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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
48 Results for "
antitubercular compound
" in MedChemExpress (MCE) Product Catalog:
Products (48)
48 Results for "antitubercular compound" in MCE Product Catalog:
Cat. No.: HY-146120
CAS No.: 1845719-91-6
Antitubercular agent-25 (Compound 28) is an anti-tubercular agent with an extracellular IC50 of 0.42 μM and an intracellular IC50 of 0.20 μM against M. tuberculosis H37Rv. Antitubercular agent-25 exhibits good metabolic stability .
SQ609 is a lead compound from a library of dipiperidines. SQ609 inhibits more than 90% of intracellular bacterial growth at 4μg/ml and is toxic to these cells. SQ609 displays a potent antitubercular activity .
Cat. No.: HY-152138
CAS No.: 2874263-74-6
Antituberculosis agent-8 (Compound 9i) is an antitubercular agent with an MIC of 3.53 μM (1.6 μg/mL) against M. tuberculosis H37Rv. Antituberculosis agent-8 also shows good antifungal activity against A. niger with an MIC of 62.50 μM .
Cat. No.: HY-151960
CAS No.: 2883173-82-6
Antitubercular agent-36 (compound 53) is an antitubercular agent. Antitubercular agent-36 inhibits the growth of MtbH37Rv with a MIC90 value of 1.25 μg/mL. Antitubercular agent-36 can be used for the research of tuberculosis .
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Antitubercular agent-41 (Compound 106) is an antitubercular agent that can be used in the study of Mycobacterium tuberculosis infection .
Cat. No.: HY-146555
CAS No.: 2408627-49-4
Antitubercular agent-14 (Compound 1) is an antitubercular agent with an MIC of 0.3 µg/mL against M. tuberculosis .
Cat. No.: HY-156021
CAS No.: 900314-03-6
Antitubercular agent-40 (compound 93) is a thieno[2,3-b]quinoline-2-carboxamide compound with potential antitubercular activity .
Cat. No.: HY-144721
CAS No.: 3032629-09-4
Antitubercular agent-11 (Compound 1e) is an antitubercular agent. Antitubercular agent-11 with a bulkier electron-donating group (Bu-t) demonstrated the best MIC value of 0.060 μg/mL .
Cat. No.: HY-144722
CAS No.: 905677-04-5
Antitubercular agent-12 (Compound 2c) is an antitubercular agent (MIC = 1.439 μg/mL). Antitubercular agent-12 shows greatly lower cytotoxicity (CC50: 57.34 μg/mL) .
Cat. No.: HY-151957
CAS No.: 2883173-23-5
Antitubercular agent 34 (compound 42g) is an antitubercular agent. Antitubercular agent 34 inhibits the growth of MtbH37Rv with a MIC90 value of 1.25 μg/mL with the ability of escaping metabolic degradation by human liver microsomes. Antitubercular agent 34 can be used for the research of tuberculosis .
Cat. No.: HY-151958
Antitubercular agent-35 (compound 42l) is an antitubercular agent. Antitubercular agent-35 inhibits the growth of MtbH37Rv and M. Marinum with MIC90 values of 1.25 and 2 μg/mL, respectively. Antitubercular agent-35 shows the ability of escaping metabolic degradation by human liver microsomes. Antitubercular agent-35 can be used for the research of tuberculosis .
Cat. No.: HY-155190
CAS No.: 1357796-08-7
Antitubercular agent-39 (Compound P1) is a potent antitubercular agent. Antitubercular agent-39 is active against drug-resistant strains and drug-susceptible clinical isolates. Antitubercular agent-39 inhibits Mtb strain H37Rv with a MIC less than 1 μM .
Cat. No.: HY-163069
Antitubercular agent-43 (compound A11) is an orally active and potent antitubercular agent. Antitubercular agent-43 shows highly metabolic stability against human and mouse cytochrome P450 enzymes. Antitubercular agent-43 exhibits bactericidal efficacy in acute TB infection mouse model .
Cat. No.: HY-151339
CAS No.: 2764818-29-1
Antitubercular agent-31 (Compound 2) is an antitubercular agent with an MIC of 0.03 μM against M. tuberculosis H37Rv. Antitubercular agent-31 also inhibits DprE1 with an IC50 of 1.1 μM .
Cat. No.: HY-146496
CAS No.: 2413124-92-0
Antitubercular agent-20 (Compound 2d) is an orally active antitubercular agent. Antitubercular agent-20 shows excellent activity against MTB H37Rv and MDR-MTB strains (MIC: ＜0.016 µg/ml). Antitubercular agent-20 has low cytotoxicity and good tolerance in BALB/c mice .
Cat. No.: HY-147505
CAS No.: 2412142-93-7
Antitubercular agent-21 (Compound 15) is an antitubercular agent with an MIC of o.4 µg/mL against M. tuberculosis H37Rv. Antitubercular agent-21 exhibits lower activity against other microorganism such as bacteria gram-positive, gram-negative or fungi. Antitubercular agent-21 shows low cytotoxicity .
Cat. No.: HY-146495
CAS No.: 2248171-05-1
Antitubercular agent-19 (Compound 1c) is an antitubercular agent. Antitubercular agent-19 shows excellent activity against MTB H37Rv and MDR-MTB strains (MIC: ＜0.016 µg/ml). Antitubercular agent-19 shows low cytotoxicity and relatively high acute lethal toxicity in BALB/c mice .
Cat. No.: HY-144723
CAS No.: 3032629-25-4
Antitubercular agent-13 (Compound 3d) is an antitubercular agent with MIC values of 0.007 µg/mL and 1.851 µg/mL against MTB H37Rv and MDR-MTB 16833, respectively. Antitubercular agent-13 shows metabolic instability .
Cat. No.: HY-176246
Antitubercular agent-52 (Compound 7k) is an antitubercular agent targeting Mycobacterium tuberculosis (Mtb). Antitubercular agent-52 selectively inhibits the cytochrome bcc (cyt-bcc) electron transport chain of Mtb and also acts on cytochrome bd (cyt-bd). Antitubercular agent-52 blocks electron transfer and ATP production by interfering with the key energy metabolism pathway of Mtb. Antitubercular agent-52 is promising for research of tuberculosis .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
