92285-01-3
92285-01-3
Chemical Structure
Ajoene
- CAS No.: 92285-01-3
- Formula:C9H14OS3
- Molecular Weight:234.40
IUPAC Name: (E)-1-allyl-2-(3-(allylsulfinyl)prop-1-en-1-yl)disulfane
InChIKey: IXELFRRANAOWSF-FNORWQNLSA-N
SMILES: O=S(C/C=C/SSCC=C)CC=C
Biological Activity:
Ajoene, a garlic-derived compound, is an antithrombotic and antifungal agent. Ajoene inhibits proliferation and induces apoptosis of human leukaemia CD34-negative cells including HL-60, U937, HEL and OCIM-I. Anticancer activities[1][2].
The product specifications provided below refer solely to the active content of Ajoene.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Ajoene | 98.41% | Ajoene, a garlic-derived compound, is an antithrombotic and antifungal agent. Ajoene inhibits proliferation and induces apoptosis of human leukaemia CD34-negative cells including HL-60, U937, HEL and OCIM-I. Anticancer activities. The product specifications provided below refer solely to the active content of Ajoene. |
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Structural Analogs
-
Similarity Score 1.00
HY-106784A(E)-Ajoene -
Similarity Score 0.73
HY-W015635RDiallyl disulfide (Standard) -
Similarity Score 0.73
HY-117235RDiallyl Trisulfide (Standard) -
Similarity Score 0.72
HY-N9515Diallyl tetrasulfide -
Similarity Score 0.64
HY-134900Allyl methyl trisulfide -
Similarity Score 0.63
HY-W106486Diallyldimethylammonium chloride (60% in water) -
Similarity Score 0.62
HY-W142921SAllyl methyl disulfide-d3 -
Similarity Score 0.61
HY-W018829R10-Undecenal (Standard) -
Similarity Score 0.61
HY-W127515Trans-2,cis-6-Nonadienal -
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References
- [1]. Taylor P, et al. Ajoene inhibits both primary tumor growth and metastasis of B16/BL6 melanoma cells in C57BL/6 mice. Cancer Lett. 2006;239(2):298-304. [Content Brief]
- [2]. Ahmed N, et al. Ajoene, a garlic-derived natural compound, enhances chemotherapy-induced apoptosis in human myeloid leukaemia CD34-positive resistant cells. Anticancer Res. 2001;21(5):3519-3523. [Content Brief]
