142 Results for "

boron

" in MedChemExpress (MCE) Product Catalog:
Products (142)

142 Results for "boron" in MCE Product Catalog:

42
42 Publications Verification
Cat. No.: HY-19930
CAS No.: 1360457-46-0
Synonyms: RPX7009
Domaines de recherche:  

Infection

Vaborbactam (RPX7009) is a cyclic boronic acid pharmacophore β-lactamase inhibitor.
29
29 Cited Publications
Cat. No.: HY-141511
CAS No.: 874748-20-6
Pureté:  97.74%
Coppersensor-1 (CS1) is a membrane-permeable fluorescent dye. Coppersensor-1 has a picomolar affinity for Cu + with high selectivity over competing cellular metalions. Coppersensor-1 as a probe, can selective and sensitive detection of copper(I) ions (Cu +) in biological samples, including live cells. Coppersensor-1 can be used for the research of imaging of severe diseases such as cancer, cardiovascular disorders and neurogenerative diseases .
17
17 Cited Publications
Cat. No.: HY-109124
CAS No.: 1613267-49-4
Pureté:  98.45%
Synonyms: VNRX-5133
Domaines de recherche:  

Infection

Taniborbactam (VNRX-5133) is a reversible and selective boronic acid-containing pan-spectrum β-lactamase inhibitor with IC50s of 8-530 nM. Taniborbactam has IC50s of 30 nM, 32 nM, 42 nM, 20 nM for KPC-2, AmpC, OXA-48, and VIM-2. Taniborbactam is against Gram-negative bacteria .
17
17 Cited Publications
Cat. No.: HY-109124A
CAS No.: 2244235-49-0
Pureté:  99.97%
Synonyms: VNRX-5133 hydrochloride
Domaines de recherche:  

Infection

Taniborbactam hydrochloride (VNRX-5133 hydrochloride) is a reversible and selective boronic acid-containing pan-spectrum β-lactamase inhibitor with IC50s of 8-530 nM. Taniborbactam hydrochloride has IC50s of 30 nM, 32 nM, 42 nM, 20 nM for KPC-2, AmpC, OXA-48, and VIM-2. Taniborbactam hydrochloride is against Gram-negative bacteria .
6
6 Cited Publications
Cat. No.: HY-136072
CAS No.: 2170848-99-2
Pureté:  ≥99.0%
Target:  

Bacterial

Domaines de recherche:  

Infection

Xeruborbactam disodium is a potent, ultra-broad-spectrum boronic acid beta-lactamase inhibitor. Xeruborbactam disodium inhibits key serine and metallo beta-lactamases at a nano molar range .
1
1 Cited Publications
Cat. No.: HY-23524
CAS No.: 346656-34-6
Target:  

Lipase

Domaines de recherche:  

Others

HSL-IN-3, a boronic acid ester derivative, is an inhibitor of hormone-sensitive lipase (HSL) .
1
1 Cited Publications
Cat. No.: HY-D1553
CAS No.: 1029138-21-3
BODIPY-C12 is a boron-dipyrromethene derivative containing a lipophilic tail (excitation 490 nm). BODIPY-C12 is a hydrophobic molecular and sensitivity to the surrounding environment and can be used to quantify viscosity, critical micelle concentration, and critical micelle temperature .
1
1 Cited Publications
Cat. No.: HY-139606
CAS No.: 2630950-38-6
Target:  

p97

Domaines de recherche:  

Cancer

VCP/p97 inhibitor-1 is a potent inhibitor of VCP/p97 (also called Cdc48, CDC-. 48, or Ter94) with an IC50 of 54.7 nM. VCP/p97 inhibitor-1 causes the dysregulation of protein homeostasis and disturbs the degradation of misfolded polypeptides by the ubiquitin-proteasome system (UPS) .
Cat. No.: HY-142041
CAS No.: 144885-51-8
Pureté:  ≥95.0%
Synonyms: BSH
Domaines de recherche:  

