Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
43 Results for "
coordinating
" in MedChemExpress (MCE) Product Catalog:
Products (43)
43 Results for "coordinating" in MCE Product Catalog:
4
4 Cited Publications
Art. -Nr.: HY-W115718
CAS. Nr.: 370-81-0
Target:
Forschungsgebiete:
Cuprizone is a copper chelating agent that forms a deep blue copper ketone complex with copper (II). The copper ketone reaction can be used in colorimetric tests for the presence of trace copper. Cuprizone can be used to induce some schizophrenia-like behavior in mice. Cuprizone acts on copper enzymes, including SOD1, cytochrome oxidase, and DβH, thereby causing oxidative stress and increasing DA levels in certain brain regions such as the medial prefrontal cortex (PFC) .
4
Target:
2
Target:
1
Target:
1
1 Cited Publications
Target:
Forschungsgebiete:
SBI-477 is a chemical probe that stimulates insulin signaling by deactivating the transcription factor MondoA. SBI-477 can lead to reduced expression of the insulin pathway suppressors thioredoxin-interacting protein (TXNIP) and arrestin domain-containing 4 (ARRDC4). SBI-477 coordinately inhibits triacylglyceride (TAG) synthesis and enhances basal glucose uptake in human skeletal myocytes .
Art. -Nr.: HY-147295
CAS. Nr.: 53238-80-5
Synonyms: BTH 1677; Imprime PGG
Forschungsgebiete:
Odetiglucan is a novel β-glucan that is a potent immunostimulant and a Dectin-1 (CLEC7A) agonist. Odetiglucan activates innate immune effector cells and triggers a coordinated anti-cancer immune response .
Art. -Nr.: HY-W008806
CAS. Nr.: 143537-62-6
Synonyms: OHHL; N-(3-Oxohexanoyl)homoserine lactone
Target:
Forschungsgebiete:
N-(3-Oxohexanoyl)-L-homoserine lactone (OHHL; N-(3-Oxohexanoyl)homoserine lactone) is a specific agonist of LuxR-type transcription factor CarR with a Kd of 1.8 μM. N-(3-Oxohexanoyl)-L-homoserine lactone activates CarR by inducing protein multimerization, promoting its binding to target DNA sequences in the carR-carA intergenic region, thereby upregulating the transcription of carbapenem biosynthesis genes. N-(3-Oxohexanoyl)-L-homoserine lactone acts as a quorum sensing signal molecule, enabling bacteria to coordinate the production of carbapenem antibiotics in a cell density-dependent manner. N-(3-Oxohexanoyl)-L-homoserine lactone is used to study bacterial quorum sensing mechanisms, especially the secondary metabolism and virulence factor regulatory pathways of Erwinia carotovora and Yersinia enterocolitica .
Art. -Nr.: HY-W127776
CAS. Nr.: 176736-49-5
Synonyms: Ethylenediaminetetraacetic acid zinc disodium tetrahydrate
Art. -Nr.: HY-W040240
CAS. Nr.: 87-79-6
Target:
Art. -Nr.: HY-W015302
CAS. Nr.: 88-21-1
Synonyms: Orthanilic acid; 2-Aminobenzenesulphonic acid
Target:
Art. -Nr.: HY-W048682
CAS. Nr.: 202920-22-7
Target:
Forschungsgebiete:
Fmoc-1-methyl-L-histidine is an Fmoc-protected amino acid as well as an amino acid-containing building block. Fmoc-1-methyl-L-histidine is applicable to the generation of the ε-nitrogen-coordinated copper center in nitrite copper reductase. It also serves as an intermediate in peptide synthesis .
Art. -Nr.: HY-115853
CAS. Nr.: 78668-34-5
Target:
Forschungsgebiete:
Pyclen forms kinetically and thermodynamically stable nine-coordinate Ln (III) complexes, as well as Mn (II)-based MRI contrast agents. Pyclen-Based Mn(II) Complexes can be used for liver-specific MRI .
Art. -Nr.: HY-W003836
CAS. Nr.: 6836-22-2
Synonyms: 7-Methoxy-NAA
Target:
Forschungsgebiete:
7-Methyl-1-naphthyl acetic acid is a potent
inhibitor of auxin action in plants. 7-Methyl-1-naphthyl acetic acid inhibits
AUX1, PIN, and ABCB protein-mediated auxin transport expressed in yeast.
7-Methyl-1-naphthyl acetic acid can be used in auxin dependent development
.
Art. -Nr.: HY-W145481A
CAS. Nr.: 11078-30-1
Synonyms: Carob galactomannan
Art. -Nr.: HY-P5372A
Forschungsgebiete:
Art. -Nr.: HY-W115718R
CAS. Nr.: 370-81-0
Forschungsgebiete:
Cuprizone is a copper chelating agent that forms a deep blue copper ketone complex with copper (II). The copper ketone reaction can be used in colorimetric tests for the presence of trace copper. Cuprizone can be used to induce some schizophrenia-like behavior in mice. Cuprizone acts on copper enzymes, including SOD1, cytochrome oxidase, and DβH, thereby causing oxidative stress and increasing DA levels in certain brain regions such as the medial prefrontal cortex (PFC) .
Art. -Nr.: HY-B1306S
CAS. Nr.: 1219805-41-0
Synonyms: p-Aminohippuric acid-d4
Art. -Nr.: HY-W127393
CAS. Nr.: 177158-21-3
Art. -Nr.: HY-161998
CAS. Nr.: 1203704-26-0
Urease-IN-16 (compound 4e) is a urease inhibitor, with an IC50 value of 132 μmol/L. Urease-IN-16 can coordinate with the nickel atom through the oxygen atoms of carbonyl or boronic acid groups. Urease-IN-16 shows great potential as an additive in the development of efficient fertilizers and medical applications .
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
