Antitubercular agent-35
Antitubercular agent-35 (compound 42l) is an antitubercular agent. Antitubercular agent-35 inhibits the growth of MtbH37Rv and M. Marinum with MIC90 values of 1.25 and 2 μg/mL, respectively. Antitubercular agent-35 shows the ability of escaping metabolic degradation by human liver microsomes. Antitubercular agent-35 can be used for the research of tuberculosis.
For research use only. We do not sell to patients.
- Formula: C19H13ClN4O2S
- Molecular Weight:396.85
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| THP-1 | IC50 |
>100 μg/mL
Compound: 42l
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Cytotoxicity against human THP-1 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
Cytotoxicity against human THP-1 cells assessed as reduction in cell viability measured after 72 hrs by MTT assay
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[PMID: 36399878] |
Antitubercular agent-35 (0-20 μg/mL; 3-4 d) shows inhibitory effect to MtbH37Rv and M. Marinum with MIC90 values of 1.25 and 2 μg/mL, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 396.85
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Formula C19H13ClN4O2S
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SMILES
O=C(C1=NOC(C2=CSC(NC3=CC=C(C=C3)Cl)=N2)=C1)NC4=CC=CC=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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