92285-01-3
Chemical Structure
Ajoene
- CAS No.: 92285-01-3
- Formula:C9H14OS3
- Molecular Weight:234.40
IUPAC Name: (E)-1-allyl-2-(3-(allylsulfinyl)prop-1-en-1-yl)disulfane
InChIKey: IXELFRRANAOWSF-FNORWQNLSA-N
SMILES: O=S(C/C=C/SSCC=C)CC=C
Biological Activity: Ajoene, a garlic-derived compound, is an antithrombotic and antifungal agent. Ajoene inhibits proliferation and induces apoptosis of human leukaemia CD34-negative cells including HL-60, U937, HEL and OCIM-I. Anticancer activities[1][2].
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Ajoene | 98.41% | Ajoene, a garlic-derived compound, is an antithrombotic and antifungal agent. Ajoene inhibits proliferation and induces apoptosis of human leukaemia CD34-negative cells including HL-60, U937, HEL and OCIM-I. Anticancer activities. | ||||||||||||||||||||
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- [1]. Taylor P, et al. Ajoene inhibits both primary tumor growth and metastasis of B16/BL6 melanoma cells in C57BL/6 mice. Cancer Lett. 2006;239(2):298-304. [Content Brief]
- [2]. Ahmed N, et al. Ajoene, a garlic-derived natural compound, enhances chemotherapy-induced apoptosis in human myeloid leukaemia CD34-positive resistant cells. Anticancer Res. 2001;21(5):3519-3523. [Content Brief]
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