2248171-05-1
2248171-05-1
Chemical Structure
Antitubercular agent-19
- CAS No.: 2248171-05-1
- Formula:C24H20F6N4O3S
- Molecular Weight:558.50
IUPAC Name: 8-nitro-6-(trifluoromethyl)-2-(2-(4-(trifluoromethyl)benzyl)-2,7-diazaspiro[3.5]nonan-7-yl)-4H-benzo[e][1,3]thiazin-4-one
InChIKey: UUWHUUPBNYIGSP-UHFFFAOYSA-N
SMILES: O=C1N=C(SC2=C(C=C(C=C12)C(F)(F)F)[N+]([O-])=O)N3CCC4(CN(C4)CC5=CC=C(C=C5)C(F)(F)F)CC3
Biological Activity: Antitubercular agent-19 (Compound 1c) is an antitubercular agent. Antitubercular agent-19 shows excellent activity against MTB H37Rv and MDR-MTB strains (MIC: ＜0.016 µg/ml). Antitubercular agent-19 shows low cytotoxicity and relatively high acute lethal toxicity in BALB/c mice[1].
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Antitubercular agent-19 | Antitubercular agent-19 (Compound 1c) is an antitubercular agent. Antitubercular agent-19 shows excellent activity against MTB H37Rv and MDR-MTB strains (MIC: ＜0.016 µg/ml). Antitubercular agent-19 shows low cytotoxicity and relatively high acute lethal toxicity in BALB/c mice. | |||||||||||||||||||||
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