353287-72-6
Chemical Structure
dCTPase-IN-1
- CAS No.: 353287-72-6
- Formula:C15H12N4O2S2
- Molecular Weight:344.41
IUPAC Name: 6-(3,4-dimethoxyphenyl)-3-(thiophen-2-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole
InChIKey: YTGYWPTWNBGCLG-UHFFFAOYSA-N
SMILES: N=1N=C(C=2SC=CC2)N3N=C(SC13)C=4C=CC(OC)=C(OC)C4
Biological Activity: dCTPase-IN-1 is a highly selective deoxycytidine triphosphate pyrophosphatase 1 (dCTPase) inhibitor with an IC50 of 20 nM. dCTPase-IN-1 functionally inhibits dCTPase, exhibits a synergistic effect in enhancing cytotoxicity, and has no inherent cytotoxicity. dCTPase-IN-1 can be used for the research of leukemia[1].
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dCTPase-IN-1 | dCTPase-IN-1 is a highly selective deoxycytidine triphosphate pyrophosphatase 1 (dCTPase) inhibitor with an IC50 of 20 nM. dCTPase-IN-1 functionally inhibits dCTPase, exhibits a synergistic effect in enhancing cytotoxicity, and has no inherent cytotoxicity. dCTPase-IN-1 can be used for the research of leukemia. | |||||||||||||||||||||
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Keywords