Cancer

Borocaptate sodium is a boron-containing compound that can be used as a therapeutic agent in boron neutron capture therapy (BNCT), exhibiting anticancer activity .
Cat. No.: HY-W087830
CAS No.: 76410-58-7
Synonyms: L-BPA
L-p-Boronophenylalanine is a boron-containing substrate for L-type amino acid transporters (LAT1 and LAT2). L-p-Boronophenylalanine enters tumor cells by competing with natural amino acids for LAT, selectively accumulating boron in cancer cells. L-p-Boronophenylalanine can be used in boron neutron capture therapy (BNCT). When boron-10 captures thermal neutrons, a nuclear reaction occurs, producing high-energy alpha particles and lithium nuclei, which kill cancer cells at close range with little damage to surrounding tissues. L-p-Boronophenylalanine can be used in cancer research, especially glioblastoma and anaplastic astrocytoma .
Cat. No.: HY-W116606
CAS No.: 1357078-03-5
Target:  

Fluorescent Dye

Domaines de recherche:  

Others

Coumarin boronic acid is a fluorescent probe. The excitation and emission wavelengths of coumarin boronic acid are set to 360 nm and 430 nm, respectively. Coumarin boronic acid can be used to monitor the formation of amino acid and protein hydroxyl peroxides in real time, which is beneficial for understanding the mechanisms of oxidative stress and protein post-translational modification .
Cat. No.: HY-40249
CAS No.: 286961-14-6
1-Boc-1,2,3,6-tetrahydropyridine-4-boronic acid pinacol ester is a drug intermediate that can be used for the preparation of SMARCA bromodomain ligands .
Cat. No.: HY-W025784
CAS No.: 143-66-8
Synonyms: Sodium tetraphenylborate; Tetraphenylboron sodium
Kalibor (Sodium tetraphenylborate; Tetraphenylboron sodium) is a boron-based salt and antibacterial agent. Kalibor exerts activity against Neisseria meningitidis and Neisseria gonorrhoeae. Kalibor facilitates boron uptake by Neisseria meningitidis cells. Kalibor reduces bacterial burden in a mouse model of Neisseria meningitidis bacteremia. Kalibor can be used for the research of bacterial infection, such as meningococcal bacteremia .
Cat. No.: HY-I0308
CAS No.: 761446-44-0
1-Methyl-1H-pyrazole-4-boronic acid pinacol ester is an organic synthetic intermediate, which can be used to synthesize other active compounds .
Cat. No.: HY-W000903
CAS No.: 244205-40-1
(2-Bromophenyl)boronic acid is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Cat. No.: HY-W001242
CAS No.: 903550-26-5
1-(Tetrahydropyran-2-yl)-1H-pyrazole-5-boronic acid pinacol ester is a pharmaceutical intermediate used in the synthesis of naphthyl FXIa/PKa inhibitors .
Cat. No.: HY-32951
CAS No.: 401815-98-3
2-Fluoropyridine-4-boronic acid is a coupling reagent and chemical intermediate. 2-Fluoropyridine-4-boronic acid facilitates the synthesis of Rho kinase (ROCK) inhibitor Compound 37 .
Cat. No.: HY-114376
CAS No.: 12448-24-7
Synonyms: BSH-10B12
Borocaptate-10B12 (BSH-10B12) sodium is a boron-10 labeled Borocaptate (HY-142041). Borocaptate sodium is a boron-containing compound that can be used as a therapeutic agent in boron neutron capture therapy (BNCT), exhibiting anticancer activity .
Cat. No.: HY-32685
CAS No.: 286961-15-7
N-Cbz-1,2,3,6-tetrahydropyridine-4-boronic acid pinacol ester is a biochemical reagent.
Cat. No.: HY-I0314
CAS No.: 269410-08-4
1H-Pyrazole-4-boronic acid pinacol ester is a drug intermediate that can be used for the synthesis of Mps1 kinase inhibitors .