including lung cancer, liver cancer, breast cancer and colorectal cancer, etc.) .
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4
4 Cited Publications
Cat. No.: HY-19896
CAS No.: 1039455-84-9
Target:  

MDM-2/p53 Apoptosis

Research Areas:  

Cancer

COTI-2, an anti-cancer agent with low toxicity, is an orally available third generation activator of p53 mutant forms. COTI-2 acts both by reactivating mutant p53 and inhibiting the PI3K/AKT/mTOR pathway. COTI-2 induces apoptosis in multiple human tumor cell lines. COTI-2 exhibits antitumor activity in HNSCC through p53-dependent and -independent mechanisms. COTI-2 converts mutant p53 to wild-type conformation .
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2
2 Cited Publications
Cat. No.: HY-W009163
CAS No.: 957-75-5
Research Areas:  

Cancer

5-Bromouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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2
2 Cited Publications
Cat. No.: HY-13755A
CAS No.: 142825-10-3
Purity:  99.48%
Synonyms: L-Sulforaphane
(R)-Sulforaphane (L-Sulforaphane) is a orally active, potent inducer of the Keap1/Nrf2/ARE pathway, exhibiting antioxidant and anticancer activities. (R)-Sulforaphane primarily functions by upregulating phase II detoxifying enzymes in cells, aiding in the removal of carcinogens and combating oxidative stress. (R)-Sulforaphane is capable of modulating gene expression, influencing various signaling pathways, including Nrf2, NF-κB, and AP-1. (R)-Sulforaphane can be used in studies of tumor biology, antioxidant defense mechanisms, as well as inflammation and immune responses .
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1
1 Cited Publications
Cat. No.: HY-N0585
CAS No.: 5442-12-6
Synonyms: (Rac)-NCTD
(Rac)-Norcantharidin ((Rac)-NCTD) is the racemic form of Norcantharidin. Norcantharidin is a demethylated derivative of Cantharidin (HY-N0209) and has antitumor activity .
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1
1 Cited Publications
Cat. No.: HY-131795
CAS No.: 4105-39-9
Purity:  98.82%
Research Areas:  

Cancer

2-Methylthioadenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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1
1 Cited Publications
Cat. No.: HY-152710
CAS No.: 20299-15-4
Research Areas:  

Others

5-Methoxycarbonylmethyl-2-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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1
1 Cited Publications
Cat. No.: HY-154147
CAS No.: 5132-79-6
Purity:  99.56%
Research Areas:  

Cancer

2’-Deoxy-N1-methylguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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1
1 Cited Publications
Cat. No.: HY-152693
CAS No.: 13048-95-8
Research Areas:  

Others

N4-Methyl-2’-O-methyl-cytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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1
1 Cited Publications
Cat. No.: HY-126833A
CAS No.: 187100-75-0
Purity:  95.50%
Myristoyl coenzyme A lithium is lithium-labeled myristoylated coenzyme A (CoA). Myristoylation is an essential process in viruses and is generally controlled by N-myristoyltransferase (NMT). And NMT is more active in colon epithelial tumors than in normal cells. Reduced Ccoenzyme A (CoA) is known to be a key regulator of NMT activity, whereas oxidized CoA does not allow NMT to promote myristoylation. Myristoyl coenzyme A blocks the demyristoylation process and has potential anticancer and antiviral mechanisms .
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1
1 Cited Publications
Cat. No.: HY-126833B
CAS No.: 799812-85-4
Synonyms: 14:0 Coenzyme A triammonium; S-Tetradecanoate-CoA triammonium; S-Tetradecanoate-coenzyme A triammonium
Target:  

Endogenous Metabolite

Research Areas:  

Infection Cancer

Myristoyl coenzyme A triammonium (14:0 Coenzyme A) is a myristoylated coenzyme A (CoA). Myristoylation is an essential process in viruses and is generally controlled by N-myristoyltransferase (NMT). And NMT is more active in colon epithelial tumors than in normal cells. Reduced Ccoenzyme A (CoA) is known to be a key regulator of NMT activity, whereas oxidized CoA does not allow NMT to promote myristoylation. Myristoyl coenzyme A blocks the demyristoylation process and has potential anticancer and antiviral mechanisms .
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Cat. No.: HY-P5285
CAS No.: 496823-34-8
Target:  

Parasite

Lunasin is a bioactive peptide with antioxidant, anti-inflammatory, anticancer and anti-aging properties. Lunasin can be isolated from soybean. Lunasin also has an epigenetic mechanism of action associated with histone acetylation. Lunasin can be internalized into cells and inhibit Oncosphere formation in cancer cells .
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Cat. No.: HY-112581
CAS No.: 35542-01-9
Purity:  99.98%
Research Areas:  

Cancer

5-Methoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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Cat. No.: HY-W587829
CAS No.: 7236-57-9
Research Areas:  

Cancer

4-Thiothymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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Cat. No.: HY-130805
CAS No.: 957-77-7
Purity:  98.94%
Synonyms: OHUrd
Research Areas:  

Others Cancer

5-Hydroxyuridine (OHUrd) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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Cat. No.: HY-W154568
CAS No.: 14675-48-0
Synonyms: 6-MPR
Research Areas:  

Others Cancer

6-Methylpurine riboside is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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Cat. No.: HY-W129233
CAS No.: 131175-87-6
Synonyms: Dihydroartemisinin (α,β mixture)
Research Areas:  

Infection Cancer

Dihydroartemisinin (mixture of α and β isomers) is an anti-malaria and anticancer agent, as well as an active metabolite of artemisinin and its derivatives. Dihydroartemisinin exerts anticancer effects through various molecular mechanisms, such as inhibiting proliferation, inducing apoptosis, inhibiting tumor metastasis and angiogenesis, promoting immune function, inducing autophagy and endoplasmic reticulum stress .
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Cat. No.: HY-151414
CAS No.: 13146-72-0
Purity:  99.84%
Research Areas:  

Cancer

3'-Deoxyinosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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Cat. No.: HY-154534
CAS No.: 5682-25-7
Purity:  99.91%
Research Areas:  

Cancer

Alpha-Adenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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Cat. No.: HY-130806
CAS No.: 5626-99-3
Purity:  98.71%
Synonyms: H2dUrd
Research Areas:  

Cancer

Dihydrodeoxyuridine (H2dUrd) is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
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