44 Results for "

antithrombotic agent

" in MedChemExpress (MCE) Product Catalog:
Products (44)

44 Results for "antithrombotic agent" in MCE Product Catalog:

32
32 Publications Verification
Cat. No.: HY-17459
CAS No.: 120202-66-6
Synonyms: (S)-(+)-Clopidogrel bisulfate; (S)-(+)-Clopidogrel hydrogen sulfate
Research Areas:  

Cardiovascular Disease Cancer

Clopidogrel hydrogen sulfate is an antiplatelet agent to prevent blood clots. Clopidogrel hydrogen sulfate inhibits CYP2B6 and CYP2C19 with IC50s of 18.2 nM and 524 nM, respectively . Clopidogrel hydrogen sulfate is a potent antithrombotic agent that inhibits ADP-induced platelet aggregation .Clopidogrel hydrogen sulfate also is an orally active P2Y(12) inhibitor .
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4
4 Cited Publications
Cat. No.: HY-10274
CAS No.: 211915-06-9
Purity:  99.84%
Synonyms: BIBR 1048
Target:  

Thrombin

Research Areas:  

Cardiovascular Disease

Dabigatran etexilate (BIBR 1048) is an orally active proagent of Dabigatran (a direct inhibitor of thrombin). Dabigatran etexilate has anticoagulant effects and is used for the prophylaxis of venousthromboembolism and stroke due to atrial fibrillation .
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4
4 Cited Publications
Cat. No.: HY-B1271
CAS No.: 57-96-5
Synonyms: G-28315
Sulfinpyrazone (G-28315) is an orally active and potent uricosuric agent for chronic and intermittent gouty arthritis. Sulfinpyrazone has antithrombotic and platelet inhibitory effects .
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4
4 Cited Publications
Cat. No.: HY-10274A
CAS No.: 872728-81-9
Purity:  99.77%
Synonyms: BIBR 1048MS; Dabigatran etexilate methanesulfonate
Target:  

Thrombin

Research Areas:  

Cardiovascular Disease

Dabigatran etexilate mesylate (BIBR 1048MS) is an orally active proagent of Dabigatran (a direct inhibitor of thrombin). Dabigatran etexilate mesylate has anticoagulant effects and is used for the prophylaxis of venousthromboembolism and stroke due to atrial fibrillation .
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1
1 Cited Publications
Cat. No.: HY-112624P
CAS No.: 9004-54-0
Synonyms: Dextran 500; Dextran D500; Dextran T500(MW 440000-560000)
Dextran T500 MW 500,000 (Dextran 500; Dextran D500; Dextran T500 MW 440000-560000) is a polymer of anhydroglucose with the average molecular weight of 500,000. Dextran T500 MW 500,000 exhibits good biodegradability and good biocompatibility, that is utilized in food, pharmaceutics, cosmetics, and research area .
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1
1 Cited Publications
Cat. No.: HY-101054
CAS No.: 130089-98-4
Purity:  98.98%
Target:  

Thrombin

Research Areas:  

Cardiovascular Disease

NQ301 is an antithrombotic agent; inhibits collagen-challenged rabbit platelet aggregation with an IC50 of 10 mg/mL.
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1
1 Cited Publications
Cat. No.: HY-16991
CAS No.: 165538-40-9
Synonyms: S-18886
Terutroban (S-18886) is a selective and orally active thromboxane-prostaglandin (TP) receptor antagonist with an IC50 of 16.4 nM. Terutroban inhibits TXA2 and prostaglandin endoperoxide receptors. Terutroban is a potent antithrombotic agent and possesses anti-atherosclerotic and anti-vasoconstrictor properties .
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1
1 Cited Publications
Cat. No.: HY-16991A
CAS No.: 609340-89-8
Synonyms: S-18886 sodium
Terutroban (S-18886) sodium is a selective and orally active thromboxane-prostaglandin (TP) receptor antagonist with an IC50 of 16.4 nM. Terutroban sodium inhibits TXA2 and prostaglandin endoperoxide receptors. Terutroban sodium is a potent antithrombotic agent and possesses anti-atherosclerotic and anti-vasoconstrictor properties .
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Cat. No.: HY-P2970
CAS No.: 37189-34-7
Stem bromelain (EC 3.4.22.32) is a cysteine protease and antibacterial agent. Stem bromelain can be isolated from the stem of the pineapple (Ananas comosus). Stem bromelain induces dose-dependent secretion of IL-12p70, and IL-6, induces Apoptosis, causes cleavage of full-length PARP protein, Caspase 3, and Caspase 9, increases Bax, and decreases Bcl-2. Stem bromelain possesses various fibrinolytic, antiedema, antithrombotic, and anti-inflammatory activities. Stem bromelain also exhibits in vivo antitumor and antileukemic activities, as well as antimetastatic effects. Stem bromelain has antimycobacterial activity. Stem bromelain provides protection against lead poisoning .
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Cat. No.: HY-129611
CAS No.: 9001-00-7
Target:  

Apoptosis

Research Areas:  

