10 Results for "

dTMP

" in MedChemExpress (MCE) Product Catalog:
Products (10)

10 Results for "dTMP" in MCE Product Catalog:

Cat. No.: HY-W011142
CAS No.: 42155-08-8
Synonyms: dUMP disodium
2'-Deoxyuridine 5'-monophosphate (dUMP) disodium is a deoxynucleotide that is reductively methylated to dTMP (2'-deoxythymidine 5'-monophosphate) by bisubstrate enzyme thymidylate synthase (TS). dTMP is a nucleotide required for DNA synthesis .
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Cat. No.: HY-131576A
CAS No.: 108322-12-9
Purity:  ≥98.0%
Synonyms: dTDP sodium
Thymidine 5′-diphosphate (dTDP) sodium is the key product of pyrimidine synthesis in organisms. Thymidine 5′-diphosphate sodium is produced by thymidylate kinase (TMPK) catalyzed phosphorylation of 5′-thymidine monophosphate (dTMP), which requires ATP and Mg 2+. Thymidine 5′-diphosphate sodium is further catalyzed by TMPK to thymidine 5′-triphosphate (dTTP). TMPK activity can be detected by measuring the level of Thymidine 5′-diphosphate .
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Cat. No.: HY-W587663
CAS No.: 21253-58-7
Research Areas:  

Infection

4 '-DTMP is a DHFR inhibitor with Ki of 5.1 nM (DHFR WT) and 34.3 nM (DHFR L28R), respectively. 4 '-DTMP carries a polar modification that induces additional local interactions with the enzyme. In particular, the hairpin structure on the M20 ring is related to the internal communication of the DHFR. 4 '-DTMP has potential inhibition of E.coli .
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Cat. No.: HY-131576
CAS No.: 491-97-4
Synonyms: dTDP
Thymidine 5′-diphosphate (dTDP) is a key product for pyrimidine synthesis in organisms. Thymidine 5′-diphosphate is generated via the phosphorylation of thymidine 5'-monophosphate (dTMP) catalyzed by thymidylate kinase (TMPK), a process requiring ATP and Mg 2+. Thymidine 5′-diphosphate is further catalyzed by TMPK into thymidine 5'-triphosphate (dTTP). Detection of Thymidine 5′-diphosphate levels enables the assessment of TMPK activity .
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Cat. No.: HY-W394006
CAS No.: 964-26-1
Synonyms: dUMP
Target:  

Endogenous Metabolite

Research Areas:  

Infection Metabolic Disease

2'-Deoxyuridine 5'-monophosphate (dUMP) is a deoxynucleotide that is reductively methylated to dTMP (2'-deoxythymidine 5'-monophosphate) by bisubstrate enzyme thymidylate synthase (TS). dTMP is a nucleotide required for DNA synthesis .
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Cat. No.: HY-W011142R
CAS No.: 42155-08-8
Synonyms: dUMP disodium (Standard)
2'-Deoxyuridine 5'-monophosphate (disodium) (Standard) is the analytical standard of 2'-Deoxyuridine 5'-monophosphate (disodium) (HY-W011142). This product is intended for research and analytical applications. 2'-Deoxyuridine 5'-monophosphate (dUMP) disodium is a deoxynucleotide that is reductively methylated to dTMP (2'-deoxythymidine 5'-monophosphate) by bisubstrate enzyme thymidylate synthase (TS). dTMP is a nucleotide required for DNA synthesis .
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Cat. No.: HY-P70012
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: DTYMK; Thymidylate Kinase; Deoxythymidylate Kinase; Deoxythymidylate Kinase (Thymidylate Kinase); dTMP Kinase; Thymidylate (dTMP) Kinase; CDC8; Tmp_locus_5; TYMK; PP3731; TMPK; CONPM
Species:  
Source:  
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Cat. No.: HY-E70912
Target:  

Thymidylate Synthase

Research Areas:  

Metabolic Disease

Prokaryotic thymidylate kinase (EC 2.7.4.9) is an enzyme that transfers phosphorus-containing groups (phosphotransferases) using phosphate groups as acceptors. Prokaryotic thymidylate kinase participates in pyrimidine metabolism. Its two substrates are ATP and dTMP, and its two products are ADP and dTDP.
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Cat. No.: HY-P72177
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Thymidylate kinase; EC:2.7.4.9; dTMP kinase; tmk; BAMEG_0039
Species:  
Source:  
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Cat. No.: HY-131576B
CAS No.: 28120-41-4
Synonyms: dTDP disodium
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

Thymidine 5′-diphosphate (dTDP) disodium is a key product for pyrimidine synthesis in organisms. Thymidine 5′-diphosphate is generated via the phosphorylation of thymidine 5'-monophosphate (dTMP) catalyzed by thymidylate kinase (TMPK), a process requiring ATP and Mg 2+. Thymidine 5′-diphosphate disodium is further catalyzed by TMPK into thymidine 5'-triphosphate (dTTP). Detection of Thymidine 5′-diphosphate levels enables the assessment of TMPK activity .
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