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Ethoxylated hydrogenated castor oil (Synonyms: PEG-40 hydrogenated castor oil; Macrogolglycerol hydroxystearate; Castor oil, hydrogenated, polyethoxylated)

Cat. No.: HY-126403
Handling Instructions

Ethoxylated hydrogenated castor oil (PEG-40 hydrogenated castor oil) is a combination of synthetic polyethylene glycol (PEG) with natural castor oil. Ethoxylated hydrogenated castor oil can be used to emulsify and solubilize oil-in-water (o/w) emulsions. Ethoxylated hydrogenated castor oil can be used as a cosolvent in vivo.

For research use only. We do not sell to patients.

Ethoxylated hydrogenated castor oil Chemical Structure

Ethoxylated hydrogenated castor oil Chemical Structure

CAS No. : 61788-85-0

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Estimated Time of Arrival: December 31
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Description

Ethoxylated hydrogenated castor oil (PEG-40 hydrogenated castor oil) is a combination of synthetic polyethylene glycol (PEG) with natural castor oil. Ethoxylated hydrogenated castor oil can be used to emulsify and solubilize oil-in-water (o/w) emulsions. Ethoxylated hydrogenated castor oil can be used as a cosolvent in vivo[1].

In Vivo

20% PEG-40 hydrogenated castor oil (10 μl) is applied to the left ear of the mouse, and the right ear served as a control. The mice are observed for development of erthyma for 6 days, no signs of irritation are observed in the mice[1].
PEG-40 hydrogenated castor oil (injection via the tail vein; 300, 900, and 2700 mg/kg; 4 weeks) is administared for short-term toxicity. At doses of 300 and 900 mg/kg PEG-40 Hydrogenated Castor Oi exhibits no systemic toxicity. However, at a dose of 2700 mg/kg, slight ataxia is observed and body weight is reduced significantly in the males and slightly in the females[1].
A toxicity study of blank nanoemulsion using PEG-40 hydrogenated castor oil as a surfactant is applied in order to load various active compounds for oral administration[2].
Nearly 20% of PEG-40 hydrogenated castor oil was used to emulsify the glyceryl monooleate (GMO) as an oil to the aqueous phase. In Webster mice, 5000 mg/kg blank nanoemulsion is given orally to mice once a day for 14 days, this nanoemulsion does not produce hazardous effects, and it has no effect on food intake[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

CAS No.

61788-85-0

SMILES

[Ethoxylated hydrogenated castor oil]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

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Keywords:

Ethoxylated hydrogenated castor oilPEG-40 hydrogenated castor oil Macrogolglycerol hydroxystearate Castor oil, hydrogenated, polyethoxylatedOthersemulsioncosolventPEGInhibitorinhibitorinhibit

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Product Name:
Ethoxylated hydrogenated castor oil
Cat. No.:
HY-126403
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