Antitubercular agent-21
Antitubercular agent-21 (Compound 15) is an antitubercular agent with an MIC of o.4 µg/mL against M. tuberculosis H37Rv. Antitubercular agent-21 exhibits lower activity against other microorganism such as bacteria gram-positive, gram-negative or fungi. Antitubercular agent-21 shows low cytotoxicity.
For research use only. We do not sell to patients.
- CAS No.: 2412142-93-7
- Formula: C15H22N6OS
- Molecular Weight:334.44
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| B16-F10 | IC50 |
10.98 μg/mL
Compound: 15
|
Cytotoxicity against mouse B16-F10 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Cytotoxicity against mouse B16-F10 cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 32061963] |
| NHDF | IC50 |
36.18 μg/mL
Compound: 15
|
Cytotoxicity against human NHDF cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
Cytotoxicity against human NHDF cells assessed as reduction in cell viability incubated for 72 hrs by MTT assay
|
[PMID: 32061963] |
Chemical Information
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CAS No. 2412142-93-7
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Molecular Weight 334.44
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Formula C15H22N6OS
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SMILES
N/C(C1=NC=CC(N2CCCC2)=C1)=N\NC(N3CCOCC3)=S
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)