cosolvent

By Targets:	Apoptosis (2) Bacterial (2) Biochemical Assay Reagents (7) Endogenous Metabolite (2) Environmental Pollutants (3) Fluorescent Dye (3) Reference Standards (1)
By Research Areas:	Cancer (2) Cardiovascular Disease (2) Infection (2)
Click Chemistry:	Azide (1)
Oligonucleotides:	Release-retarding Agents (1) Solvents (1) Thickeners (1)

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D0819

CY5-SE 35+ Cited Publications Cy5 NHS Ester; Sulfo-Cyanine5 Succinimidyl Ester	Fluorescent Dye	Others
Cy5-SE (Cy5 NHS Ester) is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. This dye requires small amount of organic co-solvent (such as DMF or DMSO) to be used in labeling reaction. This reagent is ideal for very cost-efficient labeling of soluble proteins, as well as all kinds of peptides and oligonucleotides. This reagent also works well in organic solvents for small molecule labeling. Excitation (nm):649, Emission (nm): 670.

HY-126403

Ethoxylated hydrogenated castor oil 2 Publications Verification PEG-40 hydrogenated castor oil; Macrogolglycerol hydroxystearate; Castor oil, hydrogenated, polyethoxylated	Environmental Pollutants Biochemical Assay Reagents	Others
Ethoxylated hydrogenated castor oil (PEG-40 hydrogenated castor oil) is a combination of synthetic polyethylene glycol (PEG) with natural castor oil. Ethoxylated hydrogenated castor oil can be used to emulsify and solubilize oil-in-water (o/w) emulsions. Ethoxylated hydrogenated castor oil can be used as a cosolvent in vivo .

HY-B1610

Sodium citrate dihydrate 10+ Cited Publications Trisodium citrate dihydrate; Citric acid trisodium salt dihydrate	Environmental Pollutants Endogenous Metabolite Apoptosis Bacterial	Infection Cardiovascular Disease Cancer
Sodium citrate dehydrate (Trisodium citrate dihydrate) is a natural product with oral activity that can be found in citrus fruits. Sodium citrate dehydrate can inhibit the proliferation of tumor cells and induce apoptosis. Sodium citrate dehydrate has antibacterial, anti-tumor and antioxidant activities. Sodium citrate dehydrate can be prepared as a cosolvent or buffer .

HY-107799

Castor oil 5 Publications Verification	Environmental Pollutants Biochemical Assay Reagents	Others
Castor oil is a natural triglyceride and a solvent. Castor oil has a laxative effect and induces labor in pregnant females. Castor oil can be used as a solvent, co-solvent, stabilizing agent and polyol for the formation of polymer-nanoparticle composites .

HY-152927

Hydroxypropylmethyl cellulose acetate succinate (Mw: 20-100k Da)	Biochemical Assay Reagents	Others
Hydroxypropylmethyl cellulose acetate succinate (Mw: 20-100k Da) is a cosolvent for preparing SDDs of low-solubility agents. Hydroxypropylmethyl cellulose acetate succinate (Mw: 20-100k Da) exhibits no acute/subchronic/chronic toxicity in rats, with oral activity and LD₅₀ >2.5 g/kg .

HY-Y1078

DMF-DMA N-Dimethoxymethyl-N,N-dimethylamine	Biochemical Assay Reagents	Others
DMF-DMA (N-Dimethoxymethyl-N,N-dimethylamine) is a reagent with both condensation and alkylation functions. DMF-DMA can undergo condensation reactions with active methylene groups or amino groups to generate enamine and imino derivatives, and can also act as an alkylating agent to methylate nitrogen and oxygen atoms in heterocyclic structures. DMF-DMA is widely used in the synthesis of enaminones and dimethylamino imine intermediates, as well as in the construction of heterocyclic backbones such as pyridine, pyrimidine and pyrazole. DMF-DMA can also serve as a polar aprotic co-solvent; although DMF-DMA cannot dissolve cellulose alone, it can form an efficient cellulose dissolution system with diallylimidazolium methoxyacetate .

HY-W145493

Glycofurol Tetraglycol; Poly(ethylene glycol) tetrahydrofurfuryl ether	Biochemical Assay Reagents	Others
Glycofurol (Tetraglycol) is a hydrophilic, water-miscible cosolvent and absorption enhancer with skin tolerance. Glycofurol can be used as a carrier-based gel for the topical delivery of drugs, including water-insoluble drugs. Glycofurol can form gels with bioadhesiveness, spreadability and suitable viscosity for topical administration .

