5-Methoxycarbonylmethyl-2-thiouridine

Cat. No.: HY-152710 Purity: 99.52%: Data Sheet
COA

SDS
Handling Instructions
FAQs
Technical Support

5-Methoxycarbonylmethyl-2-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.

For research use only. We do not sell to patients.

5-Methoxycarbonylmethyl-2-thiouridine Chemical Structure

CAS No. : 20299-15-4

Size	Stock	Quantity
1 mg	In-stock	Estimated Time of Arrival: December 31
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

1 Publications Citing Use of MCE 5-Methoxycarbonylmethyl-2-thiouridine

•Cell. 2025 Oct 30;188(22):6151-6169.e24. [Abstract]

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Biological Activity
Purity & Documentation
References
Customer Review

Description

Molecular Weight

332.33

Formula

C₁₂H₁₆N₂O₇S

CAS No.

20299-15-4

Appearance

Solid

Color

White to off-white

SMILES

OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N(C=C2CC(OC)=O)C(NC2=O)=S)O1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (300.91 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	3.0091 mL	15.0453 mL	30.0906 mL
5 mM	0.6018 mL	3.0091 mL	6.0181 mL
10 mM	0.3009 mL	1.5045 mL	3.0091 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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In Vivo Dissolution Calculator

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.52%

Select Batch:

Data Sheet (274 KB) SDS (254 KB)

COA (249 KB) HNMR (259 KB) RP-HPLC (277 KB) MS (71 KB)

Handling Instructions (2659 KB)

References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	3.0091 mL	15.0453 mL	30.0906 mL	75.2264 mL
	5 mM	0.6018 mL	3.0091 mL	6.0181 mL	15.0453 mL
	10 mM	0.3009 mL	1.5045 mL	3.0091 mL	7.5226 mL
	15 mM	0.2006 mL	1.0030 mL	2.0060 mL	5.0151 mL
	20 mM	0.1505 mL	0.7523 mL	1.5045 mL	3.7613 mL
	25 mM	0.1204 mL	0.6018 mL	1.2036 mL	3.0091 mL
	30 mM	0.1003 mL	0.5015 mL	1.0030 mL	2.5075 mL
	40 mM	0.0752 mL	0.3761 mL	0.7523 mL	1.8807 mL
	50 mM	0.0602 mL	0.3009 mL	0.6018 mL	1.5045 mL
	60 mM	0.0502 mL	0.2508 mL	0.5015 mL	1.2538 mL
	80 mM	0.0376 mL	0.1881 mL	0.3761 mL	0.9403 mL
	100 mM	0.0301 mL	0.1505 mL	0.3009 mL	0.7523 mL