Inflammation/Immunology Cancer

Bromelain is an anti-inflammatory agent derived from pineapple stem that acts through down-regulation of plasma kininogen, inhibition of Prostaglandin E2 expression, degradation of advanced glycation end product receptors and regulation of angiogenic biomarkers as well as antioxidant action upstream in the COX-pathway . Bromelain exhibits various fibrinolytic, antiedematous, antithrombotic, and anti-inflammatory activities. Bromelain also possesses some anticancerous activities and promotes apoptotic cell death .
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Cat. No.: HY-112624D
CAS No.: 9004-54-0
Synonyms: Dextran 60; Dextran D60; Dextran T60(MW 54000-66000)
Dextran T60 MW 60,000 (Dextran 60; Dextran D60; Dextran T60 MW 54000-66000) is a polymer of anhydroglucose with the average molecular weight of 60,000. Dextran T60 MW 60,000 exhibits good biodegradability and good biocompatibility, that is utilized in food, pharmaceutics, cosmetics, and research area .
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Cat. No.: HY-112624Q
CAS No.: 9004-54-0
Synonyms: Dextran 800; Dextran D800; Dextran T800(MW 750000-850000)
Dextran T800 MW 800,000 (Dextran 800; Dextran D800; Dextran T800 MW 750000-850000) is a polymer of anhydroglucose with the average molecular weight of 800,000. Dextran T800 MW 800,000 exhibits good biodegradability and good biocompatibility, that is utilized in food, pharmaceutics, cosmetics, and research area .
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Cat. No.: HY-117290
CAS No.: 1430114-34-3
Purity:  99.33%
Target:  

Factor Xa

Research Areas:  

Cardiovascular Disease

BMS-962212 is a factor XIa (FXIa) inhibitor with a Ki of 0.7 nM against human FXIa and a Ki of 3 nM against rabbit FXIa. BMS-962212 blocks thrombosis while preserving normal hemostatic function. BMS-962212 is applicable to thrombosis-related research .
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Cat. No.: HY-106784
CAS No.: 92285-01-3
Purity:  ≥99.0%
Ajoene, a garlic-derived compound, is an antithrombotic and antifungal agent. Ajoene inhibits proliferation and induces apoptosis of human leukaemia CD34-negative cells including HL-60, U937, HEL and OCIM-I. Anticancer activities .
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Cat. No.: HY-10264S
CAS No.: 1304701-57-2
Purity:  ≥99.0%
Synonyms: DU-176-d6
Edoxaban-d6 is deuterium labeled Edoxaban. Edoxaban (DU-176) is a selective, potent and orally active factor Xa (FXa) inhibitor with Kis of 0.561 nM and 2.98 nM for free FXa and prothrombinase, respectively. Edoxaban is an anticoagulant agent and can be used for stroke prevention. Edoxaban is also a weak inhibitor of thrombin and factor IXaβ (FIXa), with Kis of 6.00 μM and 41.7 μM, respectively, exhibits >10000-fold selectivity for FXa. Edoxaban has antithrombotic properties and has potential for thromboembolic diseases treatment .
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Cat. No.: HY-B1271R
CAS No.: 57-96-5
Synonyms: G-28315 (Standard)
Sulfinpyrazone (Standard) is the analytical standard of Sulfinpyrazone. This product is intended for research and analytical applications. Sulfinpyrazone (G-28315) is an orally active and potent uricosuric agent for chronic and intermittent gouty arthritis. Sulfinpyrazone has antithrombotic and platelet inhibitory effects .
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Cat. No.: HY-P5991
CAS No.: 103951-35-5
Target:  

Peptides

Research Areas:  

Cardiovascular Disease

K-Casein (106-116),bovine is an antithrombotic agent and platelet inhibitor. K-Casein (106-116),bovine binds to platelet αIIbβ3 integrin, thereby preventing fibrinogen binding. K-Casein (106-116),bovine inhibits ADP (HY-W010918)-induced platelet aggregation. K-Casein (106-116),bovine can be used in thrombosis-related research .
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Cat. No.: HY-U00383
CAS No.: 1029711-88-3
Synonyms: 3,3-Dimethylanagrelide
Research Areas:  

Cardiovascular Disease

Rafigrelide is a platelet-lowering agent, and also has antithrombotic properties.
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Cat. No.: HY-129496
CAS No.: 5397-78-4
Purity:  99.58%
Target:  

Thrombin

Research Areas:  

Cardiovascular Disease

NP-313 is a potent antithrombotic agent that inhibits platelet aggregation and activation. NP-313 has dual inhibition of thromboxane A 2 synthesis and selective inhibition of SOCC-mediated Ca 2+ inward flow .
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Cat. No.: HY-10274R
CAS No.: 211915-06-9
Synonyms: BIBR 1048 (Standard)
Research Areas:  

Cardiovascular Disease

Dabigatran etexilate (Standard) is the analytical standard of Dabigatran etexilate. This product is intended for research and analytical applications. Dabigatran etexilate (BIBR 1048) is an orally active proagent of Dabigatran (a direct inhibitor of thrombin). Dabigatran etexilate has anticoagulant effects and is used for the prophylaxis of venousthromboembolism and stroke due to atrial fibrillation .
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