4-Thiothymidine
Based on 1 Customer Validation
4-Thiothymidine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
For research use only. We do not sell to patients.
- Purity: 99.69%
- CAS No.: 7236-57-9
- Formula: C10H14N2O4S
- Molecular Weight:258.29
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Biological Activity
Chemical Information
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CAS No. 7236-57-9
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Appearance Solid
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Molecular Weight 258.29
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Formula C10H14N2O4S
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Color Light yellow to light brown
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SMILES
OC[C@@H]1[C@@H](O)C[C@H](N2C(NC(C(C)=C2)=S)=O)O1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 116.67 mg/mL (451.70 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.8716 mL | 19.3581 mL | 38.7162 mL | 96.7904 mL |
| 5 mM | 0.7743 mL | 3.8716 mL | 7.7432 mL | 19.3581 mL | |
| 10 mM | 0.3872 mL | 1.9358 mL | 3.8716 mL | 9.6790 mL | |
| 15 mM | 0.2581 mL | 1.2905 mL | 2.5811 mL | 6.4527 mL | |
| 20 mM | 0.1936 mL | 0.9679 mL | 1.9358 mL | 4.8395 mL | |
| 25 mM | 0.1549 mL | 0.7743 mL | 1.5486 mL | 3.8716 mL | |
| 30 mM | 0.1291 mL | 0.6453 mL | 1.2905 mL | 3.2263 mL | |
| 40 mM | 0.0968 mL | 0.4840 mL | 0.9679 mL | 2.4198 mL | |
| 50 mM | 0.0774 mL | 0.3872 mL | 0.7743 mL | 1.9358 mL | |
| 60 mM | 0.0645 mL | 0.3226 mL | 0.6453 mL | 1.6132 mL | |
| 80 mM | 0.0484 mL | 0.2420 mL | 0.4840 mL | 1.2099 mL | |
| 100 mM | 0.0387 mL | 0.1936 mL | 0.3872 mL | 0.9679 mL |