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United States

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Cat. No.: HY-146120

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Antitubercular agent-25

Antitubercular agent-25 (Compound 28) is an anti-tubercular agent with an extracellular IC₅₀ of 0.42 μM and an intracellular IC₅₀ of 0.20 μM against M. tuberculosis H37Rv. Antitubercular agent-25 exhibits good metabolic stability.

For research use only. We do not sell to patients.

CAS No.: 1845719-91-6
Formula: C₁₈H₁₆N₄O₃S₂
Molecular Weight:400.47

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (277 KB)

Antitubercular agent-25 Chemical Structure

CAS No.: 1845719-91-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Chemical Information

CAS No. 1845719-91-6
Molecular Weight 400.47
Formula C₁₈H₁₆N₄O₃S₂
SMILES

O=C(C(S1)=CC2=C1N=C(N3CCOCC3)S2)NC4=CC=C(OC(C)=N5)C5=C4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocols

All Cell Biology

Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (277 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Jin G, et al. Discovery of thienothiazolocarboxamide analogues as novel anti-tubercular agent. Bioorg Med Chem. 2020 Dec 1;28(23):115797. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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