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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
dCTPase
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "dCTPase" in MCE Product Catalog:
3
3 Cited Publications
Cat. No.: HY-16965
CAS No.: 1609960-30-6
Target:
Research Areas:
TH287 is a potent and selective inhibitor of MTH1, with an IC50 of 0.8 nM. TH287 is highly selective towards MTH1, with no relevant inhibition of MTH2, NUDT5, NUDT12, NUDT14, NUDT16, dCTPase, dUTPase and ITPA at 100 μM. TH287 could act as a chemotherapeutic agent for cancer research .
1
1 Cited Publications
Synonyms: ZINC1775962367
TH1217 (ZINC1775962367) is a potent and selective dCTPase pyrophosphatase 1 (dCTPase) inhibitor, with an IC50 of 47 nM. TH1217 enhances the cytotoxic effect of cytidine analogues in leukemia cells. TH1217 also could modulate SARS-Cov-2 interactors, so it shows activity of against COVID-19 .
Cat. No.: HY-W551344
CAS No.: 353287-72-6
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Research Areas:
dCTPase-IN-1 is a highly selective deoxycytidine triphosphate pyrophosphatase 1 (dCTPase) inhibitor with an IC50 of 20 nM. dCTPase-IN-1 functionally inhibits dCTPase, exhibits a synergistic effect in enhancing cytotoxicity, and has no inherent cytotoxicity. dCTPase-IN-1 can be used for the research of leukemia .
Cat. No.: HY-16965A
CAS No.: 1638211-05-8
Target:
Research Areas:
TH287 hydrochloride is a potent and selective inhibitor of MTH1, with an IC50 of 0.8 nM. TH287 hydrochloride is highly selective towards MTH1, with no relevant inhibition of MTH2, NUDT5, NUDT12, NUDT14, NUDT16, dCTPase, dUTPase and ITPA at 100 μM. TH287 hydrochloride could act as a chemotherapeutic agent for cancer research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
