2413124-92-0
Chemical Structure
Antitubercular agent-20
- CAS No.: 2413124-92-0
- Formula:C25H22F6N4O3S
- Molecular Weight:572.52
IUPAC Name: 8-nitro-6-(trifluoromethyl)-2-(2-(1-(4-(trifluoromethyl)phenyl)ethyl)-2,7-diazaspiro[3.5]nonan-7-yl)-4H-benzo[e][1,3]thiazin-4-one
InChIKey: RRWKYDLTRHKJBV-UHFFFAOYSA-N
SMILES: CC(N1CC2(C1)CCN(CC2)C3=NC(C4=CC(C(F)(F)F)=CC([N+]([O-])=O)=C4S3)=O)C5=CC=C(C=C5)C(F)(F)F
Biological Activity: Antitubercular agent-20 (Compound 2d) is an orally active antitubercular agent. Antitubercular agent-20 shows excellent activity against MTB H37Rv and MDR-MTB strains (MIC: <0.016 µg/ml). Antitubercular agent-20 has low cytotoxicity and good tolerance in BALB/c mice[1].
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Antitubercular agent-20 | Antitubercular agent-20 (Compound 2d) is an orally active antitubercular agent. Antitubercular agent-20 shows excellent activity against MTB H37Rv and MDR-MTB strains (MIC: <0.016 µg/ml). Antitubercular agent-20 has low cytotoxicity and good tolerance in BALB/c mice. | |||||||||||||||||||||
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Keywords