5-Methoxycarbonylmethyl-2-thiouridine
Based on 1 publication(s) in Google Scholar
5-Methoxycarbonylmethyl-2-thiouridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
For research use only. We do not sell to patients.
- Purity: 99.52%
- CAS No.: 20299-15-4
- Formula: C12H16N2O7S
- Molecular Weight:332.33
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) 5-Methoxycarbonylmethyl-2-thiouridine
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Biological Activity
Chemical Information
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CAS No. 20299-15-4
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Appearance Solid
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Molecular Weight 332.33
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Formula C12H16N2O7S
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Color White to off-white
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SMILES
OC[C@@H]1[C@@H](O)[C@@H](O)[C@H](N(C=C2CC(OC)=O)C(NC2=O)=S)O1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Cell
Adenosine kinase and ADAL coordinate detoxification of modified adenosines to safeguard metabolism. [Abstract]2025 Oct 30;188(22):6151-6169.e24. PMID: 40840445
Solvent & Solubility
DMSO : 100 mg/mL (300.91 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 3.0091 mL | 15.0453 mL | 30.0906 mL | 75.2264 mL |
| 5 mM | 0.6018 mL | 3.0091 mL | 6.0181 mL | 15.0453 mL | |
| 10 mM | 0.3009 mL | 1.5045 mL | 3.0091 mL | 7.5226 mL | |
| 15 mM | 0.2006 mL | 1.0030 mL | 2.0060 mL | 5.0151 mL | |
| 20 mM | 0.1505 mL | 0.7523 mL | 1.5045 mL | 3.7613 mL | |
| 25 mM | 0.1204 mL | 0.6018 mL | 1.2036 mL | 3.0091 mL | |
| 30 mM | 0.1003 mL | 0.5015 mL | 1.0030 mL | 2.5075 mL | |
| 40 mM | 0.0752 mL | 0.3761 mL | 0.7523 mL | 1.8807 mL | |
| 50 mM | 0.0602 mL | 0.3009 mL | 0.6018 mL | 1.5045 mL | |
| 60 mM | 0.0502 mL | 0.2508 mL | 0.5015 mL | 1.2538 mL | |
| 80 mM | 0.0376 mL | 0.1881 mL | 0.3761 mL | 0.9403 mL | |
| 100 mM | 0.0301 mL | 0.1505 mL | 0.3009 mL | 0.7523 mL |
5-Methoxycarbonylmethyl-2-thiouridine Related Classifications
HY-152710 Related Classifications
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