HY-DY1063

CY5-SE (solution)	Fluorescent Dye	Others
Cy5-SE (Cy5 NHS Ester) (solution) is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. This dye requires small amount of organic co-solvent (such as DMF or DMSO) to be used in labeling reaction. This reagent is ideal for very cost-efficient labeling of soluble proteins, as well as all kinds of peptides and oligonucleotides. This reagent also works well in organic solvents for small molecule labeling. Excitation (nm) :649, Emission (nm) : 670. Solvent and concentration: DMSO: 10 mM

HY-Y1911

Mid-chain triglyceride of caprylic/caprolic acid	Biochemical Assay Reagents	Others
Mid-chain triglyceride of caprylic/caprolic acid can be used as a co-solvent.

HY-B1610R

Sodium citrate dihydrate (Standard) Trisodium citrate dihydrate (Standard); Citric acid trisodium salt dihydrate (Standard)	Reference Standards Bacterial Endogenous Metabolite Apoptosis	Infection Cardiovascular Disease Cancer
Sodium citrate (dihydrate) (Standard) is the analytical standard of Sodium citrate (dihydrate). This product is intended for research and analytical applications. Sodium citrate dehydrate (Trisodium citrate dihydrate) is a natural product with oral activity that can be found in citrus fruits. Sodium citrate dehydrate can inhibit the proliferation of tumor cells and induce apoptosis. Sodium citrate dehydrate has antibacterial, anti-tumor and antioxidant activities. Sodium citrate dehydrate can be prepared as a cosolvent or buffer .

HY-W738314

Heptakis(6-O-tert-butyldimethylsilyl)-β-cyclodextrin tetradecaacetate	Biochemical Assay Reagents
Heptakis(6-O-tert-butyldimethylsilyl)-β-cyclodextrin tetradecaacetate is a chemically modified cyclodextrin with good cosolvent activity. Heptakis(6-O-tert-butyldimethylsilyl)-β-cyclodextrin tetradecaacetate is widely used in compound formulations to improve the solubility and bioavailability of compounds. Heptakis(6-O-tert-butyldimethylsilyl)-β-cyclodextrin tetradecaacetate helps improve the release characteristics of compounds.

HY-D2759

Cyanine3B azide	Fluorescent Dye	Others
Cyanine3B azide for click chemistry conjugation with terminal alkynes via a copper-catalyzed click reaction or strained cyclooctynes via a copper-free click reaction. Cyanine3B is a yellow-emitting cyanine dye that is an improved version of the Cyanine3 fluorophore with significantly higher fluorescence quantum yield and photostability. Due to the fixed conformation, Cyanine3B has the highest emission quantum yield compared to other dyes of this wavelength. This is a non-sulfonated dye that requires an organic co-solvent (DMF, DMSO, or other) for efficient labeling in water.

Cat. No.	Product Name	Type

HY-D0819

CY5-SE 35+ Cited Publications Cy5 NHS Ester; Sulfo-Cyanine5 Succinimidyl Ester	Fluorescent Dye
Cy5-SE (Cy5 NHS Ester) is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. This dye requires small amount of organic co-solvent (such as DMF or DMSO) to be used in labeling reaction. This reagent is ideal for very cost-efficient labeling of soluble proteins, as well as all kinds of peptides and oligonucleotides. This reagent also works well in organic solvents for small molecule labeling. Excitation (nm):649, Emission (nm): 670.

CY5-SE

35+ Cited Publications

Cy5 NHS Ester; Sulfo-Cyanine5 Succinimidyl Ester

Fluorescent Dye

Cy5-SE (Cy5 NHS Ester) is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. This dye requires small amount of organic co-solvent (such as DMF or DMSO) to be used in labeling reaction. This reagent is ideal for very cost-efficient labeling of soluble proteins, as well as all kinds of peptides and oligonucleotides. This reagent also works well in organic solvents for small molecule labeling. Excitation (nm):649, Emission (nm): 670.

HY-DY1063

CY5-SE (solution)	Fluorescent Dye
Cy5-SE (Cy5 NHS Ester) (solution) is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. This dye requires small amount of organic co-solvent (such as DMF or DMSO) to be used in labeling reaction. This reagent is ideal for very cost-efficient labeling of soluble proteins, as well as all kinds of peptides and oligonucleotides. This reagent also works well in organic solvents for small molecule labeling. Excitation (nm) :649, Emission (nm) : 670. Solvent and concentration: DMSO: 10 mM

CY5-SE (solution)

Fluorescent Dye

Cy5-SE (Cy5 NHS Ester) (solution) is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. This dye requires small amount of organic co-solvent (such as DMF or DMSO) to be used in labeling reaction. This reagent is ideal for very cost-efficient labeling of soluble proteins, as well as all kinds of peptides and oligonucleotides. This reagent also works well in organic solvents for small molecule labeling. Excitation (nm) :649, Emission (nm) : 670.
Solvent and concentration: DMSO: 10 mM

HY-D2759

Cyanine3B azide	Fluorescent Dye
Cyanine3B azide for click chemistry conjugation with terminal alkynes via a copper-catalyzed click reaction or strained cyclooctynes via a copper-free click reaction. Cyanine3B is a yellow-emitting cyanine dye that is an improved version of the Cyanine3 fluorophore with significantly higher fluorescence quantum yield and photostability. Due to the fixed conformation, Cyanine3B has the highest emission quantum yield compared to other dyes of this wavelength. This is a non-sulfonated dye that requires an organic co-solvent (DMF, DMSO, or other) for efficient labeling in water.

Cyanine3B azide

Fluorescent Dye

Cyanine3B azide for click chemistry conjugation with terminal alkynes via a copper-catalyzed click reaction or strained cyclooctynes via a copper-free click reaction. Cyanine3B is a yellow-emitting cyanine dye that is an improved version of the Cyanine3 fluorophore with significantly higher fluorescence quantum yield and photostability. Due to the fixed conformation, Cyanine3B has the highest emission quantum yield compared to other dyes of this wavelength. This is a non-sulfonated dye that requires an organic co-solvent (DMF, DMSO, or other) for efficient labeling in water.

Cat. No.	Product Name	Type

HY-126403

Ethoxylated hydrogenated castor oil 2 Publications Verification PEG-40 hydrogenated castor oil; Macrogolglycerol hydroxystearate; Castor oil, hydrogenated, polyethoxylated	Biochemical Assay Reagents
Ethoxylated hydrogenated castor oil (PEG-40 hydrogenated castor oil) is a combination of synthetic polyethylene glycol (PEG) with natural castor oil. Ethoxylated hydrogenated castor oil can be used to emulsify and solubilize oil-in-water (o/w) emulsions. Ethoxylated hydrogenated castor oil can be used as a cosolvent in vivo .

HY-107799

Castor oil 5 Publications Verification	Biochemical Assay Reagents
Castor oil is a natural triglyceride and a solvent. Castor oil has a laxative effect and induces labor in pregnant females. Castor oil can be used as a solvent, co-solvent, stabilizing agent and polyol for the formation of polymer-nanoparticle composites .

HY-W145493

Glycofurol Tetraglycol; Poly(ethylene glycol) tetrahydrofurfuryl ether	Biochemical Assay Reagents
Glycofurol (Tetraglycol) is a hydrophilic, water-miscible cosolvent and absorption enhancer with skin tolerance. Glycofurol can be used as a carrier-based gel for the topical delivery of drugs, including water-insoluble drugs. Glycofurol can form gels with bioadhesiveness, spreadability and suitable viscosity for topical administration .

HY-Y1911

Mid-chain triglyceride of caprylic/caprolic acid	Biochemical Assay Reagents
Mid-chain triglyceride of caprylic/caprolic acid can be used as a co-solvent.

HY-W738314

Heptakis(6-O-tert-butyldimethylsilyl)-β-cyclodextrin tetradecaacetate	Biochemical Assay Reagents
Heptakis(6-O-tert-butyldimethylsilyl)-β-cyclodextrin tetradecaacetate is a chemically modified cyclodextrin with good cosolvent activity. Heptakis(6-O-tert-butyldimethylsilyl)-β-cyclodextrin tetradecaacetate is widely used in compound formulations to improve the solubility and bioavailability of compounds. Heptakis(6-O-tert-butyldimethylsilyl)-β-cyclodextrin tetradecaacetate helps improve the release characteristics of compounds.

Heptakis(6-O-tert-butyldimethylsilyl)-β-cyclodextrin tetradecaacetate

Biochemical Assay Reagents

Heptakis(6-O-tert-butyldimethylsilyl)-β-cyclodextrin tetradecaacetate is a chemically modified cyclodextrin with good cosolvent activity. Heptakis(6-O-tert-butyldimethylsilyl)-β-cyclodextrin tetradecaacetate is widely used in compound formulations to improve the solubility and bioavailability of compounds. Heptakis(6-O-tert-butyldimethylsilyl)-β-cyclodextrin tetradecaacetate helps improve the release characteristics of compounds.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B1610

Sodium citrate dihydrate 10+ Cited Publications Trisodium citrate dihydrate; Citric acid trisodium salt dihydrate	Cardiovascular Disease Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Source Classification	Environmental Pollutants Endogenous Metabolite Apoptosis Bacterial
Sodium citrate dehydrate (Trisodium citrate dihydrate) is a natural product with oral activity that can be found in citrus fruits. Sodium citrate dehydrate can inhibit the proliferation of tumor cells and induce apoptosis. Sodium citrate dehydrate has antibacterial, anti-tumor and antioxidant activities. Sodium citrate dehydrate can be prepared as a cosolvent or buffer .

HY-B1610R

Sodium citrate dihydrate (Standard) Trisodium citrate dihydrate (Standard); Citric acid trisodium salt dihydrate (Standard)	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Bacterial Endogenous Metabolite Apoptosis
Sodium citrate (dihydrate) (Standard) is the analytical standard of Sodium citrate (dihydrate). This product is intended for research and analytical applications. Sodium citrate dehydrate (Trisodium citrate dihydrate) is a natural product with oral activity that can be found in citrus fruits. Sodium citrate dehydrate can inhibit the proliferation of tumor cells and induce apoptosis. Sodium citrate dehydrate has antibacterial, anti-tumor and antioxidant activities. Sodium citrate dehydrate can be prepared as a cosolvent or buffer .

Cat. No.	Product Name		Classification

HY-D2759

Cyanine3B azide		Azide
Cyanine3B azide for click chemistry conjugation with terminal alkynes via a copper-catalyzed click reaction or strained cyclooctynes via a copper-free click reaction. Cyanine3B is a yellow-emitting cyanine dye that is an improved version of the Cyanine3 fluorophore with significantly higher fluorescence quantum yield and photostability. Due to the fixed conformation, Cyanine3B has the highest emission quantum yield compared to other dyes of this wavelength. This is a non-sulfonated dye that requires an organic co-solvent (DMF, DMSO, or other) for efficient labeling in water.

Cat. No.	Product Name		Classification

HY-126403

Ethoxylated hydrogenated castor oil 2 Publications Verification PEG-40 hydrogenated castor oil; Macrogolglycerol hydroxystearate; Castor oil, hydrogenated, polyethoxylated		Thickeners
Ethoxylated hydrogenated castor oil (PEG-40 hydrogenated castor oil) is a combination of synthetic polyethylene glycol (PEG) with natural castor oil. Ethoxylated hydrogenated castor oil can be used to emulsify and solubilize oil-in-water (o/w) emulsions. Ethoxylated hydrogenated castor oil can be used as a cosolvent in vivo .

HY-107799

Castor oil 5 Publications Verification		Solvents
Castor oil is a natural triglyceride and a solvent. Castor oil has a laxative effect and induces labor in pregnant females. Castor oil can be used as a solvent, co-solvent, stabilizing agent and polyol for the formation of polymer-nanoparticle composites .

HY-152927

Hydroxypropylmethyl cellulose acetate succinate (Mw: 20-100k Da)		Release-retarding Agents
Hydroxypropylmethyl cellulose acetate succinate (Mw: 20-100k Da) is a cosolvent for preparing SDDs of low-solubility agents. Hydroxypropylmethyl cellulose acetate succinate (Mw: 20-100k Da) exhibits no acute/subchronic/chronic toxicity in rats, with oral activity and LD₅₀ >2.5 g/kg .

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
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cosolvent

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Fluorescent Dye

Biochemical Assay Reagents

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Click Chemistry

Oligonucleotides